Development of a Human APOE Knock-in Mouse Model for Study of Cognitive Function After Cancer Chemotherapy
暂无分享,去创建一个
J. Mandelblatt | C. Albanese | Olga C. Rodriguez | Yichien Lee | Tamar Demby | G. William Rebeck | Andrew P. Speidell
[1] J. VanMeter,et al. Cancer-Related Cognitive Outcomes Among Older Breast Cancer Survivors in the Thinking and Living With Cancer Study. , 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[2] G. Winocur,et al. Chemotherapy and cognition: International cognition and cancer task force recommendations for harmonising preclinical research. , 2018, Cancer treatment reviews.
[3] D. Butterfield,et al. Doxorubicin-induced elevated oxidative stress and neurochemical alterations in brain and cognitive decline: protection by MESNA and insights into mechanisms of chemotherapy-induced cognitive impairment (“chemobrain”) , 2018, Oncotarget.
[4] C. Albanese,et al. Divergent brain changes in two audiogenic rat strains: A voxel-based morphometry and diffusion tensor imaging comparison of the genetically epilepsy prone rat (GEPR-3) and the Wistar Audiogenic Rat (WAR) , 2018, Neurobiology of Disease.
[5] Andrew Saykin,et al. Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation , 2017, Alzheimer's & Dementia.
[6] Xiaochuan Sun,et al. Bexarotene protects against traumatic brain injury in mice partially through apolipoprotein E , 2017, Neuroscience.
[7] G. Rebeck,et al. Alzheimer's Disease Genetic Risk Factor APOE-ε4 Also Affects Normal Brain Function. , 2016, Current Alzheimer research.
[8] A. Jemal,et al. Cancer treatment and survivorship statistics, 2016 , 2016, CA: a cancer journal for clinicians.
[9] Julia H. Rowland,et al. Anticipating the “Silver Tsunami”: Prevalence Trajectories and Comorbidity Burden among Older Cancer Survivors in the United States , 2016, Cancer Epidemiology, Biomarkers & Prevention.
[10] S. Dumanis,et al. Identification and modification of amyloid-independent phenotypes of APOE4 mice , 2016, Experimental Neurology.
[11] A. Smit,et al. Neurobiological changes by cytotoxic agents in mice , 2016, Behavioural Brain Research.
[12] S. Kesler,et al. Neurotoxic Effects of Anthracycline- vs Nonanthracycline-Based Chemotherapy on Cognition in Breast Cancer Survivors. , 2016, JAMA oncology.
[13] A. Saykin,et al. Imaging Brain Networks After Cancer and Chemotherapy: Advances Toward Etiology and Unanswered Questions. , 2016, JAMA oncology.
[14] Manasi Malik,et al. Genetics ignite focus on microglial inflammation in Alzheimer’s disease , 2015, Molecular Neurodegeneration.
[15] T. Ahles,et al. Doxorubicin and cyclophosphamide induce cognitive dysfunction and activate the ERK and AKT signaling pathways , 2015, Behavioural Brain Research.
[16] Burkhard Becher,et al. Immune attack: the role of inflammation in Alzheimer disease , 2015, Nature Reviews Neuroscience.
[17] Pinal N. Kanabar,et al. APOE‐modulated Aβ‐induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective , 2015, Journal of neurochemistry.
[18] C. Limoli,et al. Stem cell transplantation reverses chemotherapy-induced cognitive dysfunction. , 2015, Cancer research.
[19] Jason H. Moore,et al. Longitudinal assessment of cognitive changes associated with adjuvant treatment for breast cancer: the impact of APOE and smoking , 2014, Psycho-oncology.
[20] A. Smit,et al. Sheltering Behavior and Locomotor Activity in 11 Genetically Diverse Common Inbred Mouse Strains Using Home-Cage Monitoring , 2014, PloS one.
