The Inhibitory Receptor FcγRII Reduces Joint Inflammation and Destruction in Experimental Immune Complex-Mediated Arthritides Not Only by Inhibition of FcγRI/III but Also by Efficient Clearance and Endocytosis of Immune Complexes

[1]  R. Schmidt,et al.  C5a anaphylatoxin is a major regulator of activating versus inhibitory FcgammaRs in immune complex-induced lung disease. , 2002, The Journal of clinical investigation.

[2]  Sang-Oh Yoon,et al.  Sustained Production of H2O2Activates Pro-matrix Metalloproteinase-2 through Receptor Tyrosine Kinases/Phosphatidylinositol 3-Kinase/NF-κB Pathway* , 2002, The Journal of Biological Chemistry.

[3]  C. Nielsen,et al.  Complement’s participation in acquired immunity , 2002, Journal of leukocyte biology.

[4]  M. Walport,et al.  Complement Activation Selectively Potentiates the Pathogenicity of the IgG2b and IgG3 Isotypes of a High Affinity Anti-Erythrocyte Autoantibody , 2002, The Journal of experimental medicine.

[5]  G. van Ommen,et al.  FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. , 2002, Immunity.

[6]  Ralph Weissleder,et al.  Arthritis critically dependent on innate immune system players. , 2002, Immunity.

[7]  S. Verbeek,et al.  Role of Activatory FcγRI and FcγRIII and Inhibitory FcγRII in Inflammation and Cartilage Destruction during Experimental Antigen-Induced Arthritis , 2001 .

[8]  J. Cambier,et al.  FcgammaRIIB-mediated inhibition of T-cell receptor signal transduction involves the phosphorylation of SH2-containing inositol 5-phosphatase (SHIP), dephosphorylation of the linker of activated T-cells (LAT) and inhibition of calcium mobilization. , 2001, Biochemical Society Transactions.

[9]  M. Ernst,et al.  Human MO subsets as defined by expression of CD64 and CD16 differ in phagocytic activity and generation of oxygen intermediates. , 2000, Immunobiology.

[10]  M. Ehlers,et al.  CR3: a general purpose adhesion-recognition receptor essential for innate immunity. , 2000, Microbes and infection.

[11]  R. Lynch.  Regulatory roles for FcγRIII (CD16) and FcγRII (CD32) in the development of T‐ and B‐lineage lymphoid cells , 2000, Journal of leukocyte biology.

[12]  R. Schmidt,et al.  Mouse FcγRII is a negative regulator of FcγRIII in IgG immune complex‐triggered inflammation but not in autoantibody‐induced hemolysis , 2000 .

[13]  J. Köhl,et al.  A Codominant Role of FcγRI/III and C5aR in the Reverse Arthus Reaction1 , 2000, The Journal of Immunology.

[14]  J. V. van Meurs,et al.  Active matrix metalloproteinases are present in cartilage during immune complex-mediated arthritis: a pivotal role for stromelysin-1 in cartilage destruction. , 1999, Journal of immunology.

[15]  J. V. van Meurs,et al.  Kinetics of aggrecanase- and metalloproteinase-induced neoepitopes in various stages of cartilage destruction in murine arthritis. , 1999, Arthritis and rheumatism.

[16]  Leslie J. Crofford,et al.  Primer on the Rheumatic Diseases , 1999 .

[17]  N. Thompson,et al.  The Cytoplasmic Region of Mouse FcγRIIb1, but Not FcγRIIb2, Binds Phospholipid Membranes† , 1999 .

[18]  T. Yoshino,et al.  Deletion of Fcγ Receptor IIB Renders H-2b Mice Susceptible to Collagen-induced Arthritis , 1999, The Journal of experimental medicine.

[19]  T. K. van den Berg,et al.  Murine IgG1 complexes trigger immune effector functions predominantly via Fc gamma RIII (CD16). , 1998, Journal of immunology.

[20]  W. B. van den Berg,et al.  Phagocytic synovial lining cells regulate acute and chronic joint inflammation after antigenic exacerbation of smouldering experimental murine arthritis. , 1998, Journal of Rheumatology.

[21]  J. V. van Meurs,et al.  Interleukin-1 receptor antagonist prevents expression of the metalloproteinase-generated neoepitope VDIPEN in antigen-induced arthritis. , 1998, Arthritis and rheumatism.

[22]  T. Cawston.  Matrix metalloproteinases and TIMPs: properties and implications for the rheumatic diseases. , 1998, Molecular medicine today.

