Characterisation of Clostridium difficile Hospital Ward–Based Transmission Using Extensive Epidemiological Data and Molecular Typing

A population-based study in Oxfordshire (UK) hospitals by Sarah Walker and colleagues finds that in an endemic setting with good infection control, ward-based contact cannot account for most new cases of Clostridium difficile infection.

[1]  T. Peto,et al.  Clostridium difficile Mixed Infection and Reinfection , 2011, Journal of Clinical Microbiology.

[2]  G. French,et al.  Diagnostic testing for Clostridium difficile: a comprehensive survey of laboratories in England. , 2011, The Journal of hospital infection.

[3]  M. Wilcox.  Laboratory diagnosis of Clostridium difficile infection: in a state of transition or confusion or both? , 2011, The Journal of hospital infection.

[4]  D. Pillai,et al.  Defining criteria to interpret multilocus variable-number tandem repeat analysis to aid Clostridium difficile outbreak investigation. , 2011, Journal of medical microbiology.

[5]  M. Wilcox,et al.  Reference assays for Clostridium difficile infection: one or two gold standards? , 2010, Journal of Clinical Pathology.

[6]  B. Limbago,et al.  Clostridium difficile in food and domestic animals: a new foodborne pathogen? , 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[7]  Joseph N S Eisenberg,et al.  How Infections Propagate After Point-Source Outbreaks: An Analysis of Secondary Norovirus Transmission , 2010, Epidemiology.

[8]  M. Wilcox,et al.  The potential for airborne dispersal of Clostridium difficile from symptomatic patients. , 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[9]  D. Gerding,et al.  Clinical Practice Guidelines for Clostridium difficile Infection in Adults: 2010 Update by the Society for Healthcare Epidemiology of America (SHEA) and the Infectious Diseases Society of America (IDSA) , 2010, Infection Control & Hospital Epidemiology.

[10]  P. Hawkey,et al.  Coexistence of Multiple Multilocus Variable-Number Tandem-Repeat Analysis Subtypes of Clostridium difficile PCR Ribotype 027 Strains within Fecal Specimens , 2010, Journal of Clinical Microbiology.

[11]  A. Charlett,et al.  Comparison of Nine Commercially Available Clostridium difficile Toxin Detection Assays, a Real-Time PCR Assay for C. difficile tcdB, and a Glutamate Dehydrogenase Detection Assay to Cytotoxin Testing and Cytotoxigenic Culture Methods , 2009, Journal of Clinical Microbiology.

[12]  J. Weese,et al.  Possible Seasonality of Clostridium difficile in Retail Meat, Canada , 2009, Emerging infectious diseases.

[13]  G. Dumyati,et al.  Rapid Molecular Characterization of Clostridium difficile and Assessment of Populations of C. difficile in Stool Specimens , 2009, Journal of Clinical Microbiology.

[14]  Richard Holliman,et al.  Diagnosis of Clostridium difficile infection by toxin detection kits: a systematic review. , 2008, The Lancet. Infectious diseases.

[15]  H. Maarleveld,et al.  Infection control measures to limit the spread of Clostridium difficile. , 2008, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[16]  Jane W. Marsh,et al.  Control of an outbreak of infection with the hypervirulent Clostridium difficile BI strain in a university hospital using a comprehensive "bundle" approach. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[17]  C. Donskey,et al.  Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[18]  L. Valiquette,et al.  Impact of a reduction in the use of high-risk antibiotics on the course of an epidemic of Clostridium difficile-associated disease caused by the hypervirulent NAP1/027 strain. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[19]  Stuart Johnson,et al.  An epidemic, toxin gene-variant strain of Clostridium difficile. , 2005, The New England journal of medicine.

[20]  Ken Dewar,et al.  A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. , 2005, The New England journal of medicine.

[21]  K. Sepkowitz,et al.  Risk Factors for Acquisition of Clostridium difficile–Associated Diarrhea among Outpatients at a Cancer Hospital , 2005, Infection Control & Hospital Epidemiology.

[22]  Martin Schumacher,et al.  How many infections are caused by patient-to-patient transmission in intensive care units?* , 2005, Critical care medicine.

[23]  E. Kuijper,et al.  Coexistence of multiple PCR-ribotype strains of Clostridium difficile in faecal samples limits epidemiological studies. , 2005, Journal of medical microbiology.

[24]  M. Wilcox,et al.  Role of antibody response in outcome of antibiotic-associated diarrhoea , 2001, The Lancet.

[25]  C. Kelly,et al.  Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. , 2000, The New England journal of medicine.

[26]  M. Samore,et al.  Primary symptomless colonisation by Clostridium difficile and decreased risk of subsequent diarrhoea , 1998, The Lancet.

[27]  M. Samore,et al.  Clostridium difficile colonization and diarrhea at a tertiary care hospital. , 1994, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[28]  S. Palmer,et al.  Incubation period, severity of disease, and infecting dose: evidence from a Salmonella outbreak. , 1992, American journal of epidemiology.

[29]  W. Stamm,et al.  Nosocomial acquisition of Clostridium difficile infection. , 1989, The New England journal of medicine.

[30]  L. Billard,et al.  Incubation period of AIDS in patients infected via blood transfusion , 1987, Nature.

[31]  H. Dupont,et al.  Typhoid fever: pathogenesis and immunologic control. , 1970, The New England journal of medicine.

[32]  H. J. Magnuson,et al.  INOCULATION SYPHILIS IN HUMAN VOLUNTEERS , 1956, Medicine.

[33]  William F. Hughes,et al.  Manson's Tropical Diseases , 1914, The Indian Medical Gazette.

[34]  L. Lemée,et al.  Multilocus sequence typing for Clostridium difficile. , 2010, Methods in molecular biology.

[35]  Alimuddin Zumla,et al.  Comprar Mansons Tropical Diseases, 22nd edition Expert Consult | Alimuddin I. Zumla | 9781416044703 | Saunders , 2009 .

[36]  J. Cooke,et al.  Clostridium difficile infection: how to deal with the problem , 2009 .

[37]  Alimuddin Zumla,et al.  Manson's Tropical Diseases, 21st Edition , 2003 .