Preterm infants' limb-pose estimation from depth images using convolutional neural networks

Preterm infants' limb-pose estimation is a crucial but challenging task, which may improve patients' care and facilitate clinicians in infant's movements monitoring. Work in the literature either provides approaches to whole-body segmentation and tracking, which, however, has poor clinical value, or retrieve a posteriori limb pose from limb segmentation, increasing computational costs and introducing inaccuracy sources. In this paper, we address the problem of limb-pose estimation under a different point of view. We proposed a 2D fully-convolutional neural network for roughly detecting limb joints and joint connections, followed by a regression convolutional neural network for accurate joint and joint-connection position estimation. Joints from the same limb are then connected with a maximum bipartite matching approach. Our analysis does not require any prior modeling of infants' body structure, neither any manual interventions. For developing and testing the proposed approach, we built a dataset of four videos (video length = 90 s) recorded with a depth sensor in a neonatal intensive care unit (NICU) during the actual clinical practice, achieving median root mean square distance [pixels] of 10.790 (right arm), 10.542 (left arm), 8.294 (right leg), 11.270 (left leg) with respect to the ground-truth limb pose. The idea of estimating limb pose directly from depth images may represent a future paradigm for addressing the problem of preterm-infants' movement monitoring and offer all possible support to clinicians in NICUs.

[1]  Yingli Tian,et al.  Privacy Preserving Automatic Fall Detection for Elderly Using RGBD Cameras , 2012, ICCHP.

[2]  Y. Schutz,et al.  Energy Balance, Physical Activity, and Thermogenic Effect of Feeding in Premature Infants , 1986, Pediatric Research.

[3]  Sergio Escalera,et al.  Graph cuts optimization for multi-limb human segmentation in depth maps , 2012, 2012 IEEE Conference on Computer Vision and Pattern Recognition.

[4]  Emanuele Frontoni,et al.  Non-Contact Monitoring of Preterm Infants Using RGB-D Camera , 2015 .

[5]  Danail Stoyanov,et al.  Articulated Multi-Instrument 2-D Pose Estimation Using Fully Convolutional Networks , 2018, IEEE Transactions on Medical Imaging.

[6]  Marcin Grzegorzek,et al.  Detection of Infantile Movement Disorders in Video Data Using Deformable Part-Based Model , 2018, Sensors.

[7]  Danail Stoyanov,et al.  Deep Learning Based Robotic Tool Detection and Articulation Estimation With Spatio-Temporal Layers , 2019, IEEE Robotics and Automation Letters.

[8]  L. Radlinger,et al.  Inter- and intra-observer agreement of Prechtl's method on the qualitative assessment of general movements in preterm, term and young infants. , 2011, Early human development.

[9]  Z. Bhutta,et al.  Monitoring postnatal growth of preterm infants: present and future. , 2016, The American journal of clinical nutrition.

[10]  Bernt Schiele,et al.  Learning Non-maximum Suppression , 2017, 2017 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[11]  Øyvind Stavdahl,et al.  Weakly supervised motion segmentation with particle matching , 2015, Comput. Vis. Image Underst..

[12]  G Carrault,et al.  Video and audio processing in paediatrics: a review , 2019, Physiological measurement.

[13]  Luca Romeo,et al.  An instrumental approach for monitoring physical exercises in a visual markerless scenario: A proof of concept. , 2018, Journal of biomechanics.

[14]  Michael Arens,et al.  Learning an Infant Body Model from RGB-D Data for Accurate Full Body Motion Analysis , 2018, MICCAI.

[15]  O. M. Aamo,et al.  An Optical Flow-Based Method to Predict Infantile Cerebral Palsy , 2012, IEEE Transactions on Neural Systems and Rehabilitation Engineering.

[16]  Melissa E. Libertus,et al.  The General Movement Assessment Helps Us to Identify Preterm Infants at Risk for Cognitive Dysfunction , 2016, Front. Psychol..

[17]  Yaser Sheikh,et al.  OpenPose: Realtime Multi-Person 2D Pose Estimation Using Part Affinity Fields , 2018, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[18]  G Cioni,et al.  Qualitative changes of general movements in preterm infants with brain lesions. , 1990, Early human development.

[19]  Ruth Guinsburg,et al.  Neonatal procedural pain can be assessed by computer software that has good sensitivity and specificity to detect facial movements , 2015, Acta paediatrica.

[20]  D. Sternad,et al.  Quantifying Movement in Preterm Infants Using Photoplethysmography , 2018, Annals of Biomedical Engineering.

[21]  Thomas Brox,et al.  U-Net: Convolutional Networks for Biomedical Image Segmentation , 2015, MICCAI.

[22]  Ronald M. Aarts,et al.  Unobtrusive sleep state measurements in preterm infants - A review. , 2017, Sleep medicine reviews.

[23]  Alexander Refsum Jensenius,et al.  Using computer-based video analysis in the study of fidgety movements. , 2009, Early human development.