Activating adenosine A1 receptor accelerates PC12 cell injury via ADORA1/PKC/KATP pathway after intermittent hypoxia exposure

[1]  Hyunju Kim,et al.  Protein Kinase C Isoforms Differentially Regulate Hypoxia‐Inducible Factor‐1α Accumulation in Cancer Cells , 2016, Journal of cellular biochemistry.

[2]  Y. Koo,et al.  Can Continuous Positive Airway Pressure Reduce the Risk of Stroke in Obstructive Sleep Apnea Patients? A Systematic Review and Meta-Analysis , 2016, PloS one.

[3]  G. Caimi,et al.  Obstructive Sleep Apnea Syndrome: Links Betwen Pathophysiology and Cardiovascular Complications. , 2015, Clinical and investigative medicine. Medecine clinique et experimentale.

[4]  V. Babich,et al.  Dual Effect of Adenosine A1 Receptor Activation on Renal O2 Consumption , 2015, Journal of cellular physiology.

[5]  O. Resta,et al.  Obstructive Sleep Apnea, Hypertension, and Their Additive Effects on Atherosclerosis , 2015, Biochemistry research international.

[6]  N. Ayas,et al.  The effect of OSA on work disability and work-related injuries. , 2015, Chest.

[7]  E. Scoditti,et al.  Obstructive sleep apnoea syndrome: a new paradigm by chronic nocturnal intermittent hypoxia and sleep disruption , 2015, Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale.

[8]  L. Jianyong,et al.  [Continuous positive airway pressure treatment for functional cardiac arrhythmias combined with obstructive sleep apnea hypopnea syndrome]. , 2015, Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery.

[9]  L. Pei,et al.  Neuronal KATP channels mediate hypoxic preconditioning and reduce subsequent neonatal hypoxic–ischemic brain injury , 2015, Experimental Neurology.

[10]  L. Folkow,et al.  KATP-channels play a minor role in the protective hypoxic shut-down of cerebellar activity in eider ducks (Somateria mollissima) , 2015, Neuroscience.

[11]  H. Landolt,et al.  Adenosine, caffeine, and performance: from cognitive neuroscience of sleep to sleep pharmacogenetics. , 2015, Current topics in behavioral neurosciences.

[12]  Y. Liu,et al.  The Protective Effect of Epoxyeicosatrienoic Acids on Cerebral Ischemia/Reperfusion Injury is Associated with PI3K/Akt Pathway and ATP-Sensitive Potassium Channels , 2015, Neurochemical Research.

[13]  M. Trincavelli,et al.  Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy , 2014, Cell Death and Disease.

[14]  S. Giunta,et al.  Dual blockade of the A1 and A2A adenosine receptor prevents amyloid beta toxicity in neuroblastoma cells exposed to aluminum chloride. , 2014, The international journal of biochemistry & cell biology.

[15]  M. Hussain,et al.  Protein kinase C (PKC) mediated interaction between conexin43 (Cx43) and K(+)(ATP) channel subunit (Kir6.1) in cardiomyocyte mitochondria: Implications in cytoprotection against hypoxia induced cell apoptosis. , 2014, Cellular signalling.

[16]  Xiao-hong Cai,et al.  Endoplasmic reticulum stress plays critical role in brain damage after chronic intermittent hypoxia in growing rats , 2014, Experimental Neurology.

[17]  Yuan-yuan Wang,et al.  [Expression of KATP in pulmonary artery smooth muscle cells under hypoxia-hypercapnia condition and the relationship with p38 MAPK pathway]. , 2014, Sheng li xue bao : [Acta physiologica Sinica].

[18]  Lubo Zhang,et al.  Gestational Hypoxia Up-regulates Protein Kinase C and Inhibits Calcium-Activated Potassium Channels in Ovine Uterine Arteries , 2014, International journal of medical sciences.

[19]  Bhupesh Sharma,et al.  Protective effects of phosphodiesterase-1 (PDE1) and ATP sensitive potassium (KATP) channel modulators against 3-nitropropionic acid induced behavioral and biochemical toxicities in experimental Huntington׳s disease. , 2014, European journal of pharmacology.

[20]  W. Cao,et al.  Omega-3 PUFAs induce apoptosis of gastric cancer cells via ADORA1. , 2014, Frontiers in bioscience.

[21]  T. Eckle,et al.  Attenuating myocardial ischemia by targeting A2B adenosine receptors. , 2013, Trends in molecular medicine.

[22]  I. Lucki,et al.  VMAT1 deletion causes neuronal loss in the hippocampus and neurocognitive deficits in spatial discrimination , 2013, Neuroscience.

[23]  M. Blackburn,et al.  Adenosine signaling during acute and chronic disease states , 2013, Journal of Molecular Medicine.

[24]  M. Xi,et al.  Apnea produces excitotoxic hippocampal synapses and neuronal apoptosis , 2012, Experimental Neurology.

[25]  D. Navajas,et al.  A bioreactor for subjecting cultured cells to fast-rate intermittent hypoxia , 2012, Respiratory Physiology & Neurobiology.

