Proceedings from the Albert Charitable Trust Inaugural Workshop on white matter and cognition in aging

[1]  D. Norris,et al.  Contribution of acute infarcts to cerebral small vessel disease progression , 2019, Annals of neurology.

[2]  Andrew Gibson,et al.  Impaired behavioural flexibility related to white matter microgliosis in the TgAPP21 rat model of Alzheimer disease , 2019, Brain, Behavior, and Immunity.

[3]  K. Jin,et al.  Systemic milieu and age-related deterioration , 2019, GeroScience.

[4]  Philippe Pouliot,et al.  Systolic hypertension-induced neurovascular unit disruption magnifies vascular cognitive impairment in middle-age atherosclerotic LDLr−/−:hApoB+/+ mice , 2019, GeroScience.

[5]  Farzaneh A. Sorond,et al.  Age-related decline in peripheral vascular health predicts cognitive impairment , 2019, GeroScience.

[6]  T. Kiss,et al.  Central IGF-1 protects against features of cognitive and sensorimotor decline with aging in male mice , 2019, GeroScience.

[7]  Philippe Pouliot,et al.  High Systolic Blood Pressure Induces Cerebral Microvascular Endothelial Dysfunction, Neurovascular Unit Damage, and Cognitive Decline in Mice , 2019, Hypertension.

[8]  Stephen E. Jones,et al.  Cortical neuronal densities and cerebral white matter demyelination in multiple sclerosis: a retrospective study , 2018, The Lancet Neurology.

[9]  V. Hachinski,et al.  APP21 transgenic rats develop age-dependent cognitive impairment and microglia accumulation within white matter tracts , 2018, Journal of Neuroinflammation.

[10]  Evan Z. Macosko,et al.  Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain , 2018, Cell.

[11]  M. Ewers,et al.  Free water determines diffusion alterations and clinical status in cerebral small vessel disease , 2018, Alzheimer's & Dementia.

[12]  D. Norris,et al.  Investigating the origin and evolution of cerebral small vessel disease: The RUN DMC – InTENse study , 2018, European stroke journal.

[13]  Karl Herrup,et al.  DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia , 2018, Alzheimer's & Dementia.

[14]  C. Gu,et al.  Regulation of Central Nervous System Myelination in Higher Brain Functions , 2018, Neural plasticity.

[15]  Eric E. Smith,et al.  Cerebral amyloid angiopathy as a cause of neurodegeneration , 2018, Journal of neurochemistry.

[16]  D. Rosene,et al.  Candidate molecular pathways of white matter vulnerability in the brain of normal aging rhesus monkeys , 2018, GeroScience.

[17]  Peter J. Park,et al.  Aging and neurodegeneration are associated with increased mutations in single human neurons , 2017, Science.

[18]  K. Herrup,et al.  Re‐imagining Alzheimer's disease – the diminishing importance of amyloid and a glimpse of what lies ahead , 2017, Journal of neurochemistry.

[19]  H. Markus,et al.  Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease , 2017, Neurology.

[20]  V. Hachinski,et al.  Behavioural inflexibility in a comorbid rat model of striatal ischemic injury and mutant hAPP overexpression , 2017, Behavioural Brain Research.

[21]  M. Monje,et al.  Wrapped to Adapt: Experience-Dependent Myelination , 2017, Neuron.

[22]  T. Kiss,et al.  Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer’s disease , 2017, GeroScience.

[23]  Ernesto Fedele,et al.  The Amyloid Cascade Hypothesis in Alzheimer’s Disease: It’s Time to Change Our Mind , 2017, Current neuropharmacology.

[24]  Nadine C. Heyworth,et al.  Microglia activation and phagocytosis: relationship with aging and cognitive impairment in the rhesus monkey , 2017, GeroScience.

[25]  E. Audinat,et al.  Microglia in CNS development: Shaping the brain for the future , 2017, Progress in Neurobiology.

[26]  T. Kiss,et al.  Cerebromicrovascular dysfunction predicts cognitive decline and gait abnormalities in a mouse model of whole brain irradiation-induced accelerated brain senescence , 2017, GeroScience.

[27]  H. Vrenken,et al.  White Matter Hyperintensity Volume and Cerebral Perfusion in Older Individuals with Hypertension Using Arterial Spin-Labeling , 2016, American Journal of Neuroradiology.

[28]  S. Greenberg,et al.  Progression of Brain Network Alterations in Cerebral Amyloid Angiopathy , 2016, Stroke.

[29]  B. Boeve,et al.  Multiple sclerosis masquerading as Alzheimer-type dementia: Clinical, radiological and pathological findings , 2016, Multiple sclerosis.

[30]  S. Greenberg,et al.  White matter hyperintensity patterns in cerebral amyloid angiopathy and hypertensive arteriopathy , 2016, Neurology.

[31]  E. Chang,et al.  Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse , 2016, Neuron.

[32]  H. Markus,et al.  Progression of MRI markers in cerebral small vessel disease: Sample size considerations for clinical trials , 2016, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[33]  Alan J. Thomas,et al.  Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia , 2015, Brain : a journal of neurology.

[34]  A. Araki,et al.  Diabetes mellitus and white matter hyperintensity , 2015, Geriatrics & gerontology international.

