A soft 3D polyacrylate hydrogel recapitulates the cartilage niche and allows growth-factor free tissue engineering of human articular cartilage.

[1]  R. Reis,et al.  Combinatory approach for developing silk fibroin scaffolds for cartilage regeneration. , 2018, Acta biomaterialia.

[2]  M. Kurup,et al.  Biocompatibility of subcutaneously implanted marine macromolecules cross-linked bio-composite scaffold for cartilage tissue engineering applications , 2018, Journal of biomaterials science. Polymer edition.

[3]  C. Carda,et al.  Biostable Scaffolds of Polyacrylate Polymers Implanted in the Articular Cartilage Induce Hyaline-Like Cartilage Regeneration in Rabbits , 2017, The International journal of artificial organs.

[4]  S. Ferguson,et al.  Direct electrospinning of 3D auricle-shaped scaffolds for tissue engineering applications , 2016, Biofabrication.

[5]  J. Marchal,et al.  Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes , 2015, Scientific Reports.

[6]  David J Scurr,et al.  High throughput screening for biomaterials discovery. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[7]  S. Bryant,et al.  Semi-interpenetrating networks of hyaluronic acid in degradable PEG hydrogels for cartilage tissue engineering. , 2014, Acta biomaterialia.

[8]  L. Krishnan,et al.  Relating pore size variation of poly (ɛ-caprolactone) scaffolds to molecular weight of porogen and evaluation of scaffold properties after degradation. , 2014, Journal of biomedical materials research. Part B, Applied biomaterials.

[9]  J. W. Lee,et al.  microRNA-495 inhibits chondrogenic differentiation in human mesenchymal stem cells by targeting Sox9. , 2014, Stem cells and development.

[10]  Xi Liang,et al.  Sox9 Potentiates BMP2-Induced Chondrogenic Differentiation and Inhibits BMP2-Induced Osteogenic Differentiation , 2014, PloS one.

[11]  Rachel L. Williams,et al.  Induction of mesenchymal stem cell chondrogenesis by polyacrylate substrates , 2013, Acta biomaterialia.

[12]  J. Mano,et al.  Different hyaluronic acid morphology modulates primary articular chondrocyte behavior in hyaluronic acid-coated polycaprolactone scaffolds. , 2013, Journal of biomedical materials research. Part A.

[13]  D. Seliktar.  Designing Cell-Compatible Hydrogels for Biomedical Applications , 2012, Science.

[14]  João Rodrigues,et al.  Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications. , 2012, Chemical Society reviews.

[15]  P. Gatenholm,et al.  Influence of pore size on the redifferentiation potential of human articular chondrocytes in poly(urethane urea) scaffolds , 2011, Journal of tissue engineering and regenerative medicine.

[16]  F. L. Ng,et al.  Development of porous polymer monolith by photoinitiated polymerization , 2011 .

[17]  C. Bünger,et al.  Combined 3D and hypoxic culture improves cartilage-specific gene expression in human chondrocytes , 2011, Acta orthopaedica.

[18]  Sean P. Palecek,et al.  Development of macroporous poly(ethylene glycol) hydrogel arrays within microfluidic channels. , 2010, Biomacromolecules.

[19]  W. Richter,et al.  Autologous Chondrocyte Implantation Using the Original Periosteum-Cover Technique versus Matrix-Associated Autologous Chondrocyte Implantation , 2010, The American journal of sports medicine.

[20]  Ali Khademhosseini,et al.  Controlling the porosity and microarchitecture of hydrogels for tissue engineering. , 2010, Tissue engineering. Part B, Reviews.

[21]  Mark Bradley,et al.  Strategies for cell manipulation and skeletal tissue engineering using high-throughput polymer blend formulation and microarray techniques. , 2010, Biomaterials.

[22]  J. L. Gomez Ribelles,et al.  In Vivo Evaluation of 3-Dimensional Polycaprolactone Scaffolds for Cartilage Repair in Rabbits , 2010, The American journal of sports medicine.

[23]  Rong-Nan Huang,et al.  Effect of recombinant galectin-1 on the growth of immortal rat chondrocyte on chitosan-coated PLGA scaffold. , 2009, Journal of biomedical materials research. Part A.

