Detailed modeling and numerical analysis of photoreceptor cells exposed to electromagnetic fields

This paper presents the fine modeling and simulation of retinal rod cells under exposure to electromagnetic waves at power, Radio and microwave frequencies. The novelty lies in detailed modeling according to recent electron micrographs of the actual geometry of retinal cell. Local heat generation at different sites in the cell is shown for different frequencies.

[1]  A. J. Ladman The Fine Structure of the Rod-Bipolar Cell Synapse in the Retina of the Albino Rat , 1958, The Journal of biophysical and biochemical cytology.

[2]  R. Sorrentino,et al.  Computation of electromagnetic field inside a tissue at mobile communications frequencies , 2003 .

[3]  Wenjun Ying,et al.  Hybrid Finite Element Method for Describing the Electrical Response of Biological Cells to Applied Fields , 2007, IEEE Transactions on Biomedical Engineering.

[4]  H. Lodish Molecular Cell Biology , 1986 .

[5]  H P Schwan,et al.  Cellular membrane potentials induced by alternating fields. , 1992, Biophysical journal.

[6]  Investigating the effects of external fields polarization on the coupling of pure magnetic waves in the human body in very low frequencies , 2007, Biomagnetic research and technology.

[7]  C. R. Braekevelt Fine structure of the retinal photoreceptors of the emu (Dromaius novaehollandiae). , 1998, Tissue & cell.

[8]  M.A. Stuchly,et al.  Modeling assemblies of biological cells exposed to electric fields , 1997, IEEE Transactions on Biomedical Engineering.

[9]  Ravindra P. Joshi,et al.  Modeling studies of cellular response to ultrashort, high-intensity electric fields , 2003, 2003 Annual Report Conference on Electrical Insulation and Dielectric Phenomena.

[10]  S. Abdallah,et al.  Finite-Difference Time-Domain Simulations of Light Scattering from Retinal Photoreceptors , 2007 .

[11]  E. Muto,et al.  Dielectric measurement of individual microtubules using the electroorientation method. , 2006, Biophysical journal.

[12]  Helmut Grubmüller,et al.  Kinetics, statistics, and energetics of lipid membrane electroporation studied by molecular dynamics simulations. , 2008, Biophysical journal.

[13]  James C Weaver,et al.  An approach to electrical modeling of single and multiple cells , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[14]  Jan Gimsa,et al.  The influence of the molecular structure of lipid membranes on the electric field distribution and energy absorption , 2006, Bioelectromagnetics.

[15]  Herman P. Schwan,et al.  Biological effects of non-ionizing radiations: Cellular properties and interactions , 1986, Annals of Biomedical Engineering.

[16]  A. H. Bunt Fine structure and radioautography of rabbit photoreceptor cells. , 1978, Investigative ophthalmology & visual science.

[17]  S. Ridella,et al.  Evaluation of electrical fields inside a biological structure. , 1982, The British journal of cancer. Supplement.