2-Aminoindan and its ring-substituted derivatives interact with plasma membrane monoamine transporters and α2-adrenergic receptors
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[1] J. Shimshoni,et al. Pharmacokinetic and pharmacodynamic evaluation of 5‐methoxy‐2‐aminoindane (MEAI): A new binge‐mitigating agent , 2018, Toxicology and applied pharmacology.
[2] M. Mameli,et al. Positive regulation of raphe serotonin neurons by serotonin 2B receptors , 2018, Neuropsychopharmacology.
[3] M. Huestis,et al. Impact of Novel Psychoactive Substances on Clinical and Forensic Toxicology and Global Public Health. , 2017, Clinical chemistry.
[4] M. Freissmuth,et al. Conformational state interactions provide clues to the pharmacochaperone potential of serotonin transporter partial substrates , 2017, The Journal of Biological Chemistry.
[5] S. Krähenbühl,et al. Pharmacological profile of mephedrone analogs and related new psychoactive substances , 2017, Neuropharmacology.
[6] A. Atkinson,et al. Online test purchased new psychoactive substances in 5 different European countries: A snapshot study of chemical composition and price. , 2017, The International journal on drug policy.
[7] R. Glennon,et al. N-Alkylated Analogs of 4-Methylamphetamine (4-MA) Differentially Affect Monoamine Transporters and Abuse Liability , 2017, Neuropsychopharmacology.
[8] D. Nutt,et al. Toxicological evaluation of 5‐methoxy‐2‐aminoindane (MEAI): Binge mitigating agent in development , 2017, Toxicology and applied pharmacology.
[9] A. Janowsky,et al. Structure-Activity Relationships of Substituted Cathinones, with Transporter Binding, Uptake, and Release , 2017, The Journal of Pharmacology and Experimental Therapeutics.
[10] M. Forster,et al. Locomotor, discriminative stimulus, and place conditioning effects of MDAI in rodents , 2016, Behavioural pharmacology.
[11] Kurt R. Lehner,et al. Reinforcing and neurochemical effects of the “bath salts” constituents 3,4-methylenedioxypyrovalerone (MDPV) and 3,4-methylenedioxy-N-methylcathinone (methylone) in male rats , 2016, Psychopharmacology.
[12] R. Freyberg,et al. Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain , 2016, Nature Communications.
[13] R. Glennon,et al. Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats , 2016, European Neuropsychopharmacology.
[14] N. Volkow,et al. Abuse of New Psychoactive Substances: Threats and Solutions , 2016, Neuropsychopharmacology.
[15] H. Sitte,et al. Binding Mode Selection Determines the Action of Ecstasy Homologs at Monoamine Transporters , 2016, Molecular Pharmacology.
[16] T. Paunio,et al. Impulsive alcohol-related risk-behavior and emotional dysregulation among individuals with a serotonin 2B receptor stop codon , 2015, Translational Psychiatry.
[17] R. Niesink,et al. 4-Fluoroamphetamine in the Netherlands: more than a one-night stand. , 2015, Addiction.
[18] M. Slezak. A not-so-bitter pill , 2015 .
[19] H. Sitte,et al. Amphetamines, new psychoactive drugs and the monoamine transporter cycle , 2014, Trends in pharmacological sciences.
[20] S. Elliott,et al. A 3-year review of new psychoactive substances in casework. , 2014, Forensic science international.
[21] Michael Krauss,et al. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins , 2014, Science.
[22] M. Liechti,et al. Monoamine transporter and receptor interaction profiles of a new series of designer cathinones , 2014, Neuropharmacology.
[23] M. Liechti,et al. Pharmacological profiles of aminoindanes, piperazines, and pipradrol derivatives. , 2014, Biochemical pharmacology.
[24] O. Corazza,et al. MDAI (5,6‐methylenedioxy‐2‐aminoindane; 6,7‐dihydro‐5H‐cyclopenta[f][1,3]benzodioxol‐6‐amine; ‘sparkle’; ‘mindy’) toxicity: a brief overview and update , 2013, Human psychopharmacology.
[25] Kurt R. Lehner,et al. Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products , 2013, Neuropsychopharmacology.
[26] S. Negus,et al. Use of intracranial self‐stimulation to evaluate abuse‐related and abuse‐limiting effects of monoamine releasers in rats , 2013, British journal of pharmacology.
[27] V. Setola,et al. Neurochemical profiles of some novel psychoactive substances. , 2013, European journal of pharmacology.
[28] H. Sitte,et al. Pharmacological examination of trifluoromethyl ring-substituted methcathinone analogs. , 2013, European journal of pharmacology.
[29] M. Liechti,et al. Pharmacological characterization of designer cathinones in vitro , 2013, British journal of pharmacology.
[30] Maria F. Sassano,et al. Automated design of ligands to polypharmacological profiles , 2012, Nature.
