Micromachined Antenna Stents and Cuffs for Monitoring Intraluminal Pressure and Flow

This paper describes two stainless steel microstructures that are microelectrodischarge machined from 50-mum-thick planar foil for intraluminal measurements of pressure and flow (with potential for applications ranging from blood vessels to bile ducts). The first structure is an inductive antenna stent (stentenna) with 20-mm length and 3.5-mm expanded diameter. It is coupled with capacitive elements to form resonant LC tanks that can be telemetrically queried. The resulting LC tanks are deployed inside silicone mock arteries using standard angioplasty balloons and used in a passive telemetry scheme to sense changes in pressure and flow. Using water as the test fluid, the resonant peaks shift from about 215 to 208 MHz as the flow is increased from 0 to 370 mL/min. The second structure is a ring-shaped intraluminal cuff with two 400times750-mum2 electrodes that are used to provide a direct transduction of flow velocity in the presence of a magnetic field. It is fabricated in a manner similar to the stentenna, but with an insulating segment. The voltage has a linear dependence on flow rate, changing by 3.1-4.3 muV per cm/s of flow (of saline) over a 180 cm/s dynamic range, with a magnetic field of about 0.25 T

[1]  A. Kolin,et al.  An Alternating Field Induction Flow Meter of High Sensitivity , 1945 .

[2]  J. A. Shercliff The theory of electromagnetic flow-measurement , 1962 .

[3]  C J Mills,et al.  A catheter tip electromagnetic velocity probe. , 1966, Physics in medicine and biology.

[4]  An electromagnetic catheter blood flow meter of minimal lateral dimensions. , 1970, Proceedings of the National Academy of Sciences of the United States of America.

[5]  A new approach to electromagnetic blood flow determination by means of catheter in an external magnetic field. , 1970, Proceedings of the National Academy of Sciences of the United States of America.

[6]  A. Kolin,et al.  Approaches to blood-flow measurement by means of electromagnetic catheter flow meters , 1970 .

[7]  Three-electrode probe for catheter-type blood flowmeters. , 1973, IEEE transactions on bio-medical engineering.

[8]  R. H Karol,et al.  Engineering Properties of Soils , 1979 .

[9]  H J Van Peenen,et al.  Abdominal aortic aneurysms: the changing natural history. , 1984, Journal of vascular surgery.

[10]  B. Høivik,et al.  [Abdominal aortic aneurysms]. , 1994, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

[11]  K. Koelling,et al.  Polymeric Surface Modifications of Tantalum Stents , 1996, Journal of endovascular surgery : the official journal of the International Society for Endovascular Surgery.

[12]  E. Edelman,et al.  Pathobiologic responses to stenting. , 1998, The American journal of cardiology.

[13]  John G. Webster,et al.  The Measurement, Instrumentation and Sensors Handbook , 1998 .

[14]  Euisik Yoon,et al.  Hermetically Sealed Inductor-Capacitor (LC) Resonator for Remote Pressure Monitoring , 1998 .

[15]  Fabrication of a Micro Electromagnetic Flow Sensor for Micro Flow Rate Measurement , 2000 .

[16]  The durability of silicone versus latex mock arteries. , 2001, Biomedical sciences instrumentation.

[17]  K. Najafi,et al.  A wireless batch sealed absolute capacitive pressure sensor , 2001 .

[18]  The durability of silicone versus latex mock arteries. , 2001 .

[19]  M. Fonseca,et al.  Wireless micromachined ceramic pressure sensor for high-temperature applications , 2002 .

[20]  Y. Gianchandani,et al.  Batch mode micro-electro-discharge machining , 2002 .

[21]  K. Wise,et al.  A double-sided single-chip wireless pressure sensor , 2002, Technical Digest. MEMS 2002 IEEE International Conference. Fifteenth IEEE International Conference on Micro Electro Mechanical Systems (Cat. No.02CH37266).

[22]  K.D. Wise,et al.  An all-capacitive sensing chip for temperature, absolute pressure, and relative humidity , 2003, TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664).

[23]  K. Takahata,et al.  Stentenna: a micromachined antenna stent for wireless monitoring of implantable microsensors , 2003, Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439).

[24]  Endovascular therapy for aortic disease. , 2004, Surgical technology international.

[25]  K. Wise,et al.  A wireless microsensor for monitoring flow and pressure in a blood vessel utilizing a dual-inductor antenna stent and two pressure sensors , 2004, 17th IEEE International Conference on Micro Electro Mechanical Systems. Maastricht MEMS 2004 Technical Digest.

[26]  Yukihito Saito,et al.  Airway Stenting , 2004, Surgery Today.

[28]  K. Takahata,et al.  A planar approach for manufacturing cardiac stents: design, fabrication, and mechanical evaluation , 2004, Journal of Microelectromechanical Systems.

[29]  R. Dayal,et al.  Stent graft treatment for abdominal aortic aneurysm repair: recent developments in therapy , 2004, Current opinion in cardiology.

[30]  R. Chapman,et al.  Review article: current management of primary sclerosing cholangitis , 2005, Alimentary pharmacology & therapeutics.

[31]  Carotid artery stenting for the high surgical risk patients. , 2005, The Journal of cardiovascular surgery.

[32]  Suncica Canic,et al.  Mathematical Model analysis of Wallstent and Aneurx: dynamic responses of bare-metal endoprosthesis compared with those of stent-graft. , 2005, Texas Heart Institute journal.

[33]  Y. Gianchandani,et al.  Micromachined intraluminal devices for active and passive electromagnetic measurements of flow , 2005, 18th IEEE International Conference on Micro Electro Mechanical Systems, 2005. MEMS 2005..

[34]  K. Takahata,et al.  A micromachined Kelvin probe with integrated actuator for microfluidic and solid-state applications , 2005, Journal of Microelectromechanical Systems.

[35]  R. Carrau Use of stents in head and neck surgery , 2005, Current opinion in otolaryngology & head and neck surgery.

[36]  Guang-Zhong Yang,et al.  Blood Flow Measurement , 2006 .

[37]  D. G. Wyatt,et al.  An improved perivascular electromagnetic flowmeter , 2006, Medical and biological engineering.

[38]  K.D. Wise,et al.  A fully integrated multisite pressure sensor for wireless arterial flow characterization , 2006, Journal of Microelectromechanical Systems.