Prostaglandin E2 accelerates invasion by upregulating Snail in hepatocellular carcinoma cells

[1]  D. Xie,et al.  Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial‐mesenchymal transition by way of Akt/GSK‐3β/Snail signaling , 2014, Hepatology.

[2]  E. Elinav,et al.  Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms , 2013, Nature Reviews Cancer.

[3]  D. Rosenberg,et al.  Multifaceted roles of PGE2 in inflammation and cancer , 2013, Seminars in Immunopathology.

[4]  H. Ahmed,et al.  Immunohistochemical expression of COX2 and iNOS in bladder cancer and its association with urinary schistosomiasis among Sudanese patients , 2013, Infectious Agents and Cancer.

[5]  Takuji Tanaka.  Introduction for inflammation and cancer , 2013, Seminars in Immunopathology.

[6]  B. Hemmings,et al.  PI3K-PKB/Akt pathway. , 2012, Cold Spring Harbor perspectives in biology.

[7]  Jun Liang,et al.  Transcriptional repressor snail and metastasis in hepatocellular carcinoma. , 2012, Hepato-gastroenterology.

[8]  Aiju Fang,et al.  High co-expression of vascular endothelial growth factor receptor-1 and Snail is associated with poor prognosis after curative resection of hepatocellular carcinoma , 2012, Medical Oncology.

[9]  W. Guo,et al.  MicroRNA‐9 up‐regulates E‐cadherin through inhibition of NF‐κB1–Snail1 pathway in melanoma , 2012, The Journal of pathology.

[10]  Hye-Nan Kim,et al.  Modulation of PGE2-induced EP4 expression on snail signaling and the impact on epithelial-mesenchymal transition: significance of EP4 antagonism. , 2011, Anticancer research.

[11]  E. P. Chen,et al.  COX-2 and PGE2-dependent immunomodulation in breast cancer. , 2011, Prostaglandins & other lipid mediators.

[12]  M. Hou,et al.  Clinical significance of Cox-2, Survivin and Bcl-2 expression in hepatocellular carcinoma (HCC) , 2011, Medical oncology.

[13]  H. Shigeishi,et al.  PGE₂ targets squamous cell carcinoma cell with the activated epidermal growth factor receptor family for survival against 5-fluorouracil through NR4A2 induction. , 2011, Cancer letters.

[14]  T. Ishikawa,et al.  Activation of epidermal growth factor receptor signaling by the prostaglandin E2 receptor EP4 pathway during gastric tumorigenesis , 2011, Cancer science.

[15]  S. Bae,et al.  Clinicopathologic significance of the expression of Snail in hepatocellular carcinoma , 2011, The Korean journal of hepatology.

[16]  C. Liebmann.  EGF receptor activation by GPCRs: An universal pathway reveals different versions , 2011, Molecular and Cellular Endocrinology.

[17]  A. Rana,et al.  Glycogen Synthase Kinase-3beta regulates Snail and beta-catenin during gastrin-induced migration of gastric cancer cells , 2010, Journal of molecular signaling.

[18]  Hideo Baba,et al.  Epithelial–mesenchymal transition in cancer development and its clinical significance , 2010, Cancer science.

[19]  T. Peng,et al.  Prostaglandin E2 upregulates survivin expression via the EP1 receptor in hepatocellular carcinoma cells. , 2010, Life sciences.

[20]  T. Jang,et al.  Cyclooxygenase-2 Expression Is Related to the Epithelial-to-Mesenchymal Transition in Human Colon Cancers , 2009, Yonsei medical journal.

[21]  D. Fitzgerald,et al.  Proneoplastic effects of PGE2 mediated by EP4 receptor in colorectal cancer , 2009, BMC Cancer.

[22]  E. Lander,et al.  Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. , 2008, Cancer research.

[23]  P. Clark,et al.  Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis. , 2008, Cancer research.

[24]  L. Nelles,et al.  Activation of NF-κB by Akt upregulates Snail expression and induces epithelium mesenchyme transition , 2007, Oncogene.

[25]  B. Doble,et al.  Role of Glycogen Synthase Kinase-3 in Cell Fate and Epithelial-Mesenchymal Transitions , 2007, Cells Tissues Organs.

[26]  S. Narumiya,et al.  Prostaglandin E Receptors* , 2007, Journal of Biological Chemistry.

[27]  Tong Wu,et al.  Cyclooxygenase-2 in hepatocellular carcinoma. , 2006, Cancer treatment reviews.

[28]  K. T. Patton,et al.  Decreased annexin I expression in prostatic adenocarcinoma and in high‐grade prostatic intraepithelial neoplasia , 2005, Histopathology.

[29]  S. Dey,et al.  Prostaglandin E2 enhances intestinal adenoma growth via activation of the Ras-mitogen-activated protein kinase cascade. , 2005, Cancer research.

[30]  M. Hung,et al.  Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition , 2004, Nature Cell Biology.

[31]  S. Dedhar,et al.  Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells , 2004, Oncogene.

[32]  R. DuBois,et al.  Prostaglandin E2 Regulates Cell Migration via the Intracellular Activation of the Epidermal Growth Factor Receptor* , 2003, Journal of Biological Chemistry.

[33]  G. Michalopoulos,et al.  Cyclooxygenase‐2 promotes hepatocellular carcinoma cell growth through AKT activation: Evidence for AKT inhibition in celecoxib‐induced apoptosis , 2003, Hepatology.

[34]  M. Nieto,et al.  The snail superfamily of zinc-finger transcription factors , 2002, Nature Reviews Molecular Cell Biology.

[35]  K. Miyazaki,et al.  Inverse correlation between E-cadherin and Snail expression in hepatocellular carcinoma cell lines in vitro and in vivo , 2002, British Journal of Cancer.

[36]  L. Pfeffer,et al.  NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase , 1999, Nature.

[37]  K. Guan,et al.  Negative Regulation of the Forkhead Transcription Factor FKHR by Akt* , 1999, The Journal of Biological Chemistry.

[38]  M. Greenberg,et al.  Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor , 1999, Cell.

[39]  M. Montminy,et al.  CREB Is a Regulatory Target for the Protein Kinase Akt/PKB* , 1998, The Journal of Biological Chemistry.

[40]  P. Dijkman,et al.  Lipid-dependent GPCR dimerization. , 2013, Methods in cell biology.

[41]  T. Wen,et al.  Risk factors of ascites after hepatectomy for patients with hepatocellular carcinoma and hepatitis B virus-associated cirrhosis. , 2012, Hepato-gastroenterology.

[42]  R. DuBois,et al.  Prostaglandin E 2 Regulates Cell Migration via the Intracellular Activation of the Epidermal Growth Factor Receptor* , 2003 .

[43]  H. Kawasaki,et al.  Cyclooxygenase-2 expression in hepatocellular carcinoma. , 1999, Hepato-gastroenterology.