Role of the faecal immunochemical test in patients with risk-stratified suspected colorectal cancer symptoms: A systematic review and meta-analysis to inform the ACPGBI/BSG guidelines

[1]  M. Abulafi,et al.  The state of the faecal immunochemical test in symptomatic patients in the UK. , 2022, Annals of the Royal College of Surgeons of England.

[2]  L. Schwettmann,et al.  Evaluation of the Sentinel-FOB gold faecal immunochemical test for the presence of haemoglobin using the automated Roche Cobas 8000 system , 2022, Practical laboratory medicine.

[3]  A. Hackshaw,et al.  Faecal immunochemical test for patients with ‘high-risk’ bowel symptoms: a large prospective cohort study and updated literature review , 2021, British Journal of Cancer.

[4]  T. Rockall,et al.  Diagnostic accuracy of point of care faecal immunochemical testing using a portable high‐speed quantitative analyser for diagnosis in 2‐week wait patients , 2021, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[5]  J. Cubiella,et al.  Faecal immunochemical tests safely enhance rational use of resources during the assessment of suspected symptomatic colorectal cancer in primary care: systematic review and meta-analysis , 2021, Gut.

[6]  J. Turvill,et al.  The Fast Track FIT study: diagnostic accuracy of faecal immunochemical test for haemoglobin in patients with suspected colorectal cancer , 2021, The British journal of general practice : the journal of the Royal College of General Practitioners.

[7]  P. Ziprin,et al.  Faecal immunochemical testing in symptomatic patients to prioritize investigation: diagnostic accuracy from NICE FIT Study. , 2021, The British journal of surgery.

[8]  D. Humes,et al.  Faecal immunochemical testing and blood tests for prioritization of urgent colorectal cancer referrals in symptomatic patients: a 2-year evaluation , 2021, BJS open.

[9]  M. Abulafi,et al.  Using the faecal immunochemical test in patients with rectal bleeding: evidence from the NICE FIT study , 2021, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[10]  R. Byford,et al.  Diagnostic performance of a faecal immunochemical test for patients with low-risk symptoms of colorectal cancer in primary care: an evaluation in the South West of England , 2021, British Journal of Cancer.

[11]  C. Mowat,et al.  Faecal haemoglobin concentration thresholds for reassurance and urgent investigation for colorectal cancer based on a faecal immunochemical test in symptomatic patients in primary care , 2020, Annals of clinical biochemistry.

[12]  D. Humes,et al.  Choice of faecal immunochemical test matters: comparison of OC-Sensor and HM-JACKarc, in the assessment of patients at high risk of colorectal cancer , 2020, Clinical chemistry and laboratory medicine.

[13]  C. Mowat,et al.  Yield of colorectal cancer at colonoscopy according to faecal haemoglobin concentration in symptomatic patients referred from primary care , 2020, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[14]  M. Abulafi,et al.  Faecal immunochemical test is superior to symptoms in predicting pathology in patients with suspected colorectal cancer symptoms referred on a 2WW pathway: a diagnostic accuracy study , 2020, Gut.

[15]  A. A. Khan,et al.  Accuracy of faecal immunochemical testing in patients with symptomatic colorectal cancer , 2020, BJS open.

[16]  Á. Lanas,et al.  Reducing the Cut-Off Value of the Fecal Immunochemical Test for Symptomatic Patients Does Not Improve Diagnostic Performance , 2020, Frontiers in Medicine.

[17]  J. Cubiella,et al.  Optimal diagnostic accuracy of quantitative faecal immunochemical test positivity thresholds for colorectal cancer detection in primary health care: A community‐based cohort study , 2020, United European gastroenterology journal.

[18]  B. Nicholson,et al.  Faecal immunochemical testing for adults with symptoms of colorectal cancer attending English primary care: a retrospective cohort study of 14 487 consecutive test requests , 2020, Alimentary pharmacology & therapeutics.

[19]  C. Mowat,et al.  ANNALS EXPRESS: Measurement of faecal haemoglobin with a faecal immunochemical test (FIT) can assist in defining which patients attending primary care with rectal bleeding require urgent referral. , 2020, Annals of clinical biochemistry.

[20]  R. Harshen,et al.  FIT negative cancers: A right-sided problem? Implications for screening and whether iron deficiency anaemia has a role to play. , 2020, The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland.

