Transferring patients for primary angioplasty: a retrospective analysis of 104 selected high risk patients with acute myocardial infarction

Objective To investigate the feasibility of primary coronary angioplasty as a treatment option in patients with acute myocardial infarction after initial diagnosis in a local community hospital. Setting Referral centre for interventional treatment of coronary artery disease. Methods During a five year period, 520 candidates for primary coronary angioplasty were treated in our institution, 104 after transfer from a community hospital. The transferred patients and the non-transferred patients (n = 416) were compared with regard to baseline clinical characteristics, time interval from symptom onset to treatment, and clinical outcome at six months. Results In this setting, the influence of transportation on total ischaemic time was limited, and there was no difference in clinical outcome between the transferred and the non-transferred patients. Clinical outcome was mainly dependent on the indication for transfer. Conclusions Safe and expedient transportation may facilitate the more widespread use of primary angioplasty in patients with acute myocardial infarction. A large randomised multicentre trial is needed to compare the relative merits of intravenous thrombolytic treatment in a local hospital with primary angioplasty after transfer in selected high risk patients with acute myocardial infarction.

[1]  H. Suryapranata,et al.  Limitation of Infarct Size and Preservation of Left Ventricular Function After Primary Coronary Angioplast Compared With Intravenous Streptokinase in Acute Myocardial Infarction , 1994, Circulation.

[2]  M. Simoons,et al.  Tailored Thrombolytic Therapy A Perspective , 1993, Circulation.

[3]  J. Reiber,et al.  A comparison of immediate coronary angioplasty with intravenous streptokinase in acute myocardial infarction. , 1993, The New England journal of medicine.

[4]  M. Simoons,et al.  Immediate angioplasty: a conservative view from Europe. , 1995, British heart journal.

[5]  The effects of tissue plasminogen activator, streptokinase, or both on coronary-artery patency, ventricular function, and survival after acute myocardial infarction. , 1993, The New England journal of medicine.

[6]  R. Califf,et al.  Stroke after thrombolysis. Mortality and functional outcomes in the GUSTO-I trial. Global Use of Strategies to Open Occluded Coronary Arteries. , 1995, Circulation.

[7]  J O'Keefe,et al.  A Comparison of Immediate Angioplasty with Thrombolytic Therapy for Acute Myocardial Infarction , 1993 .

[8]  B. Brodie Primary angioplasty in a community hospital in the USA. , 1995, British heart journal.

[9]  R. Boyle Immediate angioplasty in the United Kingdom. , 1995, British heart journal.

[10]  E. Braunwald,et al.  Risk stratification before thrombolytic therapy in patients with acute myocardial infarction. The Thrombolysis in Myocardial Infarction (TIMI) Phase II Co-Investigators. , 1990, Journal of the American College of Cardiology.

[11]  F. Zijlstra Primary angioplasty is the most effective treatment for an acute myocardial infarction. , 1995, British heart journal.

[12]  P. Kligfield Primary angioplasty in myocardial infarction. , 1995, British heart journal.

[13]  F. Balestra,et al.  Epidemiology of avoidable delay in the care of patients with acute myocardial infarction in Italy. A GISSI-generated study. GISSI--Avoidable Delay Study Group. , 1995, Archives of internal medicine.

[14]  J. Reiber,et al.  Angiographic findings and catheterization laboratory events in patients with primary coronary angioplasty or streptokinase therapy for acute myocardial infarction. , 1995, European heart journal.

[15]  B. Brodie,et al.  Outcomes of direct coronary angioplasty for acute myocardial infarction in candidates and non-candidates for thrombolytic therapy. , 1991, The American journal of cardiology.

[16]  J. Gore,et al.  Feasibility and safety of emergency interhospital transport of patients during early hours of acute myocardial infarction. , 1989, Archives of internal medicine.

[17]  R. Califf,et al.  Helicopter transport of patients during acute myocardial infarction. , 1988, The American journal of cardiology.

[18]  P. Ludman Primary angioplasty. , 1998, Hospital medicine.

[19]  D. Ramsdale,et al.  Experience of primary angioplasty in the United Kingdom. , 1995, British heart journal.

[20]  P. Vaitkus Limitations of primary angioplasty in acute myocardial infarction. , 1995, British heart journal.