Differential regulation of the Sir2 histone deacetylase gene family by inhibitors of class I and II histone deacetylases

[1]  J. Denu,et al.  The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. , 2003, Molecular cell.

[2]  D. O’Carroll,et al.  Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression , 2002, The EMBO journal.

[3]  J. Denu,et al.  Structural Identification of 2′- and 3′-O-Acetyl-ADP-ribose as Novel Metabolites Derived from the Sir2 Family of β-NAD+-dependent Histone/Protein Deacetylases* 210 , 2002, The Journal of Biological Chemistry.

[4]  Ricky W. Johnstone,et al.  Histone-deacetylase inhibitors: novel drugs for the treatment of cancer , 2002, Nature Reviews Drug Discovery.

[5]  J. Boeke,et al.  Chemistry of gene silencing: the mechanism of NAD+-dependent deacetylation reactions. , 2001, Biochemistry.

[6]  D. Gottschling,et al.  Identification of a small molecule inhibitor of Sir2p , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[7]  S. Gasser,et al.  The molecular biology of the SIR proteins. , 2001, Gene.

[8]  V. Richon,et al.  Histone deacetylase inhibitors as new cancer drugs , 2001, Current opinion in oncology.

[9]  S. Schreiber,et al.  Identification of a Class of Small Molecule Inhibitors of the Sirtuin Family of NAD-dependent Deacetylases by Phenotypic Screening* , 2001, The Journal of Biological Chemistry.

[10]  Delin Chen,et al.  Negative Control of p53 by Sir2α Promotes Cell Survival under Stress , 2001, Cell.

[11]  R. Weinberg,et al.  hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase , 2001, Cell.

[12]  M. Jung,et al.  Inhibitors of histone deacetylase as new anticancer agents. , 2001, Current medicinal chemistry.

[13]  R. Sternglanz,et al.  Crystal Structure of a SIR2 Homolog–NAD Complex , 2001, Cell.

[14]  L. Pillus,et al.  Deciphering NAD-Dependent Deacetylases , 2001, Cell.

[15]  A. Verdel,et al.  Functional significance of histone deacetylase diversity. , 2001, Current opinion in genetics & development.

[16]  T. Ekström,et al.  The human histone deacetylase family. , 2001, Experimental cell research.

[17]  D. Shore The Sir2 protein family: A novel deacetylase for gene silencing and more. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[18]  S. Schreiber,et al.  Genomewide studies of histone deacetylase function in yeast. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[19]  P. Marks,et al.  Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells. , 2000, Journal of the National Cancer Institute.

[20]  R. Frye,et al.  Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. , 2000, Biochemical and biophysical research communications.

[21]  T. Suuronen,et al.  Protective effect of L-deprenyl against apoptosis induced by okadaic acid in cultured neuronal cells. , 2000, Biochemical pharmacology.

[22]  L. Guarente,et al.  Sir2 links chromatin silencing, metabolism, and aging. , 2000, Genes & development.

[23]  J. Antonini,et al.  Superinduction of CYP1A1 Gene Expression , 2000, The Journal of Biological Chemistry.

[24]  D. Ayer,et al.  Histone deacetylases: transcriptional repression with SINers and NuRDs. , 1999, Trends in cell biology.

[25]  T. Suuronen,et al.  Neuronal apoptosis induced by histone deacetylase inhibitors. , 1998, Brain research. Molecular brain research.

[26]  A. Razin,et al.  CpG methylation, chromatin structure and gene silencing—a three‐way connection , 1998, The EMBO journal.

[27]  S. Gullans,et al.  Differential expression of human histone deacetylase mRNAs in response to immune cell apoptosis induction by trichostatin A and butyrate. , 1998, Biochemical and biophysical research communications.

[28]  S. Horinouchi,et al.  Trichostatin A and trapoxin: Novel chemical probes for the role of histone acetylation in chromatin structure and function , 1995, BioEssays : news and reviews in molecular, cellular and developmental biology.

[29]  G. Brewer,et al.  Optimized survival of hippocampal neurons in B27‐supplemented neurobasal™, a new serum‐free medium combination , 1993, Journal of neuroscience research.

[30]  G. Church,et al.  Genomic sequencing. , 1993, Methods in molecular biology.

[31]  Stuart L Schreiber,et al.  Deacetylase enzymes: biological functions and the use of small-molecule inhibitors. , 2002, Chemistry & biology.

[32]  N. Pavletich,et al.  Structure of the histone deacetylase SIRT2 , 2001, Nature Structural Biology.

[33]  Q. Ma,et al.  Superinduction of CYP 1 A 1 Gene Expression REGULATION OF 2 , 3 , 7 , 8 - , 2000 .