Outcomes of therapy‐related acute lymphoblastic leukemia in adults after allogeneic stem cell transplantation

Therapy‐related acute lymphoblastic leukemia (t‐ALL) is an increasingly recognized subset of therapy‐related acute leukemia. There are limited data on the role of allogeneic hematopoietic stem cell transplantation (HSCT) in t‐ALL. Recent reports suggest comparable outcomes of t‐ALL with de novo ALL after HSCT.

[1]  R. Larson,et al.  Therapy-related acute lymphoblastic leukemia is a distinct entity with adverse genetic features and clinical outcomes. , 2019, Blood advances.

[2]  U. Borate,et al.  Representation of therapy-related myelodysplastic syndrome in clinical trials over the past 20 years. , 2019, Blood advances.

[3]  J. Ribera Therapy-related acute lymphoblastic leukemia , 2018, Haematologica.

[4]  T. Slavin,et al.  Therapy-related acute lymphoblastic leukemia has distinct clinical and cytogenetic features compared to de novo acute lymphoblastic leukemia, but outcomes are comparable in transplanted patients , 2018, Haematologica.

[5]  A. Chanan-Khan,et al.  Second primary acute lymphoblastic leukemia in adults: a SEER analysis of incidence and outcomes , 2017, Cancer medicine.

[6]  J. Paulus,et al.  Secondary acute lymphoblastic leukemia is a distinct clinical entity with prognostic significance , 2017, Blood Cancer Journal.

[7]  G. Marcucci,et al.  Philadelphia chromosome as a recurrent event among therapy‐related acute leukemia , 2017, American journal of hematology.

[8]  J. Hernández-Rivas,et al.  Incidence, clinical and biological characteristics and outcome of secondary acute lymphoblastic leukemia after solid organ or hematologic malignancy , 2016, Leukemia & lymphoma.

[9]  V. Bhatt,et al.  Secondary acute lymphoblastic leukemia is an independent predictor of poor prognosis. , 2015, Leukemia research.

[10]  U. Borate,et al.  Therapy‐related B‐lymphoblastic leukemia associated with Philadelphia chromosome and MLL rearrangement: Single institution experience and the review of the literature , 2015, Pathology international.

[11]  M. Nørgaard,et al.  Epidemiology and Clinical Significance of Secondary and Therapy-Related Acute Myeloid Leukemia: A National Population-Based Cohort Study. , 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[12]  S. Devlin,et al.  Secondary acute lymphoblastic leukaemia is constitutional and probably not related to prior therapy , 2015, British journal of haematology.

[13]  I. Aldoss,et al.  Therapy-related ALL: cytogenetic features and hematopoietic cell transplantation outcome , 2015, Bone Marrow Transplantation.

[14]  S. Kamel‐Reid,et al.  Therapy‐related acute lymphoblastic leukemia is more frequent than previously recognized and has a poor prognosis , 2012, Cancer.

[15]  H. Kantarjian,et al.  Precursor B-acute lymphoblastic leukemia occurring in patients with a history of prior malignancies: is it therapy-related? , 2012, Haematologica.

[16]  A. Bagg Therapy-associated Lymphoid Proliferations , 2011, Advances in anatomic pathology.

[17]  K. Döhner,et al.  The impact of therapy-related acute myeloid leukemia (AML) on outcome in 2853 adult patients with newly diagnosed AML. , 2011, Blood.

[18]  G. Wilding,et al.  Biologic features and treatment outcome of secondary acute lymphoblastic leukemia--a review of 101 cases. , 2008, Annals of oncology : official journal of the European Society for Medical Oncology.

[19]  M. Tallman,et al.  In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: fin , 2006, Blood.

[20]  V. Diehl,et al.  Outcome of allogeneic hematopoietic stem-cell transplantation in adult patients with acute lymphoblastic leukemia: no difference in related compared with unrelated transplant in first complete remission. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  M. Slovak,et al.  High frequency of pro-B acute lymphoblastic leukemia in adults with secondary leukemia with 11q23 abnormalities , 2003, Leukemia.

[22]  S. Chevret,et al.  Allogeneic bone marrow transplantation for therapy-related myelodysplastic syndrome and acute myeloid leukemia: a long-term study of 70 patients-report of the French society of bone marrow transplantation. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  F. Mandelli,et al.  Acute lymphoblastic leukaemia occurring as second malignancy: report of the GIMEMA Archive of Adult Acute Leukaemia , 1999 .