[23]  H. Ronday,et al.  Modified proenzymes as artificial substrates for proteolytic enzymes: colorimetric assay of bacterial collagenase and matrix metalloproteinase activity using modified pro-urokinase. , 1997, The Biochemical journal.

[24]  W. Fridman,et al.  Regulation of ITAM Signaling by Specific Sequences in Ig-β B Cell Antigen Receptor Subunit* , 1996, The Journal of Biological Chemistry.

[25]  W. B. van den Berg,et al.  Phagocytic lining cells determine local expression of inflammation in type II collagen-induced arthritis. , 1996, Arthritis and rheumatism.

[26]  M. Ono,et al.  Augmented humoral and anaphylactic responses in FcγRII-deficient mice , 1996, Nature.

[27]  J. Weidner,et al.  VDIPEN, a metalloproteinase-generated neoepitope, is induced and immunolocalized in articular cartilage during inflammatory arthritis. , 1995, The Journal of clinical investigation.

[28]  J. Ravetch.  Fc receptors: Rubor redux , 1994, Cell.

[29]  N. Rooijen,et al.  Phagocytic synovial lining cells in experimentally induced chronic arthritis: down-regulation of synovitis by CL2MDP-liposomes , 1994, Rheumatology International.

[30]  W. Fridman,et al.  Distinct intracytoplasmic sequences are required for endocytosis and phagocytosis via murine Fc gamma RII in mast cells. , 1993, International immunology.

[31]  W. B. van den Berg,et al.  In vivo role of phagocytic synovial lining cells in onset of experimental arthritis. , 1993, The American journal of pathology.

[32]  M. Goebeler,et al.  Expression and complex assembly of calcium‐binding proteins MRP8 and MRP14 during differentiation of murine myelomonocytic cells , 1993, Journal of leukocyte biology.

[33]  W. V. D. Berg,et al.  Cationic immune complex arthritis in mice--a new model. Synergistic effect of complement and interleukin-1. , 1992 .

[34]  H. Waldmann,et al.  Monoclonal antibodies as agents to reinduce tolerance in autoimmunity. , 1992, Journal of autoimmunity.

[35]  A. Ariza,et al.  Arthritis transferred by cells derived from pre-inflammatory rat synovium. , 1992, Journal of autoimmunity.

[36]  W. Fridman,et al.  Structural Bases of Fcγ Receptor Functions , 1992, Immunological reviews.

[37]  E. Bauer,et al.  Stromelysin expression regulates collagenase activation in human fibroblasts. Dissociable control of two metalloproteinases by interferon-gamma. , 1991, The Journal of biological chemistry.

[38]  J. Frey,et al.  Structural requirements of the cytoplasmic domains of the human macrophage Fcγ receptor IIa and B cell Fcγ receptor IIb2 for the endocytosis of immune complexes , 1991 .

[39]  I. Mellman,et al.  Expression of macrophage-lymphocyte Fc receptors in Madin-Darby canine kidney cells: polarity and transcytosis differ for isoforms with or without coated pit localization domains , 1989, The Journal of cell biology.

[40]  W. B. van den Berg,et al.  Allergic arthritis induced by cationic proteins: role of molecular weight. , 1989, Immunology.

[41]  I. Mellman,et al.  Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity , 1989, Cell.

[42]  T. Cooke.  Mechanisms of cartilage degradation: relation to choice of therapeutic agent. , 1985, Seminars in arthritis and rheumatism.

[43]  L. Putte,et al.  Quantitation of arthritis by99mTc-uptake measurements in the mouse knee-joint: correlation with histological joint inflammation scores , 1984, Agents and Actions.

[44]  M. Feldmann,et al.  Role of pro-inflammatory cytokines in rheumatoid arthritis , 2004, Springer Seminars in Immunopathology.

[45]  S. Verbeek,et al.  Coordinate expression of activating Fc gamma receptors I and III and inhibiting Fc gamma receptor type II in the determination of joint inflammation and cartilage destruction during immune complex-mediated arthritis. , 2003, Arthritis and rheumatism.

[46]  R. Strieter,et al.  Chemokines in rheumatoid arthritis , 2004, Springer Seminars in Immunopathology.

[47]  B. Bresnihan,et al.  Synovial tissue macrophage populations and articular damage in rheumatoid arthritis. , 1996, Arthritis and rheumatism.

[48]  N. Zvaifler.  Macrophages and the synovial lining. , 1995, Scandinavian journal of rheumatology. Supplement.