[Universal definition of the myocardial infarction].

Task Force Members: Chairpersons: Kristian Thygesen (Denmark)*, Joseph S. Alpert (USA)*, Harvey D. White (New Zealand)* Biomarker Group: Allan S. Jaffe, Co-ordinator (USA), Fred S. Apple (USA), Marcello Galvani (Italy), Hugo A. Katus (Germany), L. Kristin Newby (USA), Jan Ravkilde (Denmark) ECG Group: Bernard Chaitman, Co-ordinator (USA), Peter M. Clemmensen (Denmark), Mikael Dellborg (Sweden), Hanoch Hod (Israel), Pekka Porela (Finland) Imaging Group: Richard Underwood, Co-ordinator (UK), Jeroen J. Bax (The Netherlands) George A. Beller (USA), Robert Bonow (USA), Ernst E. Van Der Wall (The Netherlands) Intervention Group: Jean-Pierre Bassand, Co-ordinator (France), William Wijns, Co-ordinator (Belgium), T. Bruce Ferguson (USA), Philippe G. Steg (France), Barry F. Uretsky (USA), David O. Williams (USA) Clinical Investigation Group: Paul W. Armstrong, Co-ordinator (Canada), Elliott M. Antman (USA), Keith A. Fox (UK), Christian W. Hamm (Germany), E. Magnus Ohman (USA), Maarten L. Simoons (The Netherlands) Global Perspective Group: Philip A. Poole-Wilson, Co-ordinator (UK), Enrique P. Gurfinkel (Argentina), José-Luis Lopez-Sendon (Spain), Prem Pais (India), Shanti Mendis‡ (Switzerland), Jun-Ren Zhu (China) Implementation Group: Lars C. Wallentin Co-ordinator (Sweden), Francisco Fernández-Avilés (Spain), Kim M. Fox (UK), Alexander N. Parkhomenko (Ukraine), Silvia G. Priori (Italy), Michal Tendera (Poland), Liisa-Maria Voipio-Pulkki (Finland)

[1]  R. Bonow,et al.  Troponin I elevation and cardiac events after percutaneous coronary intervention. , 2003, American heart journal.

[2]  H. Hod,et al.  Q wave and Non-Q wave myocardial infarction after thrombolysis. , 1995, Journal of the American College of Cardiology.

[3]  W R Dassen,et al.  Value of the electrocardiogram in localizing the occlusion site in the left anterior descending coronary artery in acute anterior myocardial infarction. , 1999, Journal of the American College of Cardiology.

[4]  E. W. Hancock,et al.  Recommendations for the standardization and interpretation of the electrocardiogram. Part I: The electrocardiogram and its technology. A scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Car , 2007, Heart rhythm.

[5]  K. Eagle,et al.  The new definition of myocardial infarction: diagnostic and prognostic implications in patients with acute coronary syndromes. , 2002, Archives of internal medicine.

[6]  L. Haramati,et al.  CT detection of acute myocardial infarction. , 2004, AJR. American journal of roentgenology.

[7]  A. Jaffe,et al.  It's time for a change to a troponin standard. , 2000, Circulation.

[8]  M. Burritt,et al.  Timing of peak troponin T and creatine kinase-MB elevations after percutaneous coronary intervention. , 2004, Chest.

[9]  F. Apple,et al.  Cardiac troponin and creatine kinase MB monitoring during in-hospital myocardial reinfarction. , 2005, Clinical chemistry.

[10]  R. Califf,et al.  Patients with prolonged ischemic chest pain and presumed-new left bundle branch block have heterogeneous outcomes depending on the presence of ST-segment changes. , 2005, Journal of the American College of Cardiology.

[11]  M. Burritt,et al.  Baseline troponin level: key to understanding the importance of post-PCI troponin elevations. , 2006, European heart journal.

[12]  J. Ornato,et al.  Impact of the troponin standard on the prevalence of acute myocardial infarction. , 2003, American heart journal.

