Titanium versus polyetheretherketone implants for vertebral body replacement in the treatment of 77 thoracolumbar spinal fractures

Background: Titanium and polyetheretherketone (PEEK) implants have been used in spinal surgery with low rejection rates. Compared to titanium, PEEK has many advantages, including a density more similar to that of bone, radiolucency, and a lack of artifacts in computed tomography (CT) and magnetic resonance imaging (MRI). In this study, we evaluated the effectiveness of PEEK cages as an alternative to titanium for bone fusion after fractures of the thoracolumbar spine. We also propose a classification to the impaction index. Methods: We evaluated 77 patients with fractures of the thoracic or lumbar spine who were treated by anterior fixation with titanium cages (TeCorp®) in 46 (59.7%) patients or PEEK (Verte-stak®) in 31 (40.3%) patients from 2006 to 2012 (Neurological Hospital of Lyon). Results: The titanium group achieved 100% fusion, and the PEEK group achieved 96.3% fusion. The titanium systems correlated with higher impact stress directed toward the lower and upper plateaus of the fused vertebrae; there were no nonunions for those treated with titanium group. Nevertheless, there was only one in the PEEK group. There was no significant difference in the pain scale outcomes for patients with ±10 degrees of the sagittal angle. Statistically, it is not possible to associate the variation of sagittal alignment or the impaction with symptoms of pain. The complication rate related to the implantation of cages was low. Conclusions: Titanium and PEEK are thus equally effective options for the reconstruction of the anterior column. PEEK is advantageous because its radiolucency facilitates the visualization of bone bridges.

[1]  Ping Liu,et al.  Analysis of surgical approaches for unstable thoracolumbar burst fracture: minimum of five year follow-up. , 2015, JPMA. The Journal of the Pakistan Medical Association.

[2]  H. Dufour,et al.  Circumferential management of unstable thoracolumbar fractures using an anterior expandable cage, as an alternative to an iliac crest graft, combined with a posterior screw fixation: results of a series of 85 patients. , 2014, Neurosurgical focus.

[3]  F. Kandziora,et al.  Five-year clinical and radiological results of combined anteroposterior stabilization of thoracolumbar fractures. , 2014, Journal of neurosurgery. Spine.

[4]  C. Niu,et al.  Outcomes of Interbody Fusion Cages Used in 1 and 2-levels Anterior Cervical Discectomy and Fusion: Titanium Cages Versus Polyetheretherketone (PEEK) Cages , 2010, Journal of spinal disorders & techniques.

[5]  S. Aunoble,et al.  Video-assisted treatment of thoracolumbar junction fractures using a specific distractor for reduction: prospective study of 50 cases , 2010, European Spine Journal.

[6]  M. Aebi,et al.  A comprehensive classification of thoracic and lumbar injuries , 2005, European Spine Journal.

[7]  H. Schroeder,et al.  Limitations of dorsal transpedicular stabilization in unstable fractures of the lower thoracic and lumbar spine: an analysis of 133 patients , 2004, Acta Neurochirurgica.

[8]  W. Dhert,et al.  Surgical Treatment of Traumatic Fractures of the Thoracic and Lumbar Spine: A Systematic Review of the Literature on Techniques, Complications, and Outcome , 2004, Spine.

[9]  Daniel H. Kim,et al.  Vertebral body replacement with an expandable cage for reconstruction after spinal tumor resection. , 2003, Neurosurgical focus.

[10]  C. Fisher,et al.  Effectiveness of Titanium Mesh Cylindrical Cages in Anterior Column Reconstruction After Thoracic and Lumbar Vertebral Body Resection , 2003, Spine.

[11]  K. Wood,et al.  Operative compared with nonoperative treatment of a thoracolumbar burst fracture without neurological deficit. A prospective, randomized study. , 2003 .

[12]  A. Alanay,et al.  Short-Segment Pedicle Instrumentation of Thoracolumbar Burst Fractures: Does Transpedicular Intracorporeal Grafting Prevent Early Failure? , 2001, Spine.

[13]  Marc A. Asher,et al.  Iliac Crest Bone Graft Harvest Donor Site Morbidity: A Statistical Evaluation , 1995, Spine.

[14]  J. Dubousset Early failure of short-segment pedicle instrumentation for thoracolumbar fractures. A preliminary report. , 1995, The Journal of bone and joint surgery. American volume.

[15]  J. Meding,et al.  Critical analysis of strut grafts in anterior spinal fusions. , 1993, Journal of spinal disorders.

[16]  R E Booth,et al.  Harvesting Autogenous Iliac Bone Grafts: A Review of Complications and Techniques , 1989, Spine.

[17]  J. Cotler,et al.  The Use of Autografts for Vertebral Body Replacement of the Thoracic and Lumbar Spine , 1985, Spine.