The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs.

[1]  E. Vivés,et al.  SUMOylation of the inducible (c-Fos:c-Jun)/AP-1 transcription complex occurs on target promoters to limit transcriptional activation , 2014, Oncogene.

[2]  John M. Ashton,et al.  Targeting Aberrant Glutathione Metabolism to Eradicate Human Acute Myelogenous Leukemia Cells* , 2013, The Journal of Biological Chemistry.

[3]  R. Nisticò,et al.  SUMO: a (Oxidative) Stressed Protein , 2013, NeuroMolecular Medicine.

[4]  S. Muller,et al.  The SUMO system: a master organizer of nuclear protein assemblies , 2013, Chromosoma.

[5]  A. Dejean,et al.  Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation , 2013, Genome research.

[6]  F. Melchior,et al.  Sumoylation: a regulatory protein modification in health and disease. , 2013, Annual review of biochemistry.

[7]  Benjamin J. Raphael,et al.  Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. , 2013, The New England journal of medicine.

[8]  D. Durocher,et al.  Regulation of DNA damage responses by ubiquitin and SUMO. , 2013, Molecular cell.

[9]  John M. Ashton,et al.  BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells. , 2013, Cell stem cell.

[10]  M. Matunis,et al.  SUMO: a multifaceted modifier of chromatin structure and function. , 2013, Developmental cell.

[11]  W. Paschen,et al.  Small ubiquitin‐like modifier 1–3 is activated in human astrocytic brain tumors and is required for glioblastoma cell survival , 2013, Cancer science.

[12]  K. Block,et al.  Aiding and abetting roles of NOX oxidases in cellular transformation , 2012, Nature Reviews Cancer.

[13]  J. Matés,et al.  Oxidative stress in apoptosis and cancer: an update , 2012, Archives of Toxicology.

[14]  Yuxin Tang,et al.  Anacardic acid (6-pentadecylsalicylic acid) induces apoptosis of prostate cancer cells through inhibition of androgen receptor and activation of p53 signaling. , 2012, Chinese journal of cancer research = Chung-kuo yen cheng yen chiu.

[15]  S. Weis,et al.  SUMOylation in carcinogenesis. , 2012, Cancer letters.

[16]  Ji Luo,et al.  A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis , 2012, Science.

[17]  E. Estey,et al.  Continuing medical education activity in American Journal of Hematology , 2011 .

[18]  J. Tamburini,et al.  High levels of CD34+CD38low/−CD123+ blasts are predictive of an adverse outcome in acute myeloid leukemia: a Groupe Ouest-Est des Leucémies Aiguës et Maladies du Sang (GOELAMS) study , 2011, Haematologica.

[19]  R. Darley,et al.  Do reactive oxygen species play a role in myeloid leukemias? , 2011, Blood.

[20]  S. Hansen,et al.  Simultaneous determination of cytosine arabinoside, daunorubicin and etoposide in human plasma. , 2010, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[21]  B. Raught,et al.  PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3. , 2010, Cancer cell.

[22]  J. Manley,et al.  SUMO functions in constitutive transcription and during activation of inducible genes in yeast. , 2010, Genes & development.

[23]  L. Gros,et al.  A Crucial Role for Infected-Cell/Antibody Immune Complexes in the Enhancement of Endogenous Antiviral Immunity by Short Passive Immunotherapy , 2010, PLoS pathogens.

[24]  Bart Barlogie,et al.  The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome. , 2010, Blood.

[25]  Kate S. Carroll,et al.  Orchestrating redox signaling networks through regulatory cysteine switches. , 2010, ACS chemical biology.

[26]  Minoru Yoshida,et al.  Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. , 2009, Chemistry & biology.

[27]  D. Tempé,et al.  SUMO under stress. , 2008, Biochemical Society transactions.

[28]  F. Melchior,et al.  Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes. , 2006, Molecular cell.

[29]  F. Moreau-Gachelin Lessons from models of murine erythroleukemia to acute myeloid leukemia (AML): proof-of-principle of co-operativity in AML. , 2006, Haematologica.

[30]  Martin Kuiper,et al.  BiNGO: a Cytoscape plugin to assess overrepresentation of Gene Ontology categories in Biological Networks , 2005, Bioinform..

[31]  Gordon K. Smyth,et al.  limma: Linear Models for Microarray Data , 2005 .

[32]  D. Gewirtz,et al.  A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. , 1999, Biochemical pharmacology.

[33]  E. Solary,et al.  Increased gadd153 messenger RNA level is associated with apoptosis in human leukemic cells treated with etoposide. , 1997, Cancer research.

[34]  G. Laurent,et al.  Daunorubicin-induced internucleosomal DNA fragmentation in acute myeloid cell lines. , 1996, Leukemia.

[35]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .