The Eccentric Spheres Model as the Basis for a Study of the Role of Geometry and Inhomogeneities in Electrocardiography

To study the role of internal geometry and inhomogeneities in the "forward problem" of electrocardiography (ECG), a mathematical model was constructed which permitted manipulation of these variables. The model, which consists of two eccentric systems of concentric spheres, contains all the important torso compartments, namely the blood cavity, the myocardium, the pericardium, the lung region, the surface muscle layer, and the subcutaneous fat. An analytic solution is found in the form of a double series expansion in Legendre polynomials. The integrated effect of the inhomogeneities on the surface potential distribution is investigated. The model demonstrates the importance of interactions between the various torso components in determining the potential distribution at the surface.

[1]  S. Rush,et al.  Inhomogeneities as a cause of multiple peaks of heart potential on the body surface: theoretical studies. , 1971, IEEE transactions on bio-medical engineering.

[2]  D. Durrer,et al.  Total Excitation of the Isolated Human Heart , 1970, Circulation.

[3]  R. M. Arthur,et al.  Effect of inhomogeneities on the apparent location and magnitude of a cardiac current dipole source. , 1970, IEEE transactions on bio-medical engineering.

[4]  E. W. Reynolds,et al.  An Experimental Study of Propagated Electrical Activity in the Canine Heart , 1970, Circulation research.

[5]  R. Bayley,et al.  Changes in the body's QRS surface potentials produced by alterations in certain compartments of the nonhomogeneous conducting model. , 1969, American heart journal.

[6]  S. Rush,et al.  Qualitative effects of thoracic resistivity variations on the interpretation of electrocardiograms: the low resistance surface layer. , 1968, American Heart Journal.

[7]  D. B. Heppner,et al.  Considerations of quasi-stationarity in electrophysiological systems. , 1967, The Bulletin of mathematical biophysics.

[8]  D A BRODY,et al.  An Official Journal of the American Heart Association Body Surface Potential Distribution : COMPARISON OF NATURALLY AND ARTIFICIALLY PRODUCED SIGNALS AS ANALYZED BY DIGITAL COMPUTER , 2005 .

[9]  S. Rush,et al.  Resistivity of Body Tissues at Low Frequencies , 1963, Circulation research.

[10]  R. Okada An experimental study of multiple dipole potentials and the effects of inhomogeneities in volume conductors. , 1957, American heart journal.

[11]  A. C. Young,et al.  VENTRICULAR DEPOLARIZATION AND THE GENESIS OF QRS , 1957, Annals of the New York Academy of Sciences.

[12]  D. Brody A Theoretical Analysis of Intracavitary Blood Mass Influence on the Heart‐Lead Relationship , 1956, Circulation research.