FATTY ACID SYNTHESIS IN NORMAL AND COLD-ACCLIMATED RATS.

Rats acclimated to either 0–2 °C or 25 °C were given glucose-C14 via stomach tube and then sacrificed at , 1, 6, or 24 hours. The cold-acclimated rats incorporated no more and possibly less C14 into fatty acids than did the rats acclimated to 25 °C. Evidence is presented which indicates that the white adipose tissue probably did not play a quantitatively important role in the conversion of the glucose-C14 to fatty acid. Also, the data indicate that lipogenesis was not a major pathway of the glucose-C14 metabolism.