[31] R. Rothman,et al. The Designer Methcathinone Analogs, Mephedrone and Methylone, are Substrates for Monoamine Transporters in Brain Tissue , 2012, Neuropsychopharmacology.
[32] S. Johansen,et al. Isomers of fluoroamphetamines detected in forensic cases in Denmark , 2012, International Journal of Legal Medicine.
[33] M. Liechti,et al. The Norepinephrine Transporter Inhibitor Reboxetine Reduces Stimulant Effects of MDMA (“Ecstasy”) in Humans , 2011, Clinical pharmacology and therapeutics.
[34] B. Blough,et al. In Vivo Effects of Amphetamine Analogs Reveal Evidence for Serotonergic Inhibition of Mesolimbic Dopamine Transmission in the Rat , 2011, Journal of Pharmacology and Experimental Therapeutics.
[35] R. Depoortère,et al. The central serotonin2B receptor: a new pharmacological target to modulate the mesoaccumbens dopaminergic pathway activity , 2010, Journal of neurochemistry.
[36] I. Kirk,et al. Determining the subjective effects of TFMPP in human males , 2010, Psychopharmacology.
[37] T. Kosten,et al. Atomoxetine Attenuates Dextroamphetamine Effects in Humans , 2009, The American journal of drug and alcohol abuse.
[38] D. Hervé,et al. Role of Serotonin via 5-HT2B Receptors in the Reinforcing Effects of MDMA in Mice , 2009, PloS one.
[39] Bryan L. Roth,et al. Parallel Functional Activity Profiling Reveals Valvulopathogens Are Potent 5-Hydroxytryptamine2B Receptor Agonists: Implications for Drug Safety Assessment , 2009, Molecular Pharmacology.
[40] S. Shepherd. A not so bitter pill. , 2009, The Health service journal.
[41] M. Forster,et al. Comparison of the discriminative stimulus effects of dimethyltryptamine with different classes of psychoactive compounds in rats , 2009, Psychopharmacology.
[42] V. Setola,et al. Serotonin 5-HT2B Receptors Are Required for 3,4-Methylenedioxymethamphetamine-Induced Hyperlocomotion and 5-HT Release In Vivo and In Vitro , 2008, The Journal of Neuroscience.
[43] J. Javitch,et al. Currents in Response to Rapid Concentration Jumps of Amphetamine Uncover Novel Aspects of Human Dopamine Transporter Function , 2008, The Journal of Neuroscience.
[44] R. de la Torre,et al. Pharmacological Interaction between 3,4-Methylenedioxymethamphetamine (Ecstasy) and Paroxetine: Pharmacological Effects and Pharmacokinetics , 2007, Journal of Pharmacology and Experimental Therapeutics.
[45] P. Franken,et al. Possible association between 3,4-methylenedioxymethamphetamine abuse and valvular heart disease. , 2007, The American journal of cardiology.
[46] F. Nagai,et al. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. , 2007, European journal of pharmacology.
[47] B. Roth. Drugs and valvular heart disease. , 2007, The New England journal of medicine.
[48] R. C. Pierce,et al. The mesolimbic dopamine system: The final common pathway for the reinforcing effect of drugs of abuse? , 2006, Neuroscience & Biobehavioral Reviews.
[49] M. Tancer,et al. The effects of fluoxetine on the subjective and physiological effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans , 2006, Psychopharmacology.
[50] Allison G. Dempsey,et al. Interaction of Amphetamines and Related Compounds at the Vesicular Monoamine Transporter , 2006, Journal of Pharmacology and Experimental Therapeutics.
[51] R. Rothman,et al. Therapeutic potential of monoamine transporter substrates. , 2006, Current topics in medicinal chemistry.
[52] R. Rothman,et al. Balance between Dopamine and Serotonin Release Modulates Behavioral Effects of Amphetamine‐Type Drugs , 2006, Annals of the New York Academy of Sciences.
[53] K G Anderson,et al. Relationship between the Serotonergic Activity and Reinforcing Effects of a Series of Amphetamine Analogs , 2005, Journal of Pharmacology and Experimental Therapeutics.
[54] D. Sulzer,et al. Mechanisms of neurotransmitter release by amphetamines: A review , 2005, Progress in Neurobiology.
[55] B. Blough,et al. N-Substituted Piperazines Abused by Humans Mimic the Molecular Mechanism of 3,4-Methylenedioxymethamphetamine (MDMA, or ‘Ecstasy’) , 2005, Neuropsychopharmacology.
[56] G. Uhl,et al. The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuse. , 2004, Pharmacogenetics.
[57] V. Setola,et al. 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro. , 2003, Molecular pharmacology.
