Inhibition of platelet-derived growth factor (PDGF) receptor affects follicular development and ovarian proliferation, apoptosis and angiogenesis in prepubertal eCG-treated rats.

[1]  K. McNatty,et al.  Control of early ovarian follicular development. , 2019, Journal of reproduction and fertility. Supplement.

[2]  M. Sirard,et al.  Global gene expression in granulosa cells of growing, plateau and atretic dominant follicles in cattle , 2015, Reproductive Biology and Endocrinology.

[3]  A. Bukovsky.  Novel methods of treating ovarian infertility in older and POF women, testicular infertility, and other human functional diseases , 2015, Reproductive Biology and Endocrinology.

[4]  E. Hwang,et al.  Platelet-derived Growth Factor-C (PDGF-C) Induces Anti-apoptotic Effects on Macrophages through Akt and Bad Phosphorylation* , 2014, The Journal of Biological Chemistry.

[5]  J. Luan,et al.  Platelet-derived growth factor receptor kinase inhibitor AG-1295 promotes osteoblast differentiation in MC3T3-E1 cells via the Erk pathway. , 2012, Bioscience trends.

[6]  T. Kitazono,et al.  PDGF receptor β signaling in pericytes following ischemic brain injury. , 2012, Current neurovascular research.

[7]  Zhi-Ren Liu,et al.  PDGF Upregulates Mcl-1 Through Activation of β-Catenin and HIF-1α-Dependent Signaling in Human Prostate Cancer Cells , 2012, PloS one.

[8]  M. Tesone,et al.  Angiopoietin 1 reduces rat follicular atresia mediated by apoptosis through the PI3K/Akt pathway , 2011, Molecular and Cellular Endocrinology.

[9]  A. Mcneilly,et al.  Theca: the forgotten cell of the ovarian follicle. , 2010, Reproduction.

[10]  M. Tesone,et al.  Direct survival role of vascular endothelial growth factor (VEGF) on rat ovarian follicular cells , 2010, Molecular and Cellular Endocrinology.

[11]  D. Choi,et al.  The role of autophagy in follicular development and atresia in rat granulosa cells. , 2010, Fertility and sterility.

[12]  Kathryn J. Woad,et al.  Angiogenesis and vascular function in the ovary. , 2009, Reproduction.

[13]  Sheng-Hsiang Li,et al.  Luteinizing hormone increases platelet-derived growth factor-D gene expression in human granulosa-luteal cells. , 2009, Fertility and sterility.

[14]  G. Gores,et al.  Life and death by death receptors , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[15]  D. Andrews,et al.  Bid: a Bax-like BH3 protein , 2008, Oncogene.

[16]  C. Kuo,et al.  Soluble receptor-mediated selective inhibition of VEGFR and PDGFRβ signaling during physiologic and tumor angiogenesis , 2008, Proceedings of the National Academy of Sciences.

[17]  B. Fisch,et al.  Platelet-derived growth factors (PDGF-A and -B) and their receptors in human fetal and adult ovaries. , 2008, Molecular human reproduction.

[18]  M. Tesone,et al.  Intrabursal Administration of the Antiangiopoietin 1 Antibody Produces a Delay in Rat Follicular Development Associated with an Increase in Ovarian Apoptosis Mediated by Changes in the Expression of BCL2 Related Genes1 , 2008, Biology of reproduction.

[19]  R. Soares,et al.  Anti-angiogenic effects of imatinib target smooth muscle cells but not endothelial cells , 2007, Angiogenesis.

[20]  M. Tesone,et al.  Inhibition of cytochrome P-450 C17 enzyme by a GnRH agonist in ovarian follicles from gonadotropin-stimulated rats. , 2007, American journal of physiology. Endocrinology and metabolism.

[21]  L. S. Sleer,et al.  Platelet-Derived Growth Factors and Receptors in the Rat Corpus Luteum: Localization and Identification of an Effect on Luteogenesis1 , 2007, Biology of reproduction.

[22]  L. S. Sleer,et al.  Cell-Type Localization of Platelet-Derived Growth Factors and Receptors in the Postnatal Rat Ovary and Follicle1 , 2007, Biology of reproduction.

[23]  M. Tesone,et al.  Effect of a Vascular Endothelial Growth Factor (VEGF) Inhibitory Treatment on the Folliculogenesis and Ovarian Apoptosis in Gonadotropin-Treated Prepubertal Rats1 , 2006, Biology of reproduction.

[24]  C. Betsholtz,et al.  Endothelial/Pericyte Interactions , 2005, Circulation research.

[25]  D. Schams,et al.  Role of vascular endothelial growth factor in ovarian physiology - an overview. , 2005, Reproductive biology.