[26]  S. Steinberg.  Cardiac actions of protein kinase C isoforms. , 2012, Physiology.

[27]  N. Zhang,et al.  Determination of PKC isoform-specific protein expression in pulmonary arteries of rats with chronic hypoxia-induced pulmonary hypertension , 2012, Medical science monitor : international medical journal of experimental and clinical research.

[28]  Alison M. Thomas,et al.  Regulation of the ATP-sensitive Potassium Channel Subunit, Kir6.2, by a Ca2+-dependent Protein Kinase C* , 2011, The Journal of Biological Chemistry.

[29]  Qian Yang,et al.  Cardioprotective effect of polydatin against ischemia/reperfusion injury: roles of protein kinase C and mito K(ATP) activation. , 2011, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[30]  J. Sabourin,et al.  Adenosine A1 receptor activation is arrhythmogenic in the developing heart through NADPH oxidase/ERK- and PLC/PKC-dependent mechanisms. , 2011, Journal of molecular and cellular cardiology.

[31]  T. Eckle,et al.  Ischemia and reperfusion—from mechanism to translation , 2011, Nature Medicine.

[32]  D. Gozal,et al.  Leukotriene B4 receptor-1 mediates intermittent hypoxia-induced atherogenesis. , 2011, American journal of respiratory and critical care medicine.

[33]  D. Gozal,et al.  Intermittent Hypoxia-Induced Cognitive Deficits Are Mediated by NADPH Oxidase Activity in a Murine Model of Sleep Apnea , 2011, PloS one.

[34]  A. Doney,et al.  Intracellular ATP Influences Synaptic Plasticity in Area CA1 of Rat Hippocampus via Metabolism to Adenosine and Activity-Dependent Activation of Adenosine A1 Receptors , 2011, The Journal of Neuroscience.

[35]  Qinglei Zhu,et al.  The protective roles of mitochondrial ATP-sensitive potassium channels during hypoxia–ischemia–reperfusion in brain , 2011, Neuroscience Letters.

[36]  S. Ito,et al.  Adenosine and inosine release during hypoxia in the isolated spinal cord of neonatal rats , 2010, British journal of pharmacology.

[37]  B. Fredholm,et al.  Adenosine receptors as drug targets. , 2010, Experimental cell research.

[38]  D. Weihrauch,et al.  KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy , 2010, Molecular pain.

[39]  A. Nadeem,et al.  A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells. , 2009, American journal of physiology. Heart and circulatory physiology.

[40]  F. Carreño,et al.  Chronic sustained and intermittent hypoxia reduce function of ATP-sensitive potassium channels in nucleus of the solitary tract. , 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

[41]  B B Fredholm,et al.  Adenosine, an endogenous distress signal, modulates tissue damage and repair , 2007, Cell Death and Differentiation.

[42]  M. Jarvis,et al.  Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors. , 2005, Current topics in medicinal chemistry.

[43]  A. Wilde.  Role of ATP-sensitive K+ channel current in ischemic arrhythmias , 1993, Cardiovascular Drugs and Therapy.

[44]  D. Alkon,et al.  Pharmacological protection of synaptic function, spatial learning, and memory from transient hypoxia in rats. , 2002, The Journal of pharmacology and experimental therapeutics.

[45]  B. Fredholm,et al.  International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. , 2001, Pharmacological reviews.

[46]  S. Seino,et al.  Protective Role of ATP-Sensitive Potassium Channels in Hypoxia-Induced Generalized Seizure , 2001, Science.

[47]  D. Gozal,et al.  Behavioral and Anatomical Correlates of Chronic Episodic Hypoxia during Sleep in the Rat , 2001, The Journal of Neuroscience.

[48]  F. Ashcroft,et al.  New windows on the mechanism of action of K(ATP) channel openers. , 2000, Trends in pharmacological sciences.

[49]  H. Zimmermann.  Extracellular metabolism of ATP and other nucleotides , 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.

[50]  A. Martelli,et al.  Multiple biological responses activated by nuclear protein kinase C , 1999, Journal of cellular biochemistry.

[51]  A. Toker.  Signaling through protein kinase C. , 1998, Frontiers in bioscience : a journal and virtual library.

[52]  Y. Kurachi,et al.  Function, Regulation, Pharmacology, and Molecular Structure of ATP‐Sensitive K+ Channels in the Cardiovascular System , 1997, Journal of cardiovascular electrophysiology.

[53]  Syed Jamal Mustafa,et al.  Adenosine A1 receptor-induced upregulation of protein kinase C: role of pertussis toxin-sensitive G protein(s). , 1995, The American journal of physiology.

[54]  Syed Jamal Mustafa,et al.  Adenosine analogues prevent phorbol ester-induced PKC depletion in porcine coronary artery via A1 receptor. , 1995, American Journal of Physiology.

[55]  M. Janse,et al.  Electrophysiological mechanisms of ventricular arrhythmias resulting from myocardial ischemia and infarction. , 1989, Physiological reviews.