[13]  Elmar Spuentrup,et al.  Assessment of myocardial viability in reperfused acute myocardial infarction using 16-slice computed tomography in comparison to magnetic resonance imaging. , 2005, Journal of the American College of Cardiology.

[14]  A. Buda.  The role of echocardiography in the evaluation of mechanical complications of acute myocardial infarction. , 1991, Circulation.

[15]  angesichts der Corona-Pandemie,et al.  UPDATE , 1973, The Lancet.

[16]  A. Wu,et al.  Quality Specifications for Cardiac Troponin Assays , 2001, Clinical chemistry and laboratory medicine.

[17]  O. Simonetti,et al.  Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. , 1999, Circulation.

[18]  Hugo A. Katus,et al.  Myocardial infarction redefined--a consensus document of The Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. , 2000, European heart journal.

[19]  N. Moatti,et al.  Cardiac troponin I: Its contribution to the diagnosis of perioperative myocardial infarction and various complications of cardiac surgery , 2001, Critical care medicine.

[20]  S. Petersen,et al.  Relationship of irreversible myocardial injury to troponin I and creatine kinase-MB elevation after coronary artery bypass surgery: insights from cardiovascular magnetic resonance imaging. , 2005, Journal of the American College of Cardiology.

[21]  Deepak L. Bhatt,et al.  Clinical end point definitions after percutaneous coronary intervention and their relationship to late mortality: an assessment by attributable risk , 2005, Heart.

[22]  S. Kathiresan,et al.  A comparison of cardiac troponin T and creatine kinase-MB for patient evaluation after cardiac surgery. , 2002, Journal of the American College of Cardiology.

[23]  Lippincott Williams Wilkins,et al.  ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction , 2004 .

[24]  David P Miller,et al.  Long-term mortality benefit with abciximab in patients undergoing percutaneous coronary intervention. , 2001, Journal of the American College of Cardiology.

[25]  R. Kim,et al.  Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study , 2003, The Lancet.

[26]  D Freimark,et al.  Acute myocardial infarction with isolated ST-segment elevation in posterior chest leads V7-9: "hidden" ST-segment elevations revealing acute posterior infarction. , 1999, Journal of the American College of Cardiology.

[27]  R. Asinger,et al.  ST-segment elevation in conditions other than acute myocardial infarction. , 2003, The New England journal of medicine.

[28]  J. Agarwal,et al.  Importance of posterior chest leads in patients with suspected myocardial infarction, but nondiagnostic, routine 12-lead electrocardiogram. , 1999, The American journal of cardiology.

[29]  S. Petersen,et al.  Troponin Elevation After Percutaneous Coronary Intervention Directly Represents the Extent of Irreversible Myocardial Injury: Insights From Cardiovascular Magnetic Resonance Imaging , 2005, Circulation.

[30]  M. Simoons,et al.  Minor Myocardial Damage and Prognosis: Are Spontaneous and Percutaneous Coronary Intervention–Related Events Different? , 2002, Circulation.

[31]  M. Verani,et al.  Assessment of myocardial viability with 99mTc sestamibi in patients undergoing cardiac transplantation. A scintigraphic/pathological study. , 1996, Circulation.

[32]  P M Rautaharju,et al.  The Novacode criteria for classification of ECG abnormalities and their clinically significant progression and regression. , 1998, Journal of electrocardiology.

[33]  J. Guermonprez,et al.  Troponin T levels in detection of perioperative myocardial infarction after coronary artery bypass surgery. , 2004, Clinical laboratory.

[34]  D. Berman,et al.  An economic analysis of an aggressive diagnostic strategy with single photon emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department patients who present with chest pain but nondiagnostic electrocardiograms: Results from a randomized trial. , 2000, Annals of emergency medicine.

[35]  C. Gustavsson,et al.  Troponin must be measured before and after PCI to diagnose procedure-related myocardial injury , 2004, Scandinavian cardiovascular journal : SCJ.

[36]  H. Tunstall-Pedoe,et al.  Redefinition of Myocardial Infarction: Prospective Evaluation in the Community , 2006, Circulation.