[35]  K. Kitamura,et al.  Adrenomedullin Therapy in Patients with Refractory Ulcerative Colitis: A Case Series , 2015, Digestive Diseases and Sciences.

[36]  K. Arai,et al.  Adrenomedullin promotes differentiation of oligodendrocyte precursor cells into myelin-basic-protein expressing oligodendrocytes under pathological conditions in vitro. , 2015, Stem cell research.

[37]  H. Iida,et al.  A Novel Mouse Model of Subcortical Infarcts with Dementia , 2015, The Journal of Neuroscience.

[38]  Lisa Cloonan,et al.  Determinants of white matter hyperintensity burden differ at the extremes of ages of ischemic stroke onset. , 2015, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

[39]  Jeffrey F. Thompson,et al.  Hypoxia-Induced Neuroinflammatory White-Matter Injury Reduced by Minocycline in SHR/SP , 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[40]  O. Ciccarelli,et al.  Exploring the origins of grey matter damage in multiple sclerosis , 2015, Nature Reviews Neuroscience.

[41]  Joanna M. Wardlaw,et al.  Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden , 2014, Neurology.

[42]  G. Dehaene-Lambertz,et al.  The early development of brain white matter: A review of imaging studies in fetuses, newborns and infants , 2014, Neuroscience.

[43]  T. Maniatis,et al.  An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex , 2014, The Journal of Neuroscience.

[44]  B. Zlokovic,et al.  The Pericyte: A Forgotten Cell Type with Important Implications for Alzheimer's Disease? , 2014, Brain pathology.

[45]  P. Durie,et al.  Lessons from the Mouse Model , 2013 .

[46]  Richard Frayne,et al.  Neurovascular decoupling is associated with severity of cerebral amyloid angiopathy , 2013, Neurology.

[47]  Douglas L. Rosene,et al.  Age-related changes in human and non-human primate white matter: from myelination disturbances to cognitive decline , 2011, AGE.

[48]  M. Ihara,et al.  Lessons from a Mouse Model Characterizing Features of Vascular Cognitive Impairment with White Matter Changes , 2011, Journal of aging research.

[49]  K. Nakao,et al.  Angiogenic and Vasoprotective Effects of Adrenomedullin on Prevention of Cognitive Decline After Chronic Cerebral Hypoperfusion in Mice , 2011, Stroke.

[50]  Terry L. Jernigan,et al.  The Basics of Brain Development , 2010, Neuropsychology Review.

[51]  Eric E. Smith,et al.  MRI Markers of Small Vessel Disease in Lobar and Deep Hemispheric Intracerebral Hemorrhage , 2010, Stroke.

[52]  H. Markus,et al.  The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis , 2010, BMJ : British Medical Journal.

[53]  Karl Zilles,et al.  Frontal White Matter Volume Is Associated with Brain Enlargement and Higher Structural Connectivity in Anthropoid Primates , 2010, PloS one.

[54]  D. Mozaffarian,et al.  Defining and Setting National Goals for Cardiovascular Health Promotion and Disease Reduction: The American Heart Association's Strategic Impact Goal Through 2020 and Beyond , 2010, Circulation.

[55]  Sandra Black,et al.  Understanding White Matter Disease: Imaging-Pathological Correlations in Vascular Cognitive Impairment , 2009, Stroke.

[56]  A. Levey,et al.  Development of transgenic rats producing human β-amyloid precursor protein as a model for Alzheimer's disease: Transgene and endogenous APP genes are regulated tissue-specifically , 2008, BMC Neuroscience.

[57]  D. Harvey,et al.  Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD , 2006, Neurology.

[58]  K. Nakao,et al.  The neuroprotective and vasculo-neuro-regenerative roles of adrenomedullin in ischemic brain and its therapeutic potential. , 2006, Endocrinology.

[59]  Yue Cao,et al.  Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[60]  K. Herrup,et al.  Loss of Neuronal Cell Cycle Control in Ataxia-Telangiectasia: A Unified Disease Mechanism , 2005, The Journal of Neuroscience.

[61]  P. Schoenemann,et al.  Prefrontal white matter volume is disproportionately larger in humans than in other primates , 2005, Nature Neuroscience.

[62]  C. Masters,et al.  Consensus neuropathological diagnosis of common dementia syndromes: testing and standardising the use of multiple diagnostic criteria , 2002, Acta Neuropathologica.

[63]  H. Damasio,et al.  Humans and great apes share a large frontal cortex , 2002, Nature Neuroscience.

[64]  G. Bartzokis,et al.  Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging study. , 2001, Archives of general psychiatry.

[65]  A Hofman,et al.  Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study , 2001, Journal of neurology, neurosurgery, and psychiatry.

[66]  J M Wardlaw,et al.  Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study: the Rotterdam Scan Study , 2001, Journal of neurology, neurosurgery, and psychiatry.

[67]  G C Roman,et al.  Brain infarction and the clinical expression of Alzheimer disease. , 1997, JAMA.

[68]  W. Markesbery,et al.  Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. , 1997, JAMA.

[69]  H. Braak,et al.  Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis , 1996, Acta Neuropathologica.