ANEMIA OF THE NEW-BORN WITHOUT ERYTHROBLASTOSIS: OBSERVATIONS AT AUTOPSY

The subject of anemia of the new-born has recently taken on a new interest. Finkelstein 1 (in 1911) and Lichtenstein 2 (1917) first drew attention to the possible occurrence of anemia in the new-born. Ecklin 3 (1919), however, was the first to report "a case of severe anemia in the new-born." Following this, cases have appeared under the titles of idiopathic, primary, essential and congenital anemia. Pritchard and Smith 4 (1931), in a careful survey of the literature, tabulated fifteen cases and mentioned fourteen additional cases observed though not described by Grulee, Foote, McClelland and Blackfan et al. Abt 5 (1932) analyzed the reported cases and presented a case of his own which also showed a mononuclear erythrophagocytosis in the circulating blood. Diamond, Blackfan and Baty 6 (1932) added six cases and concluded that universal edema of the fetus, icterus gravis neonatorum and anemia of the new-born are closely related