Equivalent titanium dioxide nanoparticle deposition by intratracheal instillation and whole body inhalation: the effect of dose rate on acute respiratory tract inflammation

[1]  Zhiwei Zhao,et al.  The impact of titanium dioxide nanoparticles on biological nitrogen removal from wastewater and bacterial community shifts in activated sludge , 2014, Biodegradation.

[2]  C. Bräuchle,et al.  Uptake kinetics and nanotoxicity of silica nanoparticles are cell type dependent. , 2013, Small.

[3]  R. Handy,et al.  Uptake of titanium from TiO2 nanoparticle exposure in the isolated perfused intestine of rainbow trout: nystatin, vanadate and novel CO2-sensitive components , 2013, Nanotoxicology.

[4]  Philip Demokritou,et al.  Interactions of engineered nanomaterials in physiological media and implications for in vitro dosimetry , 2013, Nanotoxicology.

[5]  Nianqiang Wu,et al.  Interlaboratory Evaluation of in Vitro Cytotoxicity and Inflammatory Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium , 2013, Environmental health perspectives.

[6]  A. Nel,et al.  Interlaboratory Evaluation of Rodent Pulmonary Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium , 2013, Environmental health perspectives.

[7]  É. Vivier,et al.  Les cellules natural killer - Adaptation et mémoire dans le système immunitaire inné , 2013 .

[8]  M. Ates,et al.  Effects of aqueous suspensions of titanium dioxide nanoparticles on Artemia salina: assessment of nanoparticle aggregation, accumulation, and toxicity , 2013, Environmental Monitoring and Assessment.

[9]  W. Kreyling,et al.  Pulmonary surfactant is indispensable in order to simulate the in vivo situation , 2013, Particle and Fibre Toxicology.

[10]  I. Kennedy,et al.  Novel lanthanide-labeled metal oxide nanoparticles improve the measurement of in vivo clearance and translocation , 2013, Particle and Fibre Toxicology.

[11]  Y. Morimoto,et al.  Comparison of dose-response relations between 4-week inhalation and intratracheal instillation of NiO nanoparticles using polimorphonuclear neutrophils in bronchoalveolar lavage fluid as a biomarker of pulmonary inflammation , 2013, Inhalation toxicology.

[12]  Inge Mangelsdorf,et al.  Change in agglomeration status and toxicokinetic fate of various nanoparticles in vivo following lung exposure in rats , 2012, Inhalation toxicology.

[13]  K. Mizuno,et al.  Pulmonary toxicity of well-dispersed multi-wall carbon nanotubes following inhalation and intratracheal instillation , 2012, Nanotoxicology.

[14]  Craig A Poland,et al.  Length-dependent pleural inflammation and parietal pleural responses after deposition of carbon nanotubes in the pulmonary airspaces of mice , 2012, Nanotoxicology.

[15]  Nicklas Raun Jacobsen,et al.  Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: Effects on liver DNA strand breaks in dams and offspring , 2012, Nanotoxicology.

[16]  L. Palmberg,et al.  Chemokine release by neutrophils in chronic obstructive pulmonary disease , 2012, Innate immunity.

[17]  Y. Morimoto,et al.  [Biological effect of fullerene (C60) to lung by inhalation or instillation]. , 2012, Journal of UOEH.

[18]  D. Girard,et al.  The Inflammatory Process in Response to Nanoparticles , 2011, TheScientificWorldJournal.

[19]  Mark R. Wiesner,et al.  Ultrasonic dispersion of nanoparticles for environmental, health and safety assessment – issues and recommendations , 2011, Nanotoxicology.

[20]  Y. Morimoto,et al.  Biopersistence of potassium hexatitanate in inhalation and intratracheal instillation studies , 2011, Inhalation toxicology.

[21]  A. Bucht,et al.  Lung exposure of titanium dioxide nanoparticles induces innate immune activation and long-lasting lymphocyte response in the Dark Agouti rat , 2011, Journal of immunotoxicology.

[22]  Maria Hammer,et al.  Time-response relationship of nano and micro particle induced lung inflammation. Quartz as reference compound , 2010, Human & experimental toxicology.

[23]  Wei-Ning Wang,et al.  Inflammogenic effect of well-characterized fullerenes in inhalation and intratracheal instillation studies , 2010, Particle and Fibre Toxicology.

[24]  A. Moreira,et al.  Pulmonary response after exposure to inhaled nickel hydroxide nanoparticles: Short and long-term studies in mice , 2010, Nanotoxicology.

