Synthesis and Reactivity of 7-Azaindole (1H-Pyrrolo[2,3-b]pyridine)

[1]  R. Ruel,et al.  Concise and efficient synthesis of 4-fluoro-1H-pyrrolo[2,3-b]pyridine. , 2003, Organic letters.

[2]  M. Mahon,et al.  The synthesis and late transition metal chemistry of 7-aza-N-indolyl phosphines and the activity of their palladium complexes in CO–ethene co-polymerisation , 2003 .

[3]  F. Albericio,et al.  Total syntheses of variolin B and deoxyvariolin B. , 2003, The Journal of organic chemistry.

[4]  Zheng Yang,et al.  Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions. , 2003, Journal of medicinal chemistry.

[5]  G. Deacon,et al.  Unexpected Formation of Bis(1H‐7‐azaindol‐3‐yl)(2,4,5‐trimethylphenyl)methane by Erbium Metal‐Induced CH Activation , 2003 .

[6]  S. Emanuel,et al.  Synthesis and discovery of macrocyclic polyoxygenated bis-7-azaindolylmaleimides as a novel series of potent and highly selective glycogen synthase kinase-3beta inhibitors. , 2003, Journal of medicinal chemistry.

[7]  F. Albericio,et al.  Synthesis of variolin B , 2003 .

[8]  S. Buchwald,et al.  Ipso- or cine-substitutions of 6-haloimidazo[1,2-a]pyridine derivatives with different azoles depending on the reaction conditions. , 2003, The Journal of organic chemistry.

[9]  P. Renard,et al.  Synthesis of isogranulatimides A and B analogues possessing a 7-azaindole unit instead of an indole moiety , 2003 .

[10]  J. M. Lluch,et al.  A theoretical study of the ground and first excited singlet state proton transfer reaction in isolated 7-azaindole–water complexes , 2003 .

[11]  Suning Wang,et al.  Benzene C-H activation by Two isomeric platinum(II) complexes of bis(N-7-azaindolyl)methane , 2003 .

[12]  M. Viaud-Massuard,et al.  Synthesis of New Melatonin Analogues from Dimers of Azaindole and Indole by Use of Suzuki Homocoupling , 2003 .

[13]  P. Renard,et al.  Syntheses and antiproliferative activities of rebeccamycin analogues bearing two 7-azaindole moieties. , 2003, Bioorganic & medicinal chemistry.

[14]  P. Knochel,et al.  Synthesis of polyfunctional indoles and related heterocycles mediated by cesium and potassium bases , 2003 .

[15]  Giuseppe Zampella,et al.  A practical synthesis of 7-azaindolylcarboxy-endo-tropanamide (DF 1012) , 2003 .

[16]  M. Prudhomme Rebeccamycin analogues as anti-cancer agents. , 2003, European journal of medicinal chemistry.

[17]  P. Molina,et al.  Carbodiimide-mediated preparation of the tricyclic pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine ring system and its application to the synthesis of the potent antitumoral marine alkaloid variolin B and analog. , 2003, The Journal of organic chemistry.

[18]  C. Bailly,et al.  Syntheses and antiproliferative activities of 7-azarebeccamycin analogues bearing one 7-azaindole moiety. , 2003, Journal of medicinal chemistry.

[19]  Wan Yong-xian,et al.  Radiosynthesis of 3-{[4-(4-[18F]fluorobenzyl)]piperazin-1-yl}methyl-1H-pyrrolo[2,3-b]pyridine: A potential dopamine D4 receptor imaging agent , 2003 .

[20]  M. V. R. D. Souza,et al.  Síntese e reatividade de azaindóis: aplicações na preparação de moléculas de interesse biológico , 2002 .

[21]  Suning Wang,et al.  Isomerism of bis(7-azaindolyl)methane. , 2002, Organic letters.

[22]  Hongtao Yu,et al.  Synthesis and fluorescence study of 7-azaindole in DNA oligonucleotides replacing a purine base. , 2002, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

[23]  Suning Wang,et al.  Diplatinum-Center-Mediated Transformation of a Substituted Benzene to a Cyclohexadienyl Dianion and the Breaking of C−Cl Bonds: Syntheses and Structures of Pt2R4(ttab) and Pt2(CH3)4(ttab)Cl2 , 2002 .

[24]  Antonio Martín,et al.  Synthesis of a Dinuclear Platinum−Silver Complex Containing a Reactive Acetone Imine Prepared in Situ from Acetone and Ammonia and Stabilized by Metal Complexation , 2002 .

[25]  C. Bailly,et al.  Synthesis and biological evaluation of 7-azaindolocarbazoles , 2002 .

[26]  N. Meanwell,et al.  An effective procedure for the acylation of azaindoles at C-3. , 2002, The Journal of organic chemistry.