[58] Michael H. Baumann,et al. (+)-Fenfluramine and Its Major Metabolite, (+)-Norfenfluramine, Are Potent Substrates for Norepinephrine Transporters , 2003, Journal of Pharmacology and Experimental Therapeutics.
[59] M. Humbert,et al. Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension , 2002, Nature Medicine.
[60] B. Roth,et al. Evidence for Possible Involvement of 5-HT2B Receptors in the Cardiac Valvulopathy Associated With Fenfluramine and Other Serotonergic Medications , 2000, Circulation.
[61] H. Palevsky,et al. Recreational use of aminorex and pulmonary hypertension. , 2000, Chest.
[62] F. Vollenweider,et al. Acute Psychological Effects of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) are Attenuated by the Serotonin Uptake Inhibitor Citalopram , 1999, Neuropsychopharmacology.
[63] R. Rothman,et al. Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. , 1999, Circulation.
[64] D. Marona-Lewicka,et al. Drug discrimination studies of the interoceptive cues produced by selective serotonin uptake inhibitors and selective serotonin releasing agents , 1998, Psychopharmacology.
[65] E. Pothos,et al. Vesicular Transport Regulates Monoamine Storage and Release but Is Not Essential for Amphetamine Action , 1997, Neuron.
[66] R. Wise,et al. The neurobiology of addiction , 2019, Annals of the New York Academy of Sciences.
[67] D. Marona-Lewicka,et al. Reinforcing effects of certain serotonin-releasing amphetamine derivatives , 1996, Pharmacology Biochemistry and Behavior.
[68] D. Sulzer,et al. Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[69] D. Marona-Lewicka,et al. Behavioral effects of the highly selective serotonin releasing agent 5-methoxy-6-methyl-2-aminoindan. , 1994, European journal of pharmacology.
[70] G. Rudnick,et al. From synapse to vesicle: the reuptake and storage of biogenic amine neurotransmitters. , 1993, Biochimica et biophysica acta.
[71] M. P. Johnson,et al. [3H]monoamine releasing and uptake inhibition properties of 3,4-methylenedioxymethamphetamine and p-chloroamphetamine analogues. , 1991, European journal of pharmacology.
[72] M W Fischman,et al. Assessment of abuse liability of stimulant drugs in humans: a methodological survey. , 1991, Drug and alcohol dependence.
[73] M. P. Johnson,et al. Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA). , 1991, Journal of medicinal chemistry.
[74] R. Oberlender,et al. Structural variation and (+)-amphetamine-like discriminative stimulus properties , 1991, Pharmacology Biochemistry and Behavior.
[75] L. D. Reid,et al. Methylenedioxymethamphetamine's capacity to establish place preferences and modify intake of an alcoholic beverage , 1990, Pharmacology Biochemistry and Behavior.
[76] R. Oberlender,et al. (+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine as a discriminative stimulus in studies of 3,4-methylenedioxy-methamphetamine-like behavioral activity. , 1990, The Journal of pharmacology and experimental therapeutics.
[77] R. M. Riggs,et al. Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA). , 1990, Journal of medicinal chemistry.
[78] E. D. De Souza,et al. Pharmacologic profile of MDMA (3,4-methylenedioxymethamphetamine) at various brain recognition sites. , 1988, European journal of pharmacology.
[79] M. D. Schechter. Discriminative profile of MDMA , 1986, Pharmacology Biochemistry and Behavior.
[80] R. Glennon,et al. Structure-activity studies on amphetamine analogs using drug discrimination methodology , 1984, Pharmacology Biochemistry and Behavior.
[81] J. Nutt,et al. A comparison of fenfluramine and amphetamine in man , 1975, Clinical pharmacology and therapeutics.
[82] Y. Cheng,et al. Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. , 1973, Biochemical pharmacology.
[83] A. Halberstadt. Pharmacology and Toxicology of N-Benzylphenethylamine ("NBOMe") Hallucinogens. , 2017, Current topics in behavioral neurosciences.
[84] R. Braithwaite,et al. Chapter 11 – Aminoindane Analogues , 2013 .
[85] K. Rice,et al. Amphetamine‐type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin , 2001, Synapse.
[86] B. Largent,et al. Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine. , 2000, Molecular pharmacology.
[87] L. Pallanck,et al. Mechanisms of neurotransmitter release. , 1999, International review of neurobiology.
[88] Glennon Ra. Stimulus properties of hallucinogenic phenalkylamines and related designer drugs: formulation of structure-activity relationships. , 1989 .
[89] R. Glennon. Stimulus properties of hallucinogenic phenalkylamines and related designer drugs: formulation of structure-activity relationships. , 1989, NIDA research monograph.
[90] V. P. Whittaker,et al. The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. , 1962, Journal of anatomy.
[91] Hans-Peter Benedikt. VII. Das β‐Hydrindon und einige seiner Derivate , 1893 .