[25]  P. Biswas,et al.  Concept of Assessing Nanoparticle Hazards Considering Nanoparticle Dosemetric and Chemical/Biological Response Metrics , 2010, Journal of toxicology and environmental health. Part A.

[26]  T. Guilarte,et al.  Silica-Based Nanoparticle Uptake and Cellular Response by Primary Microglia , 2009, Environmental health perspectives.

[27]  Nicklas Raun Jacobsen,et al.  Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice , 2009, Particle and Fibre Toxicology.

[28]  P. Baron,et al.  Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. , 2008, American journal of physiology. Lung cellular and molecular physiology.

[29]  N. Gjerdet,et al.  Induction of cell death by TiO2 nanoparticles: studies on a human monoblastoid cell line. , 2008, Toxicology in vitro : an international journal published in association with BIBRA.

[30]  Manuela Semmler-Behnke,et al.  The role of macrophages in the clearance of inhaled ultrafine titanium dioxide particles. , 2008, American journal of respiratory cell and molecular biology.

[31]  Vincent Castranova,et al.  A biocompatible medium for nanoparticle dispersion , 2008 .

[32]  S. A. Mitsialis,et al.  Heme Oxygenase-1 : A Multifaceted Triple-Threat Molecule The Role of Heme Oxygenase-1 in Pulmonary Disease , 2007 .

[33]  Vicki Stone,et al.  Toxicology of nanoparticles: A historical perspective , 2007 .

[34]  Robert Gelein,et al.  A Comparative Dose-Related Response of Several Key Pro- and Antiinflammatory Mediators in the Lungs of Rats, Mice, and Hamsters After Subchronic Inhalation of Carbon Black , 2006, Journal of occupational and environmental medicine.

[35]  A. Ledbetter,et al.  Comparative pulmonary toxicological assessment of oil combustion particles following inhalation or instillation exposure. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.

[36]  David B Warheit,et al.  Pulmonary instillation studies with nanoscale TiO2 rods and dots in rats: toxicity is not dependent upon particle size and surface area. , 2006, Toxicological sciences : an official journal of the Society of Toxicology.

[37]  T. Xia,et al.  Toxic Potential of Materials at the Nanolevel , 2006, Science.

[38]  J. Finkelstein,et al.  Postnatal Lung Development: Immediate–Early Gene Responses Post Ozone and LPS Exposure , 2006, Inhalation toxicology.

[39]  P. Baron,et al.  Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. , 2005, American journal of physiology. Lung cellular and molecular physiology.

[40]  Wolfgang Kreyling,et al.  Ultrafine Particles Cross Cellular Membranes by Nonphagocytic Mechanisms in Lungs and in Cultured Cells , 2005, Environmental health perspectives.

[41]  G. Oberdörster,et al.  Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles , 2005, Environmental health perspectives.

[42]  Melvin E Andersen,et al.  Dose-dependent transitions in mechanisms of toxicity: case studies. , 2004, Toxicology and applied pharmacology.

[43]  Melvin E Andersen,et al.  Dose-dependent transitions in mechanisms of toxicity. , 2004, Toxicology and applied pharmacology.

[44]  Wolfgang Kreyling,et al.  Electron energy loss spectroscopy for analysis of inhaled ultrafine particles in rat lungs , 2004, Microscopy research and technique.

[45]  J. Everitt,et al.  Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. , 2004, Toxicological sciences : an official journal of the Society of Toxicology.

[46]  W. Kreyling,et al.  Translocation of Inhaled Ultrafine Particles to the Brain , 2004, Inhalation toxicology.

[47]  R. Strieter,et al.  Host innate defenses in the lung: the role of cytokines , 2003, Current opinion in infectious diseases.

[48]  David B Warheit,et al.  Long-term pulmonary responses of three laboratory rodent species to subchronic inhalation of pigmentary titanium dioxide particles. , 2002, Toxicological sciences : an official journal of the Society of Toxicology.

[49]  K. Maemura,et al.  Endotoxin-Induced Mortality Is Related to Increased Oxidative Stress and End-Organ Dysfunction, Not Refractory Hypotension, in Heme Oxygenase-1–Deficient Mice , 2000, Circulation.

[50]  J. Finkelstein,et al.  Pulmonary effects induced by ultrafine PTFE particles. , 2000, Toxicology and applied pharmacology.

[51]  H Salem,et al.  Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: uses and limitations. , 2000, Toxicological sciences : an official journal of the Society of Toxicology.

[52]  J. Finkelstein,et al.  Induction of adaptation to inhaled lipopolysaccharide in young and old rats and mice. , 2000, Inhalation toxicology.