[21] J. Rowland,et al. Cancer survivorship issues: life after treatment and implications for an aging population. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[22] Jeanne S Mandelblatt,et al. Cognitive effects of cancer systemic therapy: implications for the care of older patients and survivors. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[23] G. Rebeck,et al. Aging reduces glial uptake and promotes extracellular accumulation of Aβ from a lentiviral vector , 2014, Front. Aging Neurosci..
[24] M. LaDu,et al. Human APOE4 increases microglia reactivity at Aβ plaques in a mouse model of Aβ deposition , 2014, Journal of Neuroinflammation.
[25] A. Saykin,et al. Cognitive impairment in older patients with breast cancer before systemic therapy: is there an interaction between cancer and comorbidity? , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[26] L. Carey,et al. Effect of cytotoxic chemotherapy on markers of molecular age in patients with breast cancer. , 2014, Journal of the National Cancer Institute.
[27] F. Joly,et al. Chemotherapy-induced long-term alteration of executive functions and hippocampal cell proliferation: Role of glucose as adjuvant , 2014, Neuropharmacology.
[28] C. Rosenfeld,et al. Barnes maze testing strategies with small and large rodent models. , 2014, Journal of visualized experiments : JoVE.
[29] J. VanMeter,et al. Cognitive effects of cancer and its treatments at the intersection of aging: what do we know; what do we need to know? , 2013, Seminars in oncology.
[30] A. Saykin,et al. Neuroimaging biomarkers and cognitive function in non-CNS cancer and its treatment: Current status and recommendations for future research , 2013, Brain Imaging and Behavior.
[31] Hagen B. Huttner,et al. Dynamics of Hippocampal Neurogenesis in Adult Humans , 2013, Cell.
[32] E. Weeber,et al. Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex. , 2013, Learning & memory.
[33] Huaxi Xu,et al. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy , 2013, Nature Reviews Neurology.
[34] R. Hancock,et al. The Liver X Receptor Agonist GW3965 Improves Recovery from Mild Repetitive Traumatic Brain Injury in Mice Partly through Apolipoprotein E , 2013, PloS one.
[35] S. Dumanis,et al. APOE genotype affects the pre‐synaptic compartment of glutamatergic nerve terminals , 2013, Journal of neurochemistry.
[36] S. Dumanis,et al. APOE genotype alters glial activation and loss of synaptic markers in mice , 2012, Glia.
[37] C. Limoli,et al. Impaired Cognitive Function and Hippocampal Neurogenesis following Cancer Chemotherapy , 2012, Clinical Cancer Research.
[38] H. Arrighi,et al. Prevalence of Apolipoprotein E4 Genotype and Homozygotes (APOE e4/4) among Patients Diagnosed with Alzheimer’s Disease: A Systematic Review and Meta-Analysis , 2011, Neuroepidemiology.
[39] M. Dodd,et al. A prospective longitudinal study of chemotherapy-induced cognitive changes in breast cancer patients , 2011, Supportive Care in Cancer.
[40] Jitbanjong Tangpong,et al. Doxorubicin-induced central nervous system toxicity and protection by xanthone derivative of Garcinia Mangostana , 2011, Neuroscience.
[41] C. Colton,et al. Apolipoprotein E and Peptide Mimetics Modulate Inflammation by Binding the SET Protein and Activating Protein Phosphatase 2A , 2011, The Journal of Immunology.
[42] J. Fardell,et al. Neurobiological basis of chemotherapy-induced cognitive impairment: A review of rodent research , 2011, Neuroscience & Biobehavioral Reviews.
[43] Eric J Feuer,et al. Projections of the cost of cancer care in the United States: 2010-2020. , 2011, Journal of the National Cancer Institute.
[44] Andrew J Saykin,et al. Longitudinal assessment of cognitive changes associated with adjuvant treatment for breast cancer: impact of age and cognitive reserve. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[45] Sung-Ho Kim,et al. Cyclophosphamide impairs hippocampus-dependent learning and memory in adult mice: Possible involvement of hippocampal neurogenesis in chemotherapy-induced memory deficits , 2010, Neurobiology of Learning and Memory.
