Functional analysis of cytosolic tryparedoxin peroxidase in antimony-resistant and –susceptible Leishmania braziliensis and Leishmania infantum lines

[1]  Bill Bynum,et al.  Lancet , 2015, The Lancet.

[2]  F. Frézard,et al.  Molecular characterization of the MRPA transporter and antimony uptake in four New World Leishmania spp. susceptible and resistant to antimony☆ , 2013, International journal for parasitology. Drugs and drug resistance.

[3]  C. Pirovani,et al.  Comparative proteomic analysis of antimony-resistant and -susceptible Leishmania braziliensis and Leishmania infantum chagasi lines. , 2013, Molecular and biochemical parasitology.

[4]  S. Wyllie,et al.  Comparative proteomics profiling of a gentamicin-attenuated Leishmania infantum cell line identifies key changes in parasite thiol-redox metabolism. , 2012, Journal of proteomics.

[5]  A. Fairlamb,et al.  Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates. , 2010, Molecular and biochemical parasitology.

[6]  S. Sundar,et al.  Drug Resistance in Leishmaniasis , 2010, Journal of global infectious diseases.

[7]  S. Murta/,et al.  Selection and phenotype characterization of potassium antimony tartrate-resistant populations of four New World Leishmania species , 2010, Parasitology Research.

[8]  J. Ruiz,et al.  Molecular characterization of cytosolic and mitochondrial tryparedoxin peroxidase in Trypanosoma cruzi populations susceptible and resistant to benznidazole , 2009, Parasitology Research.

[9]  A. Tomás,et al.  Peroxidases of trypanosomatids. , 2008, Antioxidants & redox signaling.

[10]  C. Shaha,et al.  Crucial role of cytosolic tryparedoxin peroxidase in Leishmania donovani survival, drug response and virulence , 2008, Molecular microbiology.

[11]  A. Fairlamb,et al.  Roles of Trypanothione S-Transferase and Tryparedoxin Peroxidase in Resistance to Antimonials , 2008, Antimicrobial Agents and Chemotherapy.

[12]  A. Fairlamb,et al.  Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony , 2007, Parasitology.

[13]  G. Schönian,et al.  Multilocus microsatellite typing (MLMT) reveals genetically isolated populations between and within the main endemic regions of visceral leishmaniasis. , 2007, Microbes and infection.

[14]  S. Goldenberg,et al.  Increased expression of iron-containing superoxide dismutase-A (TcFeSOD-A) enzyme in Trypanosoma cruzi population with in vitro-induced resistance to benznidazole. , 2006, Acta tropica.

[15]  S. Goldenberg,et al.  Deletion of copies of the gene encoding old yellow enzyme (TcOYE), a NAD(P)H flavin oxidoreductase, associates with in vitro-induced benznidazole resistance in Trypanosoma cruzi. , 2006, Molecular and biochemical parasitology.

[16]  M. Lipoldová,et al.  Genetic susceptibility to infectious disease: lessons from mouse models of leishmaniasis , 2006, Nature Reviews Genetics.

[17]  A. Fairlamb,et al.  Dual Action of Antimonial Drugs on Thiol Redox Metabolism in the Human Pathogen Leishmania donovani* , 2004, Journal of Biological Chemistry.

[18]  J. Turrens Oxidative stress and antioxidant defenses: a target for the treatment of diseases caused by parasitic protozoa. , 2004, Molecular aspects of medicine.

[19]  S. Beverley,et al.  Improvements in transfection efficiency and tests of RNA interference (RNAi) approaches in the protozoan parasite Leishmania. , 2003, Molecular and biochemical parasitology.

[20]  M. Ouellette,et al.  Proteome Mapping of the Protozoan Parasite Leishmania and Application to the Study of Drug Targets and Resistance Mechanisms* , 2003, Molecular & Cellular Proteomics.

[21]  L. Flohé,et al.  Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum. , 2002, Free radical biology & medicine.

[22]  L. Flohé,et al.  Tryparedoxin peroxidase of Leishmania donovani: molecular cloning, heterologous expression, specificity, and catalytic mechanism. , 2002, Archives of biochemistry and biophysics.

[23]  S. Sundar Drug resistance in Indian visceral leishmaniasis , 2001, Tropical medicine & international health : TM & IH.

[24]  S. Beverley,et al.  Blasticidin resistance: a new independent marker for stable transfection of Leishmania. , 2000, Molecular and biochemical parasitology.

[25]  S. Wilkinson,et al.  Distinct Mitochondrial and Cytosolic Enzymes Mediate Trypanothione-dependent Peroxide Metabolism in Trypanosoma cruzi * , 2000, The Journal of Biological Chemistry.

[26]  E. Tannich,et al.  Metronidazole Resistance in the Protozoan Parasite Entamoeba histolytica Is Associated with Increased Expression of Iron-containing Superoxide Dismutase and Peroxiredoxin and Decreased Expression of Ferredoxin 1 and Flavin Reductase* , 1999, The Journal of Biological Chemistry.

[27]  M. Levick,et al.  Identification and characterisation of a functional peroxidoxin from Leishmania major. , 1998, Molecular and biochemical parasitology.

[28]  L. Vanhamme,et al.  Control of gene expression in trypanosomes. , 1995, Microbiological reviews.

[29]  K. B. Marzochi,et al.  Tegumentary and visceral leishmaniases in Brazil: emerging anthropozoonosis and possibilities for their control. , 1994, Cadernos de saude publica.

[30]  M. Ouellette,et al.  P-glycoprotein overexpression in methotrexate-resistant Leishmania tropica. , 1994, Biochemical pharmacology.

[31]  J. Koella,et al.  A comparison of three methods of estimating EC50 in studies of drug resistance of malaria parasites. , 1993, Acta tropica.

[32]  J. Berman,et al.  Sodium stibogluconate (Pentostam) inhibition of glucose catabolism via the glycolytic pathway, and fatty acid beta-oxidation in Leishmania mexicana amastigotes. , 1987, Biochemical pharmacology.

[33]  J. Bartholomew,et al.  The binding of crystal violet by isolated bacterial cell-wall material. , 1969, Journal of general microbiology.

[34]  W. Colli,et al.  Trypanosoma cruzi response to the oxidative stress generated by hydrogen peroxide. , 2004, Molecular and biochemical parasitology.

[35]  A. Fairlamb,et al.  Metabolism and functions of trypanothione in the Kinetoplastida. , 1992, Annual review of microbiology.

[36]  R. Schirmer,et al.  Oxidative stress as a defense mechanism against parasitic infections. , 1987, Free radical research communications.