Parental hay fever reinforces IgE to pollen as pre‐clinical biomarker of hay fever in childhood

An early IgE response to grass or birch pollen can anticipate seasonal allergic rhinitis to pollen later in life or remain clinically silent.

[1]  P. Matricardi.  Allergen‐specific immunoprophylaxis: Toward secondary prevention of allergic rhinitis? , 2014, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[2]  E. Toskala,et al.  The link between parental allergy and offspring allergic and nonallergic rhinitis , 2013, Allergy.

[3]  P. Sly,et al.  Prophylactic use of sublingual allergen immunotherapy in high-risk children: a pilot study. , 2013, The Journal of allergy and clinical immunology.

[4]  P. Matricardi.  Molecular profile clustering of IgE responses and potential implications for specific immunotherapy , 2013, Current opinion in allergy and clinical immunology.

[5]  Kari Stefansson,et al.  Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization , 2013, Nature Genetics.

[6]  M. Wickman,et al.  Testing children for allergies: why, how, who and when , 2013, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[7]  T. Keil,et al.  Molecular spreading and predictive value of preclinical IgE response to Phleum pratense in children with hay fever. , 2012, The Journal of allergy and clinical immunology.

[8]  S. Holgate.  Innate and adaptive immune responses in asthma , 2012, Nature Medicine.

[9]  G. Weinmayr,et al.  Prediction of the incidence and persistence of allergic rhinitis in adolescence: a prospective cohort study. , 2012, The Journal of allergy and clinical immunology.

[10]  E. Toskala,et al.  Natural course and comorbidities of allergic and nonallergic rhinitis in children. , 2012, The Journal of allergy and clinical immunology.

[11]  P. Kuna,et al.  Subcutaneous immunotherapy and pharmacotherapy in seasonal allergic rhinitis: a comparison based on meta-analyses. , 2011, The Journal of allergy and clinical immunology.

[12]  A. Custovic,et al.  Allergen-specific IgG antibody levels modify the relationship between allergen-specific IgE and wheezing in childhood. , 2011, The Journal of allergy and clinical immunology.

[13]  B. Clarisse,et al.  Does allergic rhinitis exist in infancy? Findings from the PARIS birth cohort , 2011, Allergy.

[14]  M. Akdiş.  The cellular orchestra in skin allergy; are differences to lung and nose relevant? , 2010, Current opinion in allergy and clinical immunology.

[15]  B. Yawn,et al.  Development and implementation of guidelines in allergic rhinitis – an ARIA‐GA2LEN paper , 2010 .

[16]  S. Willich,et al.  The natural history of allergic rhinitis in childhood , 2010, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[17]  L. García-Marcos,et al.  Asthma and rhinoconjunctivitis comorbidity: United airway disease or inherited target organs? , 2010, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[18]  B. Niggemann,et al.  Dynamic evolution of serum immunoglobulin E to airborne allergens throughout childhood: results from the Multi‐Centre Allergy Study birth cohort , 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[19]  S. Durham,et al.  Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinoconjunctivitis. , 2006, The Journal of allergy and clinical immunology.

[20]  F. Martinez,et al.  Dynamic changes in sensitization to specific aeroallergens in children raised in a desert environment , 2004, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[21]  Wayne Thomas,et al.  Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[22]  S. Durham,et al.  Allergen immunotherapy: does it work and, if so, how and for how long? , 2000, Thorax.

[23]  U. Wahn,et al.  Long‐lasting sensitization to food during the first two years precedes allergic airway disease , 1998, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[24]  B. Cohen,et al.  Prevalence of IgE-Mediated Food Allergy Among Children With Atopic Dermatitis , 1998, Pediatrics.

[25]  D. Strachan,et al.  Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC) , 1997, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[26]  B. Wüthrich,et al.  Validation of a rhinitis symptom questionnaire (ISAAC core questions) in a population of Swiss school children visiting the school health services , 1997, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[27]  P. Holt.  A potential vaccine strategy for asthma and allied atopic diseases during early childhood , 1994, The Lancet.

[28]  U. Wahn,et al.  Atopic diseases in infancy. The German multicenter atopy study (MAS‐90) , 1994, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[29]  M. Wjst,et al.  Genetic risk for asthma, allergic rhinitis, and atopic dermatitis. , 1992, Archives of disease in childhood.

[30]  R. Green,et al.  THE BURDEN OF ALLERGIC RHINITIS , 2005 .