[26]  Mahmoud R Hussein,et al.  Apoptosis in the ovary: molecular mechanisms. , 2005, Human reproduction update.

[27]  M. Tesone,et al.  Gonadotropin-Releasing Hormone Antagonist Antide Inhibits Apoptosis of Preovulatory Follicle Cells in Rat Ovary1 , 2005, Biology of reproduction.

[28]  H. Fraser,et al.  Effects of GnRH antagonist treatment on follicular development and angiogenesis in the primate ovary. , 2004, The Journal of endocrinology.

[29]  C Tamanini,et al.  Angiogenesis in developing follicle and corpus luteum. , 2004, Reproduction in domestic animals = Zuchthygiene.

[30]  R. Webb,et al.  Endocrine and paracrine control of follicular development and ovulation rate in farm species. , 2004, Animal reproduction science.

[31]  H. Fraser,et al.  Angiogenesis in the corpus luteum , 2003, Reproductive biology and endocrinology : RB&E.

[32]  D. Stocco,et al.  Steroidogenic Acute Regulatory Protein in Ovarian Follicles of Gonadotropin-Stimulated Rats Is Regulated by a Gonadotropin-Releasing Hormone Agonist1 , 2003, Biology of reproduction.

[33]  C. Friedman,et al.  Vascular Endothelial Growth Factor Stimulates Preantral Follicle Growth in the Rat Ovary1 , 2003, Biology of reproduction.

[34]  M. Tesone,et al.  Effects of a Gonadotropin-Releasing Hormone Agonist on Rat Ovarian Follicle Apoptosis: Regulation by Epidermal Growth Factor and the Expression of Bcl-2-Related Genes1 , 2002, Biology of reproduction.

[35]  M. Tesone,et al.  Gonadotropin‐releasing hormone agonist affects rat ovarian follicle development by interfering with FSH and growth factors on the prevention of apoptosis , 2001, Molecular reproduction and development.

[36]  A. Jablonka-Shariff,et al.  Evidence for a Role of Capillary Pericytes in Vascular Growth of the Developing Ovine Corpus Luteum1 , 2001, Biology of reproduction.

[37]  S. Wiegand,et al.  Angiogenesis During Follicular Development in the Primate and its Inhibition by Treatment with Truncated Flt-1-Fc (Vascular Endothelial Growth Factor TrapA40). , 2001, Endocrinology.

[38]  J. Rothberg,et al.  PDGF-D, a new protease-activated growth factor , 2001, Nature Cell Biology.

[39]  Holger Gerhardt,et al.  Lack of Pericytes Leads to Endothelial Hyperplasia and Abnormal Vascular Morphogenesis , 2001, The Journal of cell biology.

[40]  A. Moon,et al.  Both Platelet-Derived Growth Factor Receptor (PDGFR)-α and PDGFR-β Promote Murine Fibroblast Cell Migration , 2001 .

[41]  M. Bacci,et al.  Vascular Endothelial Growth Factor Production in Growing Pig Antral Follicles1 , 2000, Biology of reproduction.

[42]  C. Heldin,et al.  PDGF-C is a new protease-activated ligand for the PDGF α-receptor , 2000, Nature Cell Biology.

[43]  Christopher C. Taylor,et al.  Platelet-Derived Growth Factor Activates Porcine Thecal Cell Phosphatidylinositol-3-Kinase-Akt/PKB and Ras-Extracellular Signal-Regulated Kinase-1/2 Kinase Signaling Pathways via the Platelet-Derived Growth Factor-β Receptor. , 2000, Endocrinology.

[44]  A. Hsueh,et al.  Tissue-specific Bcl-2 protein partners in apoptosis: An ovarian paradigm. , 2000, Physiological reviews.

[45]  S. R. Datta,et al.  Cellular survival: a play in three Akts. , 1999, Genes & development.

[46]  C. Betsholtz,et al.  Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. , 1999, Development.

[47]  S. Chun,et al.  Keratinocyte growth factor promotes the survival, growth, and differentiation of preantral ovarian follicles. , 1999, Fertility and sterility.

[48]  A. Arıcı,et al.  Proliferation and differentiation of rat theca-interstitial cells: comparison of effects induced by platelet-derived growth factor and insulin-like growth factor-I. , 1999, Biology of reproduction.

[49]  C. Heldin,et al.  Mechanism of action and in vivo role of platelet-derived growth factor. , 1999, Physiological reviews.

[50]  S. Vanzulli,et al.  Regulation of follicular luteinization by a gonadotropin‐releasing hormone agonist: Relationship between steroidogenesis and apoptosis , 1998, Molecular reproduction and development.