[27]  R. Borchardt,et al.  Synthesis of analogs of L-valacyclovir and determination of their substrate activity for the oligopeptide transporter in Caco-2 cells. , 2002, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[28]  T. Grönroos,et al.  Synthesis of 3-[[4-(4-[18F] fluorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine , 2002 .

[29]  Suning Wang,et al.  Novel Blue Phosphorescent Group 15 Compounds MR3 (M = P, Sb, Bi; R = p-(N-7-Azaindolyl)phenyl) , 2002 .

[30]  Suning Wang,et al.  Syntheses and photophysical properties of rigid-rod conjugated compounds based on N-7-azaindole and 2,2′-dipyridylamine , 2002 .

[31]  S. Routier,et al.  First synthesis of symmetrical and non-symmetrical aza indolocarbazoles derivatives , 2002 .

[32]  L. Schechter,et al.  Studies toward the discovery of the next generation of antidepressants. Part 2: incorporating a 5-HT(1A) antagonist component into a class of serotonin reuptake inhibitors. , 2002, Bioorganic & medicinal chemistry letters.

[33]  P. Molina,et al.  Synthesis of the potent antitumoral marine alkaloid variolin B , 2002 .

[34]  Jonathan C. Morris,et al.  Total synthesis of variolin B , 2001 .

[35]  J. Tatsugi,et al.  An improved preparation of isatins from indoles , 2001 .

[36]  F. Ujjainwalla,et al.  Total syntheses of 6- and 7-azaindole derived GnRH antagonists , 2001 .

[37]  Suning Wang,et al.  Syntheses and structures of new blue luminescent B(III) and Al(III) complexes: BPh2(acac-azain) and Al(CH3)(acac-azain)2, acac-azain=1-N-7-azaindolyl-1,3-butanedionato , 2001 .

[38]  K. Lackey,et al.  Synthesis of 5-Substituted 7-Azaoxindoles via Palladium-catalyzed Reactions , 2001 .

[39]  S. Okada,et al.  4-(Benzoylindolizinyl)butyric acids; novel nonsteroidal inhibitors of steroid 5alpha-reductase. III. , 2001, Chemical & pharmaceutical bulletin.

[40]  Suning Wang Luminescence and Electroluminescence of Al(III), B(III), Be(II) and Zn(II) Complexes with Nitrogen Donors , 2001 .

[41]  Cai-Guang Yang,et al.  Synthesis and cytotoxicity evaluation of novel indolylpyrimidines and indolylpyrazines as potential antitumor agents. , 2001, Bioorganic & medicinal chemistry.

[42]  P. Chou,et al.  Water-catalyzed excited-state double proton transfer in 3-cyano-7-azaindole: the resolution of the proton-transfer mechanism for 7-azaindoles in pure water. , 2001, Journal of the American Chemical Society.

[43]  P. Molina,et al.  Synthesis of the indole alkaloids meridianins from the tunicate Aplidium meridianum , 2001 .

[44]  J. Joule,et al.  Synthesis of deoxyvariolin B , 2001 .

[45]  Suning Wang,et al.  Novel blue luminescent/electroluminescent 7-azaindole derivatives: 1,3-Di(N-7-azaindolyl)benzene, 1-bromo-3,5-Di(N-7-azaindolyl)benzene, 1,3,5-Tri(N-7-azaindolyl)benzene, and 4,4'-Di(N-7-azaindolyl)biphenyl , 2001 .

[46]  Jean Martínez,et al.  Efficient chemoenzymatic synthesis of enantiomerically pure β-heterocyclic amino acid derivatives , 2000 .

[47]  Y. Tao,et al.  Blue-luminescent/electroluminescent Zn(II) compounds of 7-azaindole and N-(2-pyridyl)-7-azaindole: Zn(7-azaindole)2(CH3COO)2, Zn(NPA)(CH3COO)2, and Zn(NPA)((S)-(+)-CH3CH2CH(CH3)COO)2 (NPA = N-(2-pyridyl)-7-azaindole). , 2000, Inorganic chemistry.

[48]  Suning Wang,et al.  A Blue Luminescent Starburst Molecule and Its Orange Luminescent Trinuclear PdII Complex: 1,3,5-tris(7-azaindol-1-yl)benzene (tabH) and [Pd II3(tab)2 Cl4 ]. , 2000, Angewandte Chemie.

[49]  P. Knochel,et al.  Versatile Indole Synthesis by a 5-endo-dig Cyclization Mediated by Potassium or Cesium Bases. , 2000 .

[50]  P. Chou,et al.  Excited-State Double Proton Transfer in 3-Formyl-7-azaindole: Role of the nπ* State in Proton-Transfer Dynamics , 2000 .

