Radiofrequency thermal ablation of liver tumors

Chemotherapy and radiation therapy are ineffective against primary and secondary malignant hepatic tumors. Surgical resection has been considered the only potentially curative option, but few patients with hepatic tumors are candidates for surgery. Recent results suggest that radiofrequency thermal ablation may be an effective, minimally invasive technique for treating malignant hepatic tumors. Sonography is the primary technique for guiding percutaneous ablative procedures. We review the current research and clinical experience with radiofrequency thermal ablation for treating malignant hepatic tumors. © 1999 John Wiley & Sons, Inc. J Clin Ultrasound 27:221–229, 1999.

[1]  F. Garbagnati,et al.  Percutaneous treatment of small hepatic tumors by an expandable RF needle electrode. , 1998, AJR. American journal of roentgenology.

[2]  E. Patterson,et al.  Radiofrequency ablation of porcine liver in vivo: effects of blood flow and treatment time on lesion size. , 1998, Annals of surgery.

[3]  L Solbiati,et al.  Ablation of liver tumors using percutaneous RF therapy. , 1998, AJR. American journal of roentgenology.

[4]  J. Lewin,et al.  Invited. Interactive MRI‐guided radiofrequency interstitial thermal ablation of abdominal tumors: Clinical trial for evaluation of safety and feasibility , 1998, Journal of magnetic resonance imaging : JMRI.

[5]  J. Lewin,et al.  MR monitoring of MR‐guided radiofrequency thermal ablation of normal liver in an animal model , 1998, Journal of magnetic resonance imaging : JMRI.

[6]  L Solbiati,et al.  Hepatic metastases: percutaneous radio-frequency ablation with cooled-tip electrodes. , 1997, Radiology.

[7]  Percutaneous microwave coagulation therapy in liver tumors , 1997, Acta radiologica.

[8]  L Solbiati,et al.  Saline-enhanced radio-frequency tissue ablation in the treatment of liver metastases. , 1997, Radiology.

[9]  R Fiocca,et al.  Percutaneous US-guided radio-frequency tissue ablation of liver metastases: treatment and follow-up in 16 patients. , 1997, Radiology.

[10]  R C Nelson,et al.  Sonography: the undiscovered jewel of interventional radiology. , 1996, Radiographics : a review publication of the Radiological Society of North America, Inc.

[11]  F. Garbagnati,et al.  Percutaneous RF interstitial thermal ablation in the treatment of hepatic cancer. , 1996, AJR. American journal of roentgenology.

[12]  G. Gazelle,et al.  Radiofrequency tissue ablation: increased lesion diameter with a perfusion electrode. , 1996, Academic radiology.

[13]  T. Lorentzen,et al.  A cooled needle electrode for radiofrequency tissue ablation: thermodynamic aspects of improved performance compared with conventional needle design. , 1996, Academic radiology.

[14]  J. McGahan,et al.  Hepatic ablation using bipolar radiofrequency electrocautery. , 1996, Academic radiology.

[15]  D I Rosenthal,et al.  Radiofrequency tissue ablation: importance of local temperature along the electrode tip exposure in determining lesion shape and size. , 1996, Academic radiology.

[16]  T. Lorentzen The loop electrode: in vitro evaluation of a device for ultrasound-guided interstitial tissue ablation using radiofrequency electrosurgery. , 1996, Academic radiology.

[17]  T. Livraghi,et al.  Hepatocellular carcinoma and cirrhosis in 746 patients: long-term results of percutaneous ethanol injection. , 1995, Radiology.

[18]  G S Gazelle,et al.  Radiofrequency tissue ablation in the rabbit lung: efficacy and complications. , 1995, Academic radiology.

[19]  S L Dawson,et al.  Tissue ablation with radiofrequency using multiprobe arrays. , 1995, Academic radiology.

[20]  M. L. Weaver,et al.  Hepatic cryosurgery in treating colorectal metastases , 1995, Cancer.

[21]  M Deimling,et al.  Malignant liver tumors treated with MR imaging-guided laser-induced thermotherapy: technique and prospective results. , 1995, Radiology.

[22]  S L Dawson,et al.  Tissue ablation with radiofrequency: effect of probe size, gauge, duration, and temperature on lesion volume. , 1995, Academic radiology.

[23]  H. D’Agostino,et al.  Percutaneous ablation therapy for hepatocellular carcinomas. , 1995, AJR. American journal of roentgenology.

[24]  T. Starzl,et al.  Experience in hepatic resection for metastatic colorectal cancer: analysis of clinical and pathologic risk factors. , 1994, Surgery.

[25]  Toshihito Seki,et al.  Ultrasonically guided percutaneous microwave coagulation therapy for small hepatocellular carcinoma , 1994, Cancer.

[26]  R. Busuttil,et al.  Current Treatment Modalities for Hepatocellular Carcinoma , 1994, Annals of surgery.

[27]  W R Lees,et al.  Hepatic metastases: interstitial laser photocoagulation with real-time US monitoring and dynamic CT evaluation of treatment. , 1993, Radiology.

[28]  N. Petrelli,et al.  Morbidity and survival of liver resection for colorectal adenocarcinoma , 1991, Diseases of the colon and rectum.

[29]  R. Lazzara,et al.  Catheter ablation of accessory atrioventricular pathways (Wolff-Parkinson-White syndrome) by radiofrequency current. , 1991, The New England journal of medicine.

[30]  J. McGahan,et al.  Hepatic ablation using radiofrequency electrocautery. , 1990, Investigative radiology.

[31]  L. Buscarini,et al.  Thermal Lesions Induced by 480 KHz Localized Current Field in Guinea Pig and Pig Liver , 1990, Tumori.

[32]  T. Ravikumar,et al.  Resection of hepatic metastases from colorectal cancer. Biologic perspective. , 1989, Annals of surgery.

[33]  E. Cosman,et al.  Stereotactic radiofrequency lesion making. , 1983, Applied neurophysiology.

[34]  L. Organ Electrophysiologic principles of radiofrequency lesion making. , 1976, Applied neurophysiology.