[24]  A. Bhosale,et al.  Articular cartilage: structure, injuries and review of management , 2008 .

[25]  N. Kregar-Velikonja,et al.  Quantitative analysis of gene expression in human articular chondrocytes assigned for autologous implantation , 2008, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[26]  M. Brittberg.  Autologous chondrocyte implantation--technique and long-term follow-up. , 2008, Injury.

[27]  Jason A Burdick,et al.  Engineering cartilage tissue. , 2008, Advanced drug delivery reviews.

[28]  S. Gerecht,et al.  A porous photocurable elastomer for cell encapsulation and culture. , 2007, Biomaterials.

[29]  M. Dauner,et al.  Chondrogenic differentiation of human articular chondrocytes differs in biodegradable PGA/PLA scaffolds. , 2007, Tissue engineering.

[30]  T. Takato,et al.  Three-dimensional microenvironments retain chondrocyte phenotypes during proliferation culture. , 2007, Tissue engineering.

[31]  A. Khademhosseini,et al.  Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology , 2006 .

[32]  J A Skinner,et al.  Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a prospective, randomised study. , 2005, The Journal of bone and joint surgery. British volume.

[33]  Hyeon-Joo Kim,et al.  Potential predictive markers for proliferative capacity of cultured human articular chondrocytes: PCNA and p21. , 2005, Artificial organs.

[34]  M. Truppe,et al.  Changes in the ratio of type-I and type-II collagen expression during monolayer culture of human chondrocytes. , 2004, The Journal of bone and joint surgery. British volume.

[35]  Steven B Cohen,et al.  The use of absorbable co-polymer pads with alginate and cells for articular cartilage repair in rabbits. , 2003, Biomaterials.

[36]  Scott C. Brown,et al.  A three-dimensional osteochondral composite scaffold for articular cartilage repair. , 2002, Biomaterials.

[37]  K. Leong,et al.  The design of scaffolds for use in tissue engineering. Part I. Traditional factors. , 2001, Tissue engineering.

[38]  L G Griffith,et al.  Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition. , 2001, Tissue engineering.

[39]  F. Luyten,et al.  Molecular markers predictive of the capacity of expanded human articular chondrocytes to form stable cartilage in vivo. , 2001, Arthritis and rheumatism.

[40]  D. Hutmacher,et al.  Scaffolds in tissue engineering bone and cartilage. , 2000, Biomaterials.

[41]  M. Taya,et al.  Pores and diffusion characteristics of porous gels , 2000 .

[42]  D. Salter.  The Tissues we deal with II: Cartilage , 1998 .

[43]  C B Sledge,et al.  Matrix collagen type and pore size influence behaviour of seeded canine chondrocytes. , 1997, Biomaterials.

[44]  C. Ohlsson,et al.  Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. , 1994, The New England journal of medicine.

[45]  Jerry C. Hu,et al.  Repair and tissue engineering techniques for articular cartilage , 2015, Nature Reviews Rheumatology.

[46]  S. Hsu,et al.  Evaluation of biodegradable elastic scaffolds made of anionic polyurethane for cartilage tissue engineering. , 2015, Colloids and surfaces. B, Biointerfaces.

[47]  M. Perán,et al.  Chondrocytes extract from patients with osteoarthritis induces chondrogenesis in infrapatellar fat pad-derived stem cells. , 2013, Osteoarthritis and cartilage.

[48]  Salvatore Pernagallo,et al.  Polymer microarrays for cellular high-content screening. , 2011, Methods in molecular biology.

[49]  Robert Langer,et al.  High throughput methods applied in biomaterial development and discovery. , 2010, Biomaterials.

[50]  Mark Bradley,et al.  High‐Throughput Evaluation of the Wettability of Polymer Libraries , 2004 .

[51]  V Vécsei,et al.  Dedifferentiation-associated changes in morphology and gene expression in primary human articular chondrocytes in cell culture. , 2002, Osteoarthritis and cartilage.

[52]  M. Kino‐oka,et al.  Evaluation of attachment and growth of anchorage-dependent cells on culture surfaces with type I collagen coating. , 2001, Journal of bioscience and bioengineering.