[37]  G. Ferns,et al.  Minor myocardial injury after elective uncomplicated successful PTCA with or without stenting: Detection by cardiac troponins , 2001, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[38]  J. López-Sendón,et al.  Electrocardiographic findings in acute right ventricular infarction: sensitivity and specificity of electrocardiographic alterations in right precordial leads V4R, V3R, V1, V2, and V3. , 1985, Journal of the American College of Cardiology.

[39]  S. Hill,et al.  Determination of Troponin I Release After CABG Surgery , 2005, Journal of cardiac surgery.

[40]  E. Schenk,et al.  A Solid Angle Analysis of the Epicardial Ischemic TQ‐ST Deflection in the Pig: A Theoretical and Experimental Study , 1978, Circulation research.

[41]  J. Lima,et al.  Myocardial viability assessment by contrast-enhanced magnetic resonance imaging. , 2003, Journal of the American College of Cardiology.

[42]  M. Josephson,et al.  Usefulness of ST-segment elevation in lead III exceeding that of lead II for identifying the location of the totally occluded coronary artery in inferior wall myocardial infarction. , 1998, The American journal of cardiology.

[43]  A. Ekmekci,et al.  Angina pectoris. V. Giant R and receding S wave in myocardial ischemia and certain nonischemic conditions. , 1961, The American journal of cardiology.

[44]  M. Jerosch-Herold,et al.  Infarct extent by MRI correlates with peak serum troponin level in the canine model. , 2004, The Journal of surgical research.

[45]  C. Visser,et al.  Usefulness of two-dimensional echocardiography for immediate detection of myocardial ischemia in the emergency room. , 1990, The American journal of cardiology.

[46]  C. Kramer,et al.  Cardiovascular magnetic resonance: Structure, function, perfusion, and viability , 2005, Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology.

[47]  H. Katus,et al.  Usefulness of real-time myocardial perfusion imaging in the evaluation of patients with first time chest pain. , 2004, The American journal of cardiology.

[48]  V. Salomaa,et al.  A new definition for myocardial infarction: what difference does it make? , 2005, European heart journal.

[49]  R. Holland,et al.  Precordial and Epicardial Surface Potentials during Myocardial Ischemia in the Pig: A THEORETICAL AND EXPERIMENTAL ANALYSIS OF THE TQ AND ST SEGMENTS , 1975, Circulation research.

[50]  J. Ioannidis,et al.  Mortality risk conferred by small elevations of creatine kinase-MB isoenzyme after percutaneous coronary intervention. , 2003, Journal of the American College of Cardiology.

[51]  M. Verani,et al.  Criteria for the accurate interpretation of changes in left ventricular ejection fraction and cardiac volumes as assessed by rest and exercise gated radionuclide angiography. , 1991, Journal of the American College of Cardiology.

[52]  G. Hillis,et al.  Relationship Between Postoperative Cardiac Troponin I Levels and Outcome of Cardiac Surgery , 2006, Circulation.

[53]  A. Jaffe,et al.  Validation of the 99th percentile cutoff independent of assay imprecision (CV) for cardiac troponin monitoring for ruling out myocardial infarction. , 2005, Clinical chemistry.

[54]  L Goldman,et al.  Multiple gated cardiac blood pool imaging for left ventricular ejection fraction: validation of the technique and assessment of variability. , 1979, The American journal of cardiology.

[55]  J P Ornato,et al.  Comprehensive strategy for the evaluation and triage of the chest pain patient. , 1997, Annals of emergency medicine.

[56]  A. Wu,et al.  Evaluation of imprecision for cardiac troponin assays at low-range concentrations. , 2004, Clinical chemistry.

[57]  S. Kaul,et al.  Importance of Two‐dimensional Echocardiographic Assessment of Left Ventricular Systolic Function in Patients Presenting to the Emergency Room With Cardiac‐Related Symptoms , 1991, Circulation.

[58]  H. White,et al.  Clinical implications of the new definition of myocardial infarction , 2003, Heart.

[59]  J. Herrmann.  Peri-procedural myocardial injury: 2005 update. , 2005, European heart journal.