[53]  P. Borm,et al.  Chronic Inflammation and Tumor Formation in Rats After Intratracheal Instillation of High Doses of Coal Dusts, Titanium Dioxides, and Quartz , 2000, Inhalation toxicology.

[54]  B. Asgharian,et al.  A multiple-path model of fiber deposition in the rat lung. , 1998, Toxicological sciences : an official journal of the Society of Toxicology.

[55]  G. Oberdörster,et al.  Intratracheal inhalation vs intratracheal instillation: differences in particle effects. , 1997, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[56]  F. Hirata,et al.  Rat alveolar macrophage cytokine production and regulation of neutrophil recruitment following acute ozone exposure. , 1997, Toxicology and applied pharmacology.

[57]  R. Henderson,et al.  A comparison of the inflammatory response of the lung to inhaled versus instilled particles in F344 rats. , 1995, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[58]  B. Lehnert,et al.  Correlation between particle size, in vivo particle persistence, and lung injury. , 1994, Environmental health perspectives.

[59]  Imre Balásházy,et al.  Particle deposition in airway bifurcations–II. Expiratory flow , 1993 .

[60]  S C Soderholm,et al.  Role of the alveolar macrophage in lung injury: studies with ultrafine particles. , 1992, Environmental health perspectives.

[61]  G. Oberdörster,et al.  Pulmonary retention of ultrafine and fine particles in rats. , 1992, American journal of respiratory cell and molecular biology.

[62]  P. Morrow,et al.  Pulmonary response to toner upon chronic inhalation exposure in rats. , 1991, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[63]  D. Romberger,et al.  Respiratory tract responses to dust: relationships between dust burden, lung injury, alveolar macrophage fibronectin release, and the development of pulmonary fibrosis. , 1990, Toxicology and applied pharmacology.

[64]  G. M. Ridder,et al.  Pulmonary response to silica or titanium dioxide: inflammatory cells, alveolar macrophage-derived cytokines, and histopathology. , 1990, American journal of respiratory cell and molecular biology.

[65]  K. P. Lee,et al.  Pulmonary response to impaired lung clearance in rats following excessive TiO2 dust deposition. , 1986, Environmental research.

[66]  J. Lloyd,et al.  Pinocytosis and phagocytosis: the effect of size of a particulate substrate on its mode of capture by rat peritoneal macrophages cultured in vitro. , 1986, Biochimica et biophysica acta.

[67]  M. Davis,et al.  Pulmonary distribution of particles given by intratracheal instillation or by aerosol inhalation. , 1976, Environmental research.

[68]  É. Vivier,et al.  [Natural killer cells: adaptation and memory in innate immunity]. , 2013, Medecine sciences : M/S.

[69]  V. Hackley,et al.  Measuring the hydrodynamic size of nanoparticles in aqueous media using batch-mode dynamic light scattering. , 2011, Methods in molecular biology.

[70]  Yi Yang,et al.  Distribution Characteristics of nano-TiO2 Aerosol in the Workplace , 2011 .

[71]  John Pendergrass,et al.  Project on Emerging Nanotechnologies , 2007 .

[72]  S. Ryter,et al.  Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models. , 2005, Antioxidants & redox signaling.

[73]  Gianmario Martra,et al.  The surface area rather than the surface coating determines the acute inflammatory response after instillation of fine and ultrafine TiO2 in the rat. , 2002, International journal of hygiene and environmental health.

[74]  A. Churg,et al.  Comparison of the uptake of fine and ultrafine TiO2 in a tracheal explant system. , 1998, American journal of physiology. Lung cellular and molecular physiology.

[75]  C. Cox,et al.  Intratracheal instillation versus intratracheal-inhalation of tracer particles for measuring lung clearance function. , 1997, Experimental lung research.

[76]  Wolfgang Koch,et al.  Chronic Inhalation Exposure of Wistar Rats and two Different Strains of Mice to Diesel Engine Exhaust, Carbon Black, and Titanium Dioxide , 1995 .

[77]  Robert Gelein,et al.  Pulmonary Tissue Access of Ultrafine Particles , 1991 .

[78]  R. Potter,et al.  Glass fiber dissolution in a physiological saline solution , 1991 .

[79]  J. Brain,et al.  Pulmonary deposition: determinants and measurement techniques. , 1991, Toxicologic pathology.

[80]  A. F. Eidson,et al.  Comparative Evaluation of Nose-Only Versus Whole-Body Inhalation Exposures for Rats—Aerosol Characteristics and Lung Deposition , 1990 .

[81]  Günter Oberdörster,et al.  Lung Clearance of Inhaled Insoluble and Soluble Particles , 1988 .