Synthesis of Some 3‐Substituted Isochromen‐1‐ones

Abstract An alternative method for the synthesis of 3‐substituted isocoumarins from homophthalic acid and ester is described.

[1]  Yoshinori Yamamoto,et al.  Microwave-enhanced Pd(0)/acetic acid catalyzed allylation reactions of C, N, and O-pronucleophiles with alkynes , 2004 .

[2]  F. Khan,et al.  Electrocatalytic oxidative cleavage by electrogenerated periodate , 2003 .

[3]  F. Khan,et al.  Electrochemical reductive allylation of N-benzylideneethanolamine , 2002 .

[4]  J. J. Lee,et al.  Anti-angiogenic activities of novel isocoumarins, AGI-7 and sescandelin. , 2001, The Journal of antibiotics.

[5]  D. Mal,et al.  Total synthesis of coriandrin and 7-demethylcoriandrin via a new synthesis of isocoumarins , 2000 .

[6]  R. Rossi,et al.  Regioselective Synthesis of Natural and Unnatural (Z)-3-(1-Alkylidene)phthalides and 3-Substituted Isocoumarins Starting from Methyl 2-Hydroxybenzoates , 2000 .

[7]  R. Bernini,et al.  Oxidation of 3-arylisochromans by dimethyldioxirane. An easy route to substituted 3-arylisocoumarins , 1999 .

[8]  R. Larock,et al.  Synthesis of Isocoumarins and alpha-Pyrones via Palladium-Catalyzed Annulation of Internal Alkynes. , 1999, The Journal of organic chemistry.

[9]  H. Sashida,et al.  Palladium-Catalyzed Intramolecular Cyclization of o-Ethynylbenzoic Acids and o-Ethynylbenzamides: Preparation of Isocoumarins and Isoquinolin-1-ones , 1999 .

[10]  H. Shimoda,et al.  Structure-requirements of isocoumarins, phthalides, and stilbenes from Hydrangeae Dulcis Folium for inhibitory activity on histamine release from rat peritoneal mast cells. , 1999, Bioorganic & medicinal chemistry.

[11]  Le Wang,et al.  Synthesis of isocoumarins via palladium catalyzed reactions of methyl 2-(2′, 2′-dibromovinyl)benzoates , 1998 .

[12]  Abdullah F U H Saeed,et al.  Synthesis of Antibacterial Isocoumarins: Synthesis and Antibacterial Activity of 3‐Alkylisocoumarins and (dl)‐3‐Alkyl‐3,4‐dihydroisocoumarins. , 1998 .

[13]  H. Shimoda,et al.  Development of bioactive functions in Hydrangeae Dulcis Folium. VII. Immunomodulatory activities of thunberginol A and related compounds on lymphocyte proliferation. , 1998, Biological & pharmaceutical bulletin.

[14]  K. N. Babu,et al.  Reactions of 3-(1-Hydroxyalkyl)phthalides with Acids: Synthesis of (Z)-3-Alkylidenephthalides and 3-Alkyl-8-hydroxyisocoumarins. , 1998, The Journal of organic chemistry.

[15]  H. Shimoda,et al.  Immunomodulatory activity of thunberginol A and related compounds isolated from Hydrangeae Dulcis Folium on splenocyte proliferation activated by mitogens. , 1998, Bioorganic & medicinal chemistry letters.

[16]  E. Napolitano THE SYNTHESIS OF ISOCOUMARINS OVER THE LAST DECADE. A REVIEW , 1997 .

[17]  H. Shimoda,et al.  Development of bioactive functions in Hydrangeae dulcis folium. VI. Syntheses of thunberginols A and F and their 3'-deoxy-derivatives using regiospecific lactonization of stilbene carboxylic acid: structures and inhibitory activity on histamine release of hydramacrophyllols A and B. , 1996, Chemical & pharmaceutical bulletin.

[18]  J. Scott,et al.  Cercophorins A-C: novel antifungal and cytotoxic metabolites from the coprophilous fungus Cercophora areolata. , 1996, Journal of natural products.

[19]  T. Doi,et al.  Novel, potent, and orally active substance P antagonists: synthesis and antagonist activity of N-benzylcarboxamide derivatives of pyrido[3,4-b]pyridine. , 1995, Journal of medicinal chemistry.

[20]  Chien‐Hong Cheng,et al.  SYNTHESIS OF ISOCOUMARINS FROM O-IODOBENZOIC ACID AND TERMINAL ACETYLENES MEDIATED BY PALLADIUM COMPLEXES AND ZINC CHLORIDE , 1995 .

[21]  Yumio Nakamura,et al.  SYNTHESIS OF 3-SUBSTITUTED ISOCOUMARINS THROUGH ACYLOXYPALLADATION OF o-ALKENYLBENZOIC ACIDS , 1994 .

[22]  H. Shimoda,et al.  Development of bioactive functions in hydrangeae dulcis folium. III. On the antiallergic and antimicrobial principles of hydrangeae dulcis folium. (1). Thunberginols A, B, and F. , 1994, Chemical & pharmaceutical bulletin.

[23]  H. Aoyama,et al.  CHEMICAL TRANSFORMATION FROM DIHYDROISOCOUMARIN INTO BENZYLIDENEPHTHALIDE BY USE OF REGIOSPECIFIC OXIDATIVE LACTONIZATION MEDIATED BY COPPER CHLORIDE (II) : SYNTHESES OF THUNBERGINOL F AND HYDRAMACROPHYLLOL A AND B , 1994 .

[24]  N. Morishita,et al.  Synthesis of isocoumarin, 1-isoquinolone and 4(1H)-quinolone derivatives via seleno-intermediates , 1994 .

[25]  I. Kawasaki,et al.  Synthesis of 3-substituted isocoumarins and related natural products , 1993 .

[26]  F. Hauser,et al.  A new procedure for regiospecific syntheses of benzopyran-1-ones , 1988 .

[27]  Y. Asakawa,et al.  Polygonolide, an isocoumarin from Polygonum hydropiper possessing anti-inflammatory activity , 1986 .

[28]  S. Nakajima,et al.  Antifungal activity of oosponol, oospolactone, phyllodulcin, hydrangenol, and some other related compounds. , 1981, Chemical & pharmaceutical bulletin.

[29]  F. Zilliken,et al.  Eine neue Synthese von Tetrahydrocapillarin, O-Methylglomellin und Oospolacton , 1980 .

[30]  R. Barry Isocoumarins. Developments Since 1950 , 1964 .

[31]  J. B. Jones,et al.  531. Some synthetical investigations in isocoumarin chemistry , 1958 .