ECOLOGICAL INTERACTION OF WILDLIFE, MAN, AND A VIRUS OF THE VENEZUELAN EQUINE ENCEPHALOMYELITIS COMPLEX IN A TROPICAL FOREST

Venezuelan equine encephalomyelitis (VE) virus was isolated 18 times from blood of Oryzomys in tropical forests near Belem, Brazil. Rainfall, Culex population levels, and nonimmune Oryzomys population levels were analyzed during 1962 to 1964 and 1968 to 1970 for association with transmission of VE virus. A positive correlation between VE virus transmission in Oryzomys and the abundance of nonimmune animals was determined. Infection of man with rodent-associated viruses such as VE probably occurs during crepuscular hours when Culex (Melanoconion) mosquitoes and rodents are active.