Diaflux: A Graphical Language for Computer-Interpretable Guidelines

In this paper, we introduce the formal representation language DiaFlux, that is simple and easy to use on the one hand. On the other hand it allows for the definition of Computer-Interpretable Guidelines (CIGs), that can solve valuable tasks being executed in the clinical context. Further, we describe a wiki-driven development process using the stepwise formalization and allowing for almost self-acquisition by the domain specialists. The applicability of the approach is demonstrated by a protocol for sepsis monitoring and treatment developed by a collaboration of clinicians.

[1]  Katharina Kaiser,et al.  Computer-interpretable Guideline Formalisms , 2008, Computer-based Medical Guidelines and Protocols.

[2]  Florian Lemmerich,et al.  An Extensible Semantic Wiki Architecture , 2009, SemWiki.

[3]  Antonio Moreno,et al.  Computer-based execution of clinical guidelines: A review , 2008, Int. J. Medical Informatics.

[4]  Peter J. F. Lucas,et al.  A constraint-based approach to medical guidelines and protocols. , 2006 .

[5]  Omolola Ogunyemi,et al.  GLIF3: a representation format for sharable computer-interpretable clinical practice guidelines , 2004, J. Biomed. Informatics.

[6]  Lora Aroyo,et al.  The Semantic Web: Research and Applications , 2009, Lecture Notes in Computer Science.

[7]  John Fox,et al.  Comparing computer-interpretable guideline models: a case-study approach. , 2003, Journal of the American Medical Informatics Association : JAMIA.

[8]  Stefanie N. Lindstaedt,et al.  MoKi: The Enterprise Modelling Wiki , 2009, ESWC.

[9]  Dean Allemang,et al.  The Semantic Web - ISWC 2006, 5th International Semantic Web Conference, ISWC 2006, Athens, GA, USA, November 5-9, 2006, Proceedings , 2006, SEMWEB.

[10]  Michel Dojat,et al.  SmartCareTM-Automated Clinical Guidelines in Critical Care , 2004, ECAI.

[11]  Yuval Shahar,et al.  ASBRU: A TASK-SPECIFIC, INTENTION-BASED, AND TIME-ORIENTED LANGUAGE FOR REPRESENTING SKELETAL PLANS , 1999 .

[12]  Frank Puppe,et al.  Engineering intelligent systems on the knowledge formalization continuum , 2011, Int. J. Appl. Math. Comput. Sci..

[13]  John Fox,et al.  Disseminating medical knowledge: the PROforma approach , 1998, Artif. Intell. Medicine.

[14]  Frank Puppe,et al.  Preprint: The final publication is available at springerlink.com KnowWE: A Semantic Wiki for Knowledge Engineering , 2022 .

[15]  Kenneth D. Forbus,et al.  Building Problem Solvers , 1993 .

[16]  Markus Krötzsch,et al.  Semantic MediaWiki , 2006, International Semantic Web Conference.

[17]  Sebastian Schaffert,et al.  IkeWiki: A Semantic Wiki for Collaborative Knowledge Management , 2006, 15th IEEE International Workshops on Enabling Technologies: Infrastructure for Collaborative Enterprises (WETICE'06).

[18]  François Bry,et al.  Semantic Wikis , 2008, IEEE Software.

[19]  Peter J. F. Lucas Computer-based Medical Guidelines and Protocols: A Primer and Current Trends , 2008 .

[20]  Silvia Miksch,et al.  Modeling Clinical Protocols Using Semantic MediaWiki: The Case of the Oncocure Project , 2008, K4HelP.