[21]  T. Rockall,et al.  The two-week rule colorectal cancer pathway: an update on recent practice, the unsustainable burden on diagnostics and the role of faecal immunochemical testing. , 2020, Annals of the Royal College of Surgeons of England.

[22]  P. Hellström,et al.  Diagnostic accuracy of a quantitative faecal immunochemical test vs. symptoms suspected for colorectal cancer in patients referred for colonoscopy , 2020, Scandinavian journal of gastroenterology.

[23]  M. Abulafi,et al.  The diagnostic accuracy of the faecal immunochemical test for colorectal cancer in risk-stratified symptomatic patients. , 2019, Annals of the Royal College of Surgeons of England.

[24]  J. Cubiella,et al.  High-risk symptoms and quantitative faecal immunochemical test accuracy: Systematic review and meta-analysis , 2019, World journal of gastroenterology.

[25]  R. Arasaradnam,et al.  Faecal immunochemical testing (FIT) in symptomatic patients: what are we missing? , 2019, Frontline Gastroenterology.

[26]  F. Cotter,et al.  Potential roles of artificial intelligence learning and faecal immunochemical testing for prioritisation of colonoscopy in anaemia , 2019, British journal of haematology.

[27]  J. Søndergaard,et al.  Predictive values of colorectal cancer alarm symptoms in the general population: a nationwide cohort study , 2019, British Journal of Cancer.

[28]  J. Cubiella,et al.  Symptom or faecal immunochemical test based referral criteria for colorectal cancer detection in symptomatic patients: a diagnostic tests study , 2018, BMC Gastroenterology.

[29]  B. Nicholson,et al.  Experience of adopting faecal immunochemical testing to meet the NICE colorectal cancer referral criteria for low-risk symptomatic primary care patients in Oxfordshire, UK , 2018, Frontline Gastroenterology.

[30]  S. Laurberg,et al.  The value of using the faecal immunochemical test in general practice on patients presenting with non-alarm symptoms of colorectal cancer , 2018, British Journal of Cancer.

[31]  S. Thomas-Gibson,et al.  Endoscopy in 2017: a national survey of practice in the UK , 2018, Frontline Gastroenterology.

[32]  J. Kleijnen,et al.  Faecal immunochemical tests (FIT) can help to rule out colorectal cancer in patients presenting in primary care with lower abdominal symptoms: a systematic review conducted to inform new NICE DG30 diagnostic guidance , 2017, BMC Medicine.

[33]  S. Smith,et al.  Diagnostic accuracy of faecal biomarkers in detecting colorectal cancer and adenoma in symptomatic patients , 2017, Alimentary pharmacology & therapeutics.

[34]  C. Fraser,et al.  Use of a faecal immunochemical test for haemoglobin can aid in the investigation of patients with lower abdominal symptoms , 2016, Clinical chemistry and laboratory medicine.

[35]  V. Moreno,et al.  An urgent referral strategy for symptomatic patients with suspected colorectal cancer based on a quantitative immunochemical faecal occult blood test. , 2015, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.

[36]  C. Mowat,et al.  Faecal haemoglobin and faecal calprotectin as indicators of bowel disease in patients presenting to primary care with bowel symptoms , 2015, Gut.

[37]  Susan Mallett,et al.  QUADAS-2: A Revised Tool for the Quality Assessment of Diagnostic Accuracy Studies , 2011, Annals of Internal Medicine.

[38]  Steve Halligan,et al.  Colorectal cancer: CT colonography and colonoscopy for detection--systematic review and meta-analysis. , 2011, Radiology.

[39]  Johannes B Reitsma,et al.  Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. , 2005, Journal of clinical epidemiology.

[40]  Jonathan J Deeks,et al.  The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed. , 2005, Journal of clinical epidemiology.

[41]  Johannes B Reitsma,et al.  Case-control and two-gate designs in diagnostic accuracy studies. , 2005, Clinical chemistry.

[42]  P. Bossuyt,et al.  Sources of Variation and Bias in Studies of Diagnostic Accuracy , 2004, Annals of Internal Medicine.

[43]  P. Bossuyt,et al.  Empirical evidence of design-related bias in studies of diagnostic tests. , 1999, JAMA.

[44]  OUP accepted manuscript , 2021, British Journal of Surgery.

[45]  M. Cowie.  National Institute for Health and Care Excellence. , 2015, European heart journal.