[51]  V. Dixit,et al.  Death receptors: signaling and modulation. , 1998, Science.

[52]  C. Heldin,et al.  Signal transduction via platelet-derived growth factor receptors. , 1998, Biochimica et biophysica acta.

[53]  B. Tsang,et al.  Caspase-3 in the rat ovary: localization and possible role in follicular atresia and luteal regression. , 1998, Biology of reproduction.

[54]  I. Fishbein,et al.  PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swine. , 1998, Circulation.

[55]  Takashi Suzuki,et al.  Cyclic changes of vasculature and vascular phenotypes in normal human ovaries. , 1998, Human reproduction.

[56]  B R Johansson,et al.  Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. , 1997, Science.

[57]  D. Redmer,et al.  Angiogenesis in the ovary. , 1996, Reviews of reproduction.

[58]  T. Maruo,et al.  Immunological evidence for the expression of the Fas antigen in the infant and adult human ovary during follicular regression and atresia. , 1996, The Journal of clinical endocrinology and metabolism.

[59]  S. Chun,et al.  Hormonal regulation of apoptosis in early antral follicles: follicle-stimulating hormone as a major survival factor. , 1996, Endocrinology.

[60]  L. Claesson-Welsh.  Mechanism of action of platelet-derived growth factor. , 1996, The international journal of biochemistry & cell biology.

[61]  C A Smith,et al.  Identification and characterization of a new member of the TNF family that induces apoptosis. , 1995, Immunity.

[62]  J. Flaws,et al.  Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle. , 1995, Endocrinology.

[63]  G. Cooper,et al.  Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. , 1995, Science.

[64]  A. Levitzki,et al.  Tyrosine kinase inhibition: an approach to drug development. , 1995, Science.

[65]  R. Cowan,et al.  Fas antigen-mediated apoptosis in human granulosa/luteal cells. , 1995, Biology of reproduction.

[66]  J. Tilly,et al.  Gonadotropin suppression of apoptosis in cultured preovulatory follicles: mediatory role of endogenous insulin-like growth factor I. , 1994, Endocrinology.

[67]  J. Pierce,et al.  The alpha PDGFR tyrosine kinase mediates locomotion of two different cell types through chemotaxis and chemokinesis. , 1994, Biochemical and biophysical research communications.

[68]  Philippe Soriano,et al.  Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. , 1994, Genes & development.

[69]  B Swolin,et al.  Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities. , 1994, Genes & development.

[70]  L. Tartaglia,et al.  A novel domain within the 55 kd TNF receptor signals cell death , 1993, Cell.

[71]  C. Thompson,et al.  bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death , 1993, Cell.

[72]  S. Korsmeyer,et al.  Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death , 1993, Cell.

[73]  J. Tilly,et al.  Epidermal growth factor and basic fibroblast growth factor suppress the spontaneous onset of apoptosis in cultured rat ovarian granulosa cells and follicles by a tyrosine kinase-dependent mechanism. , 1992, Molecular endocrinology.

[74]  B. Gangrade,et al.  The regulation of porcine theca cell proliferation in vitro: synergistic actions of epidermal growth factor and platelet-derived growth factor. , 1992, Endocrinology.

[75]  F. Hughes,et al.  Biochemical identification of apoptosis (programmed cell death) in granulosa cells: evidence for a potential mechanism underlying follicular atresia. , 1991, Endocrinology.

[76]  N. Dhanasekaran,et al.  Studies on follicular atresia: role of gonadotropins and gonadal steroids in regulating cathepsin-D activity of preovulatory follicles in the rat , 1989, Molecular and Cellular Endocrinology.

[77]  N B Schwartz,et al.  Dynamic changes in inhibin messenger RNAs in rat ovarian follicles during the reproductive cycle. , 1988, Science.

[78]  T. Deuel,et al.  Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors , 1984, Cell.

[79]  Honghong Yao,et al.  Platelet-derived growth factor protects neurons against gp120-mediated toxicity , 2011, Journal of NeuroVirology.

[80]  M. Skinner,et al.  Platelet-derived growth factor modulates the primordial to primary follicle transition. , 2006, Reproduction.

[81]  Se-Jin Yoon,et al.  Gene expression profiling of early follicular development in primordial, primary, and secondary follicles. , 2006, Fertility and sterility.

[82]  A. Johnson,et al.  Expression of members of the bcl-2 gene family in the immature rat ovary: equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive bcl-2 and bcl-xlong messenger ribonucleic acid levels. , 1995, Endocrinology.

[83]  G. Erickson,et al.  Evidence for widespread atresia in the hypophysectomized estrogen-treated rat. , 1987, Endocrinology.