A Systematic Analysis of Mosquito-Microbiome Biosynthetic Gene Clusters Reveals Antimalarial Siderophores that Reduce Mosquito Reproduction Capacity.

[1]  E. Derbyshire,et al.  Coculturing of Mosquito‐Microbiome Bacteria Promotes Heme Degradation in Elizabethkingia anophelis , 2019, Chembiochem : a European journal of chemical biology.

[2]  A. Diabaté,et al.  Transgenic Metarhizium rapidly kills mosquitoes in a malaria-endemic region of Burkina Faso , 2019, Science.

[3]  Philip F. Hughes,et al.  Plasmodium PK9 Inhibitors Promote Growth of Liver-Stage Parasites. , 2019, Cell chemical biology.

[4]  L. Vosshall,et al.  Small-Molecule Agonists of Ae. aegypti Neuropeptide Y Receptor Block Mosquito Biting , 2019, Cell.

[5]  D. Lampe,et al.  Blood meal-induced inhibition of vector-borne disease by transgenic microbiota , 2018, Nature Communications.

[6]  P. Dorrestein,et al.  Identification of the Bacterial Biosynthetic Gene Clusters of the Oral Microbiome Illuminates the Unexplored Social Language of Bacteria during Health and Disease , 2018, mBio.

[7]  Daniel B. Müller,et al.  Bipartite interactions, antibiotic production and biosynthetic potential of the Arabidopsis leaf microbiome , 2018, Nature Microbiology.

[8]  J. Sacchettini,et al.  Discovery of Antimicrobial Lipodepsipeptides Produced by a Serratia sp. within Mosquito Microbiomes , 2018, Chembiochem : a European journal of chemical biology.

[9]  S. Brady,et al.  Accessing Bioactive Natural Products from the Human Microbiome. , 2018, Cell host & microbe.

[10]  C. Townsend,et al.  Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin , 2018, Scientific Reports.

[11]  Marnix H. Medema,et al.  Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology , 2018, mSystems.

[12]  H. Bode,et al.  Identification and occurrence of the hydroxamate siderophores aerobactin, putrebactin, avaroferrin and ochrobactin C as virulence factors from entomopathogenic bacteria , 2017, Environmental microbiology.

[13]  P. Agre,et al.  Driving mosquito refractoriness to Plasmodium falciparum with engineered symbiotic bacteria , 2017, Science.

[14]  T. Böttcher,et al.  One Enzyme, Three Metabolites: Shewanella algae Controls Siderophore Production via the Cellular Substrate Pool. , 2017, Cell chemical biology.

[15]  Kai Blin,et al.  antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification , 2017, Nucleic Acids Res..

[16]  J. Clardy,et al.  Macrotermycins A-D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39. , 2017, Organic letters.

[17]  Mark R. Brown,et al.  Mosquitoes host communities of bacteria that are essential for development but vary greatly between local habitats , 2016, Molecular ecology.

[18]  Benito Munoz,et al.  Diversity-oriented synthesis yields novel multistage antimalarial inhibitors , 2016, Nature.

[19]  M. Poulsen,et al.  Natural products from microbes associated with insects , 2016, Beilstein journal of organic chemistry.

[20]  Carla S. Jones,et al.  Minimum Information about a Biosynthetic Gene cluster. , 2015, Nature chemical biology.

[21]  A. Vilcinskas,et al.  A Photorhabdus Natural Product Inhibits Insect Juvenile Hormone Epoxide Hydrolase , 2015, Chembiochem : a European journal of chemical biology.

[22]  Elizabeth M. Nolan,et al.  Beyond iron: non-classical biological functions of bacterial siderophores. , 2015, Dalton transactions.

[23]  M. Jacobs-Lorena,et al.  Antimalarial Iron Chelator FBS0701 Blocks Transmission by Plasmodium falciparum Gametocyte Activation Inhibition , 2014, Antimicrobial Agents and Chemotherapy.

[24]  G. Dimopoulos,et al.  Chromobacterium Csp_P Reduces Malaria and Dengue Infection in Vector Mosquitoes and Has Entomopathogenic and In Vitro Anti-pathogen Activities , 2014, PLoS pathogens.

[25]  Peter Cimermancic,et al.  A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics , 2014, Cell.

[26]  Roger G. Linington,et al.  Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters , 2014, Cell.

[27]  Mark R. Brown,et al.  Mosquitoes rely on their gut microbiota for development , 2014, Molecular ecology.

[28]  J. Clardy,et al.  A chimeric siderophore halts swarming Vibrio. , 2014, Angewandte Chemie.

[29]  D. Neafsey,et al.  Genetic Dissection of Anopheles gambiae Gut Epithelial Responses to Serratia marcescens , 2014, PLoS pathogens.

