Genes, chromosomes & cancer

Specific areas covered include: -Chromosomal abnormalities in all benign and malignant disorders, including changes that occur during neoplastic progression -Changes in gene structure and regulation as a consequence of genomic rearrangements -Chromosomal alterations involving genes related to the regulation of cell proliferation and differentiation -The correlation between genomic abnormalities and cellular phenotypic alterations -The predictive value of alterations at the chromosomal and DNA levels in disease prognosis, and in designing and monitoring cancer therapies -Cytogenetic, molecular, and epidemiologic analyses of inherited disorders predisposing to cancer -Chromosomal and/or genetic damage caused by external factors -Descriptions of novel molecular biological and cytogenetic methods for genomic analysis