mTOR inhibitor INK128 promotes wound healing by regulating MDSCs
暂无分享,去创建一个
[1] M. Martinez-Fierro,et al. Myeloid-Derived Suppressor Cells Show Different Frequencies in Diabetics and Subjects with Arterial Hypertension , 2019, Journal of diabetes research.
[2] Huicui Meng,et al. Increased Adiposity Enhances the Accumulation of MDSCs in the Tumor Microenvironment and Adipose Tissue of Pancreatic Tumor-Bearing Mice and in Immune Organs of Tumor-Free Hosts , 2019, Nutrients.
[3] J. Steinbach,et al. Second Generation mTOR Inhibitors as a Double-Edged Sword in Malignant Glioma Treatment , 2019, International journal of molecular sciences.
[4] M. Xiang,et al. mTOR: A double‐edged sword for diabetes , 2019, Journal of leukocyte biology.
[5] Y. Kanda,et al. Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction. , 2019, Osteoarthritis and cartilage.
[6] Satish Patel,et al. Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[7] L. Ding,et al. mTOR inhibitor INK128 attenuates systemic lupus erythematosus by regulating inflammation-induced CD11b+Gr1+ cells. , 2019, Biochimica et biophysica acta. Molecular basis of disease.
[8] A. E. Sousa,et al. MDSCs in infectious diseases: regulation, roles, and readjustment , 2018, Cancer Immunology, Immunotherapy.
[9] Jie Tian,et al. Roles of Myeloid-Derived Suppressor Cell Subpopulations in Autoimmune Arthritis , 2018, Front. Immunol..
[10] H. Xiong,et al. Arctigenin Ameliorates Inflammation by Regulating Accumulation and Functional Activity of MDSCs in Endotoxin Shock , 2018, Inflammation.
[11] Yayi Hou,et al. mTOR inhibitor INK128 attenuates dextran sodium sulfate‐induced colitis by promotion of MDSCs on Treg cell expansion , 2018, Journal of cellular physiology.
[12] Q. Tan,et al. Wnt7a promotes wound healing by regulation of angiogenesis and inflammation: Issues on diabetes and obesity. , 2018, Journal of dermatological science.
[13] K. Lalić,et al. mTOR Inhibitor Therapy and Metabolic Consequences: Where Do We Stand? , 2018, Oxidative medicine and cellular longevity.
[14] Thomas D. Schmittgen,et al. CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128 , 2018, Oncotarget.
[15] A. Palmer,et al. The Role of Macrophages in Acute and Chronic Wound Healing and Interventions to Promote Pro-wound Healing Phenotypes , 2018, Front. Physiol..
[16] H. Raslan,et al. CD33+ HLA-DR– Myeloid-Derived Suppressor Cells Are Increased in Frequency in the Peripheral Blood of Type1 Diabetes Patients with Predominance of CD14+ Subset , 2018, Open access Macedonian journal of medical sciences.
[17] R. Z. Murray,et al. Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing , 2017, International journal of molecular sciences.
[18] Katherine A. Gallagher,et al. Macrophage-Mediated Inflammation in Normal and Diabetic Wound Healing , 2017, The Journal of Immunology.
[19] L. Ding,et al. Exosomal miR‐146a Contributes to the Enhanced Therapeutic Efficacy of Interleukin‐1β‐Primed Mesenchymal Stem Cells Against Sepsis , 2017, Stem cells.
[20] Mikaël M. Martino,et al. Promoting tissue regeneration by modulating the immune system. , 2017, Acta biomaterialia.
[21] Yan Zhang,et al. Accumulation of myeloid-derived suppressor cells (MDSCs) induced by low levels of IL-6 correlates with poor prognosis in bladder cancer , 2017, Oncotarget.
[22] D. Sabatini,et al. mTOR Signaling in Growth, Metabolism, and Disease , 2017, Cell.
[23] T. Zhu,et al. The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury , 2017, Cell Death & Disease.
[24] Bin Guo,et al. Hyaluronan oligosaccharides promote diabetic wound healing by increasing angiogenesis , 2016, Pharmacological reports : PR.
[25] D. Edwards,et al. Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation , 2016, Nature Cell Biology.
[26] A. Doğan,et al. Boron promotes streptozotocin-induced diabetic wound healing: roles in cell proliferation and migration, growth factor expression, and inflammation , 2016, Molecular and Cellular Biochemistry.
[27] T. Wynn,et al. Macrophages in Tissue Repair, Regeneration, and Fibrosis. , 2016, Immunity.
[28] Yang Zhao,et al. mTOR masters monocytic myeloid-derived suppressor cells in mice with allografts or tumors , 2016, Scientific Reports.
[29] T. Weichhart,et al. Regulation of innate immune cell function by mTOR , 2015, Nature Reviews Immunology.
[30] J. Buse,et al. Myeloid-derived suppressor cells are increased in frequency but not maximally suppressive in peripheral blood of Type 1 Diabetes Mellitus patients. , 2014, Clinical immunology.
[31] M. Sade-Feldman,et al. Tumor necrosis factor-α blocks differentiation and enhances suppressive activity of immature myeloid cells during chronic inflammation. , 2013, Immunity.
[32] James A. Hutchinson,et al. IFN-γ-induced iNOS expression in mouse regulatory macrophages prolongs allograft survival in fully immunocompetent recipients. , 2013, Molecular therapy : the journal of the American Society of Gene Therapy.
[33] K. Maruyama,et al. Topical simvastatin accelerates wound healing in diabetes by enhancing angiogenesis and lymphangiogenesis. , 2012, The American journal of pathology.
[34] Nicholas T. Ingolia,et al. The translational landscape of mTOR signalling steers cancer initiation and metastasis , 2012, Nature.
[35] S. Leibovich,et al. Regulation of Macrophage Polarization and Wound Healing. , 2012, Advances in wound care.
[36] T. Koh,et al. Dysregulation of monocyte/macrophage phenotype in wounds of diabetic mice. , 2011, Cytokine.
[37] J. Bottomley,et al. Economic costs of diabetes in the US in 2007 — Implications for Europe , 2008 .
[38] Vincent Falanga,et al. Wound healing and its impairment in the diabetic foot , 2005, The Lancet.
[39] A. Bartolomé,et al. Role of the mammalian target of rapamycin (mTOR) complexes in pancreatic β-cell mass regulation. , 2014, Vitamins and hormones.
[40] Shuhui He,et al. Electrospun fibers with plasmid bFGF polyplex loadings promote skin wound healing in diabetic rats. , 2012, Molecular pharmaceutics.
[41] J. Leahy. Economic Costs of Diabetes in the U.S. in 2007 , 2008 .
[42] Hilde van der Togt,et al. Publisher's Note , 2003, J. Netw. Comput. Appl..