[60]  T. Nageh,et al.  Comparison of cardiac troponin T and I and CK-MB for the detection of minor myocardial damage during interventional cardiac procedures , 2000, Annals of clinical biochemistry.

[61]  M. Verani,et al.  Assessment of myocardial viability with 99mTc-sestamibi tomography before coronary bypass graft surgery: correlation with histopathology and postoperative improvement in cardiac function. , 1997, Circulation.

[62]  R. Giubbini,et al.  Single-point cardiac troponin T at coronary care unit discharge after myocardial infarction correlates with infarct size and ejection fraction. , 2002, Clinical chemistry.

[63]  N. Nagajothi,et al.  Biomarkers in acute cardiac disease. , 2006, Journal of the American College of Cardiology.

[64]  A. Jaffe,et al.  National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biochemical markers of acute coronary syndromes. , 2007, Clinical chemistry.

[65]  K. Saeian,et al.  Ultrasonic tissue characterization for diagnosis of acute myocardial infarction in the coronary care unit. , 1994, The American journal of cardiology.

[66]  R. Ideker,et al.  Correlation of Postmortem Anatomic Findings with Electrocardiographic Changes in Patients with Myocardial Infarction: Retrospective Study of Patients with Typical Anterior and Posterior Infarcts , 1977, Circulation.

[67]  H. Katus,et al.  Troponin T concentrations 72 hours after myocardial infarction as a serological estimate of infarct size , 2002, Heart.

[68]  L. Horan,et al.  Significance of the Diagnostic Q Wave of Myocardial Infarction , 1971, Circulation.

[69]  Fred S Apple,et al.  National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: Clinical characteristics and utilization of biochemical markers in acute coronary syndromes. , 2007, Circulation.

[70]  P M Rautaharju,et al.  Comparison of the various electrocardiographic scoring codes for estimating anatomically documented sizes of single and multiple infarcts of the left ventricle. , 1998, The American journal of cardiology.

[71]  L. Holmvang,et al.  Use of biochemical markers of infarction for diagnosing perioperative myocardial infarction and early graft occlusion after coronary artery bypass surgery. , 2002, Chest.

[72]  A. Jaffe.  Chasing troponin: how low can you go if you can see the rise? , 2006, Journal of the American College of Cardiology.

[73]  H. Helenius,et al.  Epidemiological classification of acute myocardial infarction: time for a change? , 1999, European heart journal.

[74]  B. Gersh.  Redefinition of Myocardial Infarction: Prospective Evaluation in the Community , 2007 .

[75]  A. Jaffe,et al.  Assessing the requirement for the 6-hour interval between specimens in the American Heart Association Classification of Myocardial Infarction in Epidemiology and Clinical Research Studies. , 2006, Clinical chemistry.

[76]  B. Chaitman,et al.  Increased mortality after coronary artery bypass graft surgery is associated with increased levels of postoperative creatine kinase-myocardial band isoenzyme release: results from the GUARDIAN trial. , 2001, Journal of the American College of Cardiology.

[77]  Ric,et al.  Electrocardiographic Diagnosis of Evolving Acute Myocardial Infarction in the Presence of Left Bundle-Branch Block , 1996 .

[78]  R. Hendel,et al.  Myocardial perfusion imaging for evaluation and triage of patients with suspected acute cardiac ischemia: a randomized controlled trial. , 2002, JAMA.

[79]  Mark E Josephson,et al.  Use of the electrocardiogram in acute myocardial infarction. , 2003, The New England journal of medicine.

[80]  P. Macfarlane.  Age, sex, and the ST amplitude in health and disease. , 2001, Journal of electrocardiology.

[81]  E. Topol,et al.  Association between CK-MB elevation after percutaneous or surgical revascularization and three-year mortality. , 2002, Journal of the American College of Cardiology.

[82]  R. Kim,et al.  Visualization of Discrete Microinfarction After Percutaneous Coronary Intervention Associated With Mild Creatine Kinase-MB Elevation , 2001, Circulation.