[46] P. Matthews,et al. Distinct patterns of brain activity in young carriers of the APOE e4 allele , 2009, NeuroImage.
[47] C. Kelche,et al. Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks , 2008, Behavioural Brain Research.
[48] C. Jack,et al. MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers , 2008, Brain : a journal of neurology.
[49] R. Raffa,et al. Effects of chemotherapeutic agents 5-fluorouracil and methotrexate alone and combined in a mouse model of learning and memory , 2008, Psychopharmacology.
[50] M. Simionescu,et al. Inflammatory Signaling Pathways Regulating ApoE Gene Expression in Macrophages* , 2007, Journal of Biological Chemistry.
[51] D. Butterfield,et al. Adriamycin‐mediated nitration of manganese superoxide dismutase in the central nervous system: insight into the mechanism of chemobrain , 2007, Journal of neurochemistry.
[52] R. Roesler,et al. Cancer Chemotherapy and Cognitive Function in Rodent Models: Memory Impairment Induced by Cyclophosphamide in Mice , 2006, Clinical Cancer Research.
[53] D. Schmechel,et al. Marked regional differences of brain human apolipoprotein e expression in targeted replacement mice , 2004, Neuroscience.
[54] S. Dunnett,et al. Behavioural profiles of inbred mouse strains used as transgenic backgrounds. II: cognitive tests , 2004, Genes, brain, and behavior.
[55] L. Baxter,et al. Longitudinal changes in cognition and behavior in asymptomatic carriers of the APOE e4 allele , 2004, Neurology.
[56] R. Theriault,et al. The cognitive sequelae of standard‐dose adjuvant chemotherapy in women with breast carcinoma , 2004, Cancer.
[57] J. Wesson Ashford,et al. ApoE genotype accounts for the vast majority of AD risk and AD pathology , 2004, Neurobiology of Aging.
[58] A. Granholm,et al. Ovarian hormones and cognition in the aged female rat: I. Long-term, but not short-term, ovariectomy enhances spatial performance. , 2003, Behavioral neuroscience.
[59] A. Saykin,et al. The relationship of APOE genotype to neuropsychological performance in long‐term cancer survivors treated with standard dose chemotherapy , 2003, Psycho-oncology.
[60] N. Nathoo,et al. Apolipoprotein E polymorphism and outcome after closed traumatic brain injury: influence of ethnic and regional differences. , 2003, Journal of neurosurgery.
[61] M. Dewey,et al. Dementia, cognitive impairment and mortality in persons aged 65 and over living in the community: a systematic review of the literature , 2001, International journal of geriatric psychiatry.
[62] Karl J. Friston,et al. Voxel-Based Morphometry—The Methods , 2000, NeuroImage.
[63] Daniel Bandy,et al. Hippocampal volumes in cognitively normal persons at genetic risk for Alzheimer's disease , 1998, Annals of neurology.
[64] G. Rebeck,et al. APOE Genotype Alters Immunoglobulin Subtypes in Knock-In Mice. , 2015, Journal of Alzheimer's disease : JAD.
[65] A. Smit,et al. Cognitive impact of cytotoxic agents in mice , 2014, Psychopharmacology.
[66] P. Wigmore. The effect of systemic chemotherapy on neurogenesis, plasticity and memory. , 2013, Current topics in behavioral neurosciences.
[67] C. Rampon,et al. Adult Hippocampal Neurogenesis, Synaptic Plasticity and Memory: Facts and Hypotheses , 2007, Reviews in the neurosciences.
[68] R. Martins,et al. APOE-ε4 and APOE −491A polymorphisms in individuals with subjective memory loss , 2002, Molecular Psychiatry.
[69] R. Packer,et al. An animal model to detect the neuropsychological toxicity of anticancer agents. , 1989, Medical and pediatric oncology.
[70] L. Rorke,et al. An animal model to detect learning deficits following treatment of the immature brain. Studies using radiation and methotrexate. , 1983, Child's brain.