[30]  H. Bode,et al.  Rhabdopeptides as Insect‐Specific Virulence Factors from Entomopathogenic Bacteria , 2013, Chembiochem : a European journal of chemical biology.

[31]  Jiannong Xu,et al.  Depletion of ribosomal RNA for mosquito gut metagenomic RNA-seq. , 2013, Journal of visualized experiments : JoVE.

[32]  J. Clardy,et al.  Antibiotic and Antimalarial Quinones from Fungus-Growing Ant-Associated Pseudonocardia sp. , 2012, Journal of natural products.

[33]  H. Vlamakis,et al.  Mixing and Matching Siderophore Clusters: Structure and Biosynthesis of Serratiochelins from Serratia sp. V4 , 2012, Journal of the American Chemical Society.

[34]  J. Clardy,et al.  Microtermolides A and B from Termite-Associated Streptomyces sp. and Structural Revision of Vinylamycin , 2012, Organic letters.

[35]  Miguel Prudêncio,et al.  Liver-stage malaria parasites vulnerable to diverse chemical scaffolds , 2012, Proceedings of the National Academy of Sciences.

[36]  M. Nei,et al.  MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. , 2011, Molecular biology and evolution.

[37]  Ying Wang,et al.  Dynamic Gut Microbiome across Life History of the Malaria Mosquito Anopheles gambiae in Kenya , 2011, PloS one.

[38]  G. Dimopoulos,et al.  Natural Microbe-Mediated Refractoriness to Plasmodium Infection in Anopheles gambiae , 2011, Science.

[39]  Bernd Schneider,et al.  Symbiotic Streptomycetes provide antibiotic combination prophylaxis for wasp offspring. , 2010, Nature chemical biology.

[40]  Azar Radfar,et al.  Synchronous culture of Plasmodium falciparum at high parasitemia levels , 2009, Nature Protocols.

[41]  V. S. Nam,et al.  Characterizing the Aedes aegypti Population in a Vietnamese Village in Preparation for a Wolbachia-Based Mosquito Control Strategy to Eliminate Dengue , 2009, PLoS neglected tropical diseases.

[42]  D. Gubler,et al.  Vector-borne diseases. , 2009, Revue scientifique et technique.

[43]  Dong-Chan Oh,et al.  Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis. , 2009, Nature chemical biology.

[44]  R. Abagyan,et al.  XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. , 2006, Analytical chemistry.

[45]  Robert C. Edgar,et al.  MUSCLE: multiple sequence alignment with high accuracy and high throughput. , 2004, Nucleic acids research.

[46]  R. Sinden,et al.  The dynamics of interactions between Plasmodium and the mosquito: a study of the infectivity of Plasmodium berghei and Plasmodium gallinaceum, and their transmission by Anopheles stephensi, Anopheles gambiae and Aedes aegypti. , 2003, International journal for parasitology.

[47]  J. Ravel,et al.  Genomics of pyoverdine-mediated iron uptake in pseudomonads. , 2003, Trends in microbiology.

[48]  G. Jung,et al.  Bisucaberin – A dihydroxamate siderophore isolated from Vibrio salmonicida, an important pathogen of farmed Atlantic salmon (Salmo salar) , 2002, Biometals.

[49]  Thomas L. Madden,et al.  Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.

[50]  J. Koella,et al.  Variability in the relationship between weight and wing length of Anopheles gambiae (Diptera: Culicidae). , 1996, Journal of medical entomology.

[51]  H. Budzikiewicz,et al.  Serratiochelin, a New Catecholate Siderophore from Serratia marcescens , 1994 .

[52]  A. Butler,et al.  Aerobactin production by a planktonic marine Vibrio sp , 1993 .

[53]  C. Atkinson,et al.  Stage-specific ultrastructural effects of desferrioxamine on Plasmodium falciparum in vitro. , 1991, The American journal of tropical medicine and hygiene.

[54]  S. Lytton,et al.  Reversed siderophores act as antimalarial agents. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[55]  H. Naganawa,et al.  Bisucaberin, a new siderophore, sensitizing tumor cells to macrophage-mediated cytolysis. II. Physico-chemical properties and structure determination. , 1987, The Journal of antibiotics.

[56]  D. Spira,et al.  Plasmodium vinckei: suppression of mouse infections with desferrioxamine B. , 1985, Experimental parasitology.

[57]  J. C. Cook,et al.  Pyochelin: novel structure of an iron-chelating growth promoter for Pseudomonas aeruginosa. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[58]  M. Kajla Symbiotic Bacteria as Potential Agents for Mosquito Control. , 2019, Trends in parasitology.

[59]  J. Neilands,et al.  Universal chemical assay for the detection and determination of siderophores. , 1987, Analytical biochemistry.

[60]  C. E. Lankford,et al.  Bacterial Assimilation of iron , 1973 .