[51]  Markus Berger,et al.  Efforts toward Expansion of the Genetic Alphabet: Optimization of Interbase Hydrophobic Interactions , 2000 .

[52]  Pi-Tai Chou,et al.  Excited-State Amine−Imine Double Proton Transfer in 7-Azaindoline , 2000 .

[53]  P. Molina,et al.  Synthetic studies towards the 2-aminopyrimidine alkaloids variolins and meridianins from marine origin , 2000 .

[54]  Y. Izawa,et al.  A Facile Synthesis of 1-Alkyl-7-azaisatins , 2000 .

[55]  Suning Wang,et al.  Syntheses, Structures, and Electroluminescence of New Blue/Green Luminescent Chelate Compounds: Zn(2-py-in)2(THF), BPh2(2-py-in), Be(2-py-in)2, and BPh2(2-py-aza) [2-py-in = 2-(2-pyridyl)indole; 2-py-aza = 2-(2-pyridyl)-7-azaindole] , 2000 .

[56]  Suning Wang,et al.  Syntheses, Structures, Solution, and Solid-State 27Al NMR Studies of Blue Luminescent Mononuclear Aluminum Complexes: Al(7-azain)2(7-azain-H)(CH3), Al(7-azain)3(7-azain-H), and Al(7-azain)(7-azain-H)(OCH(CF3)2)2 (7-azain-H = 7-azaindole) , 2000 .

[57]  A. Mouaddib,et al.  Synthesis of Indolo[3,2-c]quinoline and Pyrido[3′,2′ : 4,5] [3,2-c]quinoline Derivatives , 2000 .

[58]  J. Sebastião,et al.  Synthesis of β-substituted alanines via Michael addition of nucleophiles to dehydroalanine derivatives , 2000 .

[59]  H. Schoemaker,et al.  Synthesis and benzodiazepine receptor (ω receptor) affinities of 3-substituted derivatives of pyrrolo[2,3-c]pyridine-5-carboxylate, a novel class of ω1 selective ligands , 1999 .

[60]  J. Joule,et al.  Synthesis of 3-Aryl- and 3-Heteroaryl-7-azaindoles , 1999 .

[61]  G. Enright,et al.  Isomerism and Blue Electroluminescence of a Novel Organoboron Compound: BIII2 (O)(7-azain)2 Ph2. , 1999, Angewandte Chemie.

[62]  J. Teulade,et al.  Heterocyclic enaminones: Photochemical synthesis of 6,7,8,9-tetrahydro-5H-pyrido[2,3-b]indol-9-ones , 1999 .

[63]  G. Guillaumet,et al.  SYNTHESIS OF NEW MELATONINERGIC LIGANDS INCLUDING AZAINDOLE MOIETY , 1999 .

[64]  Yuguang Ma,et al.  A blue electroluminescent molecular device from a tetranucluear zinc(II) compound [Zn4O(AID)6] (AID = 7-azaindolate) , 1998 .

[65]  G. Jameson,et al.  Alkaloids from the antarctic sponge Kirkpatrickia varialosa. Part 2: Variolin A and N(3′)-methyl tetrahydrovariolin B , 1994 .

[66]  Sean Parkin,et al.  Alkaloids from the antarctic sponge Kirkpatrickia varialosa. , 1994 .

[67]  I. Mahadevan,et al.  Synthesis of pyrrolopyridines (azaindoles) , 1992 .

[68]  L. Zetta,et al.  C-Heteroarylation of sugars by indolylbromomagnesium salts. Synthesis of 3-(alditol-1-yl)indoles and their cyclization to indole C-nucleoside analogs , 1991 .

[69]  R. Larock,et al.  Synthesis of indoles via palladium-catalyzed heteroannulation of internal alkynes , 1991 .

[70]  C. Gálvez,et al.  Reactivity of 1H-pyrrolo[2,3-b]pyridine. I. Synthesis of 3-acetyl-7- azaindole and related compounds , 1982 .

[71]  P. G. Gassman,et al.  SPECIFIC ORTHO SUBSTITUTION OF AROMATIC HETEROCYCLIC AMINES, CONVERSIONS OF 2-AMINO-PYRIDINES , 1973 .

[72]  P. G. Gassman,et al.  Simple method for the conversion of anilines into 2-substituted indoles , 1973 .

[73]  M. M. Robison,et al.  7-Azaindole. III. Syntheses of 7-Aza Analogs of Some Biologically Significant Indole Derivatives1 , 1956 .

[74]  O. Kruber Zur Kenntnis der Basen des Steinkohlenteer‐Schweröls. Über das 7‐Aza‐indol im Steinkohlenteer , 1943 .