NSAIDs inhibit bone healing through the downregulation of TGF-β3 expression during endochondral ossification.
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[1] T. Salo,et al. The Role of MMP8 in Cancer: A Systematic Review , 2019, International journal of molecular sciences.
[2] Sakae Tanaka,et al. Effect of the small compound TD‐198946 on glycosaminoglycan synthesis and transforming growth factor β3‐associated chondrogenesis of human synovium‐derived stem cells in vitro , 2019, Journal of tissue engineering and regenerative medicine.
[3] A. Tamas,et al. Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) Reduces Oxidative and Mechanical Stress-Evoked Matrix Degradation in Chondrifying Cell Cultures , 2019, International journal of molecular sciences.
[4] J. Post,et al. Co-treatment of TGF-β3 and BMP7 is superior in stimulating chondrocyte redifferentiation in both hypoxia and normoxia compared to single treatments , 2018, Scientific Reports.
[5] G. Vunjak‐Novakovic,et al. Testing the potency of anti‐TNF‐α and anti‐IL‐1β drugs using spheroid cultures of human osteoarthritic chondrocytes and donor‐matched chondrogenically differentiated mesenchymal stem cells , 2018, Biotechnology progress.
[6] Hae-Ryong Song,et al. In Vitro Anti-Inflammation and Chondrogenic Differentiation Effects of Inclusion Nanocomplexes of Hyaluronic Acid-Beta Cyclodextrin and Simvastatin , 2018, Tissue Engineering and Regenerative Medicine.
[7] Sigrid A. Langhans. Three-Dimensional in Vitro Cell Culture Models in Drug Discovery and Drug Repositioning , 2018, Front. Pharmacol..
[8] F. Sefat,et al. Effect of transforming growth factor-β3 on mono and multilayer chondrocytes. , 2016, Cytokine.
[9] A. Blejec,et al. Gene expression of cultured human chondrocytes as a model for assessing neutralization efficacy of soluble TNFα by TNFα antagonists. , 2015, Biologicals : journal of the International Association of Biological Standardization.
[10] G. Stein,et al. Runx1 Activities in Superficial Zone Chondrocytes, Osteoarthritic Chondrocyte Clones and Response to Mechanical Loading , 2015, Journal of cellular physiology.
[11] T. Brosh,et al. Statins Enhance Rotator Cuff Healing by Stimulating the COX2/PGE2/EP4 Pathway , 2014, The American journal of sports medicine.
[12] Timothy P. Kurmis,et al. The effect of nonsteroidal anti-inflammatory drug administration on acute phase fracture-healing: a review. , 2012, The Journal of bone and joint surgery. American volume.
[13] P. Giannoudis,et al. Do Nonsteroidal Anti-Inflammatory Drugs Affect Bone Healing? A Critical Analysis , 2012, TheScientificWorldJournal.
[14] P. Giannoudis,et al. The effect of antibiotics on bone healing: current evidence , 2011, Expert opinion on drug safety.
[15] Thomas A Einhorn,et al. The biology of fracture healing. , 2011, Injury.
[16] P. Giannoudis,et al. Nonsteroidal anti-inflammatory drugs: prostaglandins, indications, and side effects , 2011 .
[17] P. Giannoudis,et al. NSAIDS inhibit in vitro MSC chondrogenesis but not osteogenesis: implications for mechanism of bone formation inhibition in man , 2010, Journal of cellular and molecular medicine.
[18] Gwo‐Jaw Wang,et al. Anti-inflammatory drugs suppress proliferation and induce apoptosis through altering expressions of cell cycle regulators and pro-apoptotic factors in cultured human osteoblasts. , 2009, Toxicology.
[19] S. Abramson,et al. Prostaglandin E2 Exerts Catabolic Effects in Osteoarthritis Cartilage: Evidence for Signaling via the EP4 Receptor1 , 2008, The Journal of Immunology.
[20] P. Giannoudis,et al. Pharmacological agents and impairment of fracture healing: what is the evidence? , 2008, Injury.
[21] Gwo‐Jaw Wang,et al. Effects of anti-inflammatory drugs on proliferation, cytotoxicity and osteogenesis in bone marrow mesenchymal stem cells. , 2007, Biochemical pharmacology.
[22] A. M. Simon,et al. Dose and time-dependent effects of cyclooxygenase-2 inhibition on fracture-healing. , 2007, The Journal of bone and joint surgery. American volume.
[23] Meijing Wang,et al. HIGH PASSAGE NUMBER OF STEM CELLS ADVERSELY AFFECTS STEM CELL ACTIVATION AND MYOCARDIAL PROTECTION , 2006, Shock.
[24] E Jones,et al. Growing bone and cartilage. The role of mesenchymal stem cells. , 2006, The Journal of bone and joint surgery. British volume.
[25] P. Giannoudis,et al. Biology of mesenchymal stem cells. , 2005, Injury.
[26] J. Bijlsma,et al. Selective COX-2 inhibition is favorable to human early and late-stage osteoarthritic cartilage: a human in vitro study. , 2005, Osteoarthritis and cartilage.
[27] I. Martin,et al. Chondrogenesis of expanded adult human articular chondrocytes is enhanced by specific prostaglandins. , 2004, Rheumatology.
[28] J. Bijlsma,et al. Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage. , 2002, Rheumatology.
[29] R Cancedda,et al. Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model. , 2000, Journal of cell science.
[30] M. Ho,et al. Effects of nonsteroidal anti-inflammatory drugs and prostaglandins on osteoblastic functions. , 1999, Biochemical pharmacology.
[31] O. Ljunggren,et al. Inflammatory cytokines regulate proliferation of cultured human osteoblasts. , 1997, Acta orthopaedica Scandinavica.
[32] K Banovac,et al. Effect of Nonsteroidal Antiinflammatory Drugs on Fracture Healing: A Laboratory Study in Rats , 1995, Journal of orthopaedic trauma.
[33] M. Centrella,et al. Differential actions of prostaglandins in separate cell populations from fetal rat bone. , 1994, Endocrinology.
[34] R. Pelker,et al. The influence of ibuprofen on fracture repair: Biomechanical, biochemical, histologic, and histomorphometric parameters in rats , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[35] S. Muallem,et al. Modulation of osteoblast function by prostaglandins. , 1989, The American journal of physiology.
[36] Louis C. Gerstenfeld,et al. Fracture healing: mechanisms and interventions , 2015, Nature Reviews Rheumatology.
[37] M. Malaise,et al. Effects of meloxicam compared to acetylsalicylic acid in human articular chondrocytes. , 1997, Pharmacology.
[38] R. Pigott,et al. ICAM-1 expression on chondrocytes in rheumatoid arthritis: induction by synovial cytokines , 1992, Mediators of inflammation.