Management of small polyps detected by screening CT colonography: patient and physician preferences.

BACKGROUND Management of small polyps found on computed tomography (CT) colonography is controversial and critical to both cancer outcomes and cost. Patient and physician behavior are influenced by personal beliefs and prior experience. Thus, we aimed to understand patient and physician preferences after finding polyps on CT colonography. METHODS Patients were given a validated handout and survey asking for their preference for evaluation of a "pea-sized" polyp found on CT colonography. By using an Internet survey, physicians were asked how they would manage a 5-mm, 8-mm, or 12-mm polyp, or three 5-mm polyps found by CT colonography in a hypothetical 52-year-old patient of average colorectal cancer risk. Survey reliability was assessed using Cronbach's coefficient alpha. RESULTS Of the 305 patient respondents, 95% wanted to know if the polyp found on CT colonography was precancerous, 86% stated they would request endoscopic evaluation, and 85% wanted polypectomy. Of the 277 primary care physicians, 71% would refer a 5-mm sigmoid polyp for endoscopy, 86% would refer an 8-mm polyp, 97% would refer a 12-mm polyp, and 91% would refer three 5-mm polyps. Of the 461 gastroenterologists, 83% would refer a 5-mm sigmoid polyp for endoscopy, 96% would refer an 8-mm polyp, 97% would refer a 12-mm polyp, and 93% would refer three 5-mm polyps. Overall, 75% of physicians indicated the fear of missing a precancerous lesion would prompt referral for colonoscopy. CONCLUSION Both patients and physicians overwhelmingly preferred to follow up small polyps identified by CT colonography with endoscopy, suggesting that population-based CT colonography screening programs in which polyps are not removed might require significant patient and physician education before implementation.

[1]  G Scott Gazelle,et al.  The management of small polyps found by virtual colonoscopy: results of a decision analysis. , 2007, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[2]  D. Lieberman,et al.  ACG Colorectal Cancer Prevention Action Plan: Update On CT-Colonography , 2006, The American Journal of Gastroenterology.

[3]  A. Zauber,et al.  The National Polyp Study. Patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. , 1990, Gastroenterology.

[4]  T. Read,et al.  Importance of adenomas 5 mm or less in diameter that are detected by sigmoidoscopy. , 1997, The New England journal of medicine.

[5]  Perry J Pickhardt,et al.  Screening for colorectal neoplasia with CT colonography: initial experience from the 1st year of coverage by third-party payers. , 2006, Radiology.

[6]  H Shinya,et al.  Morphology, anatomic distribution and cancer potential of colonic polyps. , 1979, Annals of surgery.

[7]  David H. Kim,et al.  CT colonography versus colonoscopy for the detection of advanced neoplasia. , 2007, The New England journal of medicine.

[8]  S. Park,et al.  Flat colorectal neoplasms: definition, importance, and visualization on CT colonography. , 2007, AJR. American journal of roentgenology.

[9]  A. Zauber,et al.  Initial management and follow-up surveillance of patients with colorectal adenomas. , 1997, Gastroenterology clinics of North America.

[10]  A. Zauber,et al.  Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup. , 1993 .

[11]  Michael D. Kaplowitz,et al.  A Comparison of Web and Mail Survey Response Rates , 2004 .

[12]  J. Burdick,et al.  Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasia. , 2004, JAMA.

[13]  P. Maisonneuve,et al.  Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps. , 2008, Gastroenterology.

[14]  Morson Bc Evolution of cancer of the colon and rectum. , 1974 .

[15]  Angelo Zullo,et al.  Cost‐effectiveness of colorectal cancer screening with computed tomography colonography , 2007, Cancer.

[16]  J. Yee,et al.  CT colonography reporting and data system: a consensus proposal. , 2005, Radiology.

[17]  Perry J Pickhardt,et al.  Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline from the American Cancer Society, the US Multi‐Society Task Force on Colorectal Cancer, and the American College of Radiology * † , 2008, CA: a cancer journal for clinicians.

[18]  E. Paulson,et al.  Analysis of air contrast barium enema, computed tomographic colonography, and colonoscopy: prospective comparison , 2005, The Lancet.

[19]  M Koutantji,et al.  How willing are patients to question healthcare staff on issues related to the quality and safety of their healthcare? An exploratory study , 2008, Quality & Safety in Health Care.

[20]  A. Zauber,et al.  The National Polyp Study , 1990 .

[21]  B. Levin,et al.  Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. , 2008, Gastroenterology.

[22]  A. Sonnenberg,et al.  Prevention of Colorectal Cancer by Flexible Endoscopy and Polypectomy: A Case-Control Study of 32 702 Veterans , 1995, Annals of Internal Medicine.

[23]  P. Pickhardt,et al.  Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. , 2003, The New England journal of medicine.

[24]  G. Ros,et al.  Changes in some constituents of pea seed during commercial canning , 1993, Plant foods for human nutrition.

[25]  Daniel S. Miller,et al.  The annual report to the nation on the status of cancer, 1973–1997, with a special section on colorectal cancer , 2000, Cancer.

[26]  Robert H Fletcher,et al.  Guidelines for Colonoscopy Surveillance after Polypectomy: A Consensus Update by the US Multi‐Society Task Force on Colorectal Cancer and the American Cancer Society * , † , 2006, Gastroenterology.

[27]  C. Green,et al.  Gender, psychosocial factors and the use of medical services: a longitudinal analysis. , 1999, Social science & medicine.

[28]  J. Bond,et al.  Clinical evidence for the adenoma-carcinoma sequence, and the management of patients with colorectal adenomas. , 2000, Seminars in gastrointestinal disease.

[29]  H. Pohl,et al.  Prevalence of clinically important histology in small adenomas. , 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[30]  Perry J Pickhardt,et al.  Small and diminutive polyps detected at screening CT colonography: a decision analysis for referral to colonoscopy. , 2008, AJR. American journal of roentgenology.

[31]  Endoscopic polypectomy reduces mortality from colorectal cancer. , 1995, Archives of internal medicine.

[32]  Hans Feichtinger,et al.  High-grade dysplasia and invasive carcinoma in colorectal adenomas: a multivariate analysis of the impact of adenoma and patient characteristics , 2002, European journal of gastroenterology & hepatology.

[33]  Stephan D. Fihn,et al.  How Doctors and Patients Discuss Routine Clinical Decisions: Informed Decision Making in the Outpatient Setting , 1997 .

[34]  S. Park,et al.  False-negative results at multi-detector row CT colonography: multivariate analysis of causes for missed lesions. , 2005, Radiology.