Delta9-tetrahydrocannabinol content of commercially available hemp products.

Delta9-Tetrahydrocannabinol (THC) is the main psychoactive compound present in marijuana. THC can also be found, as a contaminant, in some commercially available hemp products marketed in health food stores and on the internet as a good source of essential fatty acids. The products range from oil to alcoholic beverages to nutritional bars to candies, with oil being the most popular and commonly available. The analytical results are separated into two groups, products tested prior to and after publication of 21 CFR Part 1308, "clarification of listing of tetrahydrocannabinols." The data presented are a summary of 79 different hemp products tested for THC. THC was separated by a liquid-liquid or solid-liquid extraction, depending upon the product matrix. THC concentrations range from none detected to 117.5 microg THC/g material. Typical limits of detection for the assay (depending on matrix) are 1.0-2.5 microg THC/g material. Products that were of aqueous base (beer, tea) had much lower limits of detection (2.5 ng/mL). No THC was detected in 58% of the products from group 1 and 86% of the products from group 2. The amounts indicate that THC levels in currently marketed hemp products are significantly lower than in those products available before 2003 and reported in previous studies. The results reported here may be used as a general guideline for the THC content of hemp products recently found in the marketplace today.

[1]  Richard A. Gustafson,et al.  Urinary cannabinoid detection times after controlled oral administration of delta9-tetrahydrocannabinol to humans. , 2003, Clinical chemistry.

[2]  M. Elsohly Practical challenges to positive drug tests for marijuana. , 2003, Clinical chemistry.

[3]  G. Leson,et al.  Evaluating the impact of hemp food consumption on workplace drug tests. , 2001, Journal of analytical toxicology.

[4]  T. Murphy,et al.  GC-MS analysis of the total delta9-THC content of both drug- and fiber-type cannabis seeds. , 2000, Journal of analytical toxicology.

[5]  T. Bosy,et al.  Consumption and quantitation of delta9-tetrahydrocannabinol in commercially available hemp seed oil products. , 2000, Journal of analytical toxicology.

[6]  C. M. Kunsman,et al.  The effect of consumption of Hempen Ale on urine cannabinoid screens. , 1999, Journal of analytical toxicology.

[7]  R. Brenneisen,et al.  Excretion of cannabinoids in urine after ingestion of cannabis seed oil. , 1997, Journal of analytical toxicology.

[8]  J. Callaway,et al.  A positive THC urinalysis from hemp (Cannabis) seed oil. , 1997, Journal of analytical toxicology.

[9]  P. J. O'Neil,et al.  Survey Variation in the THC Content of Illicitly Imported Cannabis * Products—1984–1989 , 1990, The Journal of pharmacy and pharmacology.

[10]  A. P. Mason,et al.  Cannabis: pharmacology and interpretation of effects. , 1985, Journal of forensic sciences.

[11]  Taylor Bj,et al.  Variation in the THC content in illicitly imported Cannabis products--Part II. , 1982 .

[12]  G. Beduschi,et al.  Delta9 THC content in illicit cannabis products over the period 1997-2004 (first four months). , 2005, Annali dell'Istituto superiore di sanita.

[13]  F. Musshoff,et al.  Determination of cannabinoids in hemp food products by use of headspace solid-phase microextraction and gas chromatography–mass spectrometry , 2004, Analytical and bioanalytical chemistry.

[14]  B. Banahan,et al.  Potency trends of delta9-THC and other cannabinoids in confiscated marijuana from 1980-1997. , 2000, Journal of forensic sciences.

[15]  A. Alt,et al.  Positive cannabis results in urine and blood samples after consumption of hemp food products. , 1998, Journal of analytical toxicology.

[16]  R. Schwartz,et al.  Hemp oil ingestion causes positive urine tests for delta 9-tetrahydrocannabinol carboxylic acid. , 1997, Journal of analytical toxicology.

[17]  Jean-Luc Deferne,et al.  Hemp seed oil: A source of valuable essential fatty acids , 1996 .

[18]  P. B. Baker,et al.  Variation in the THC content in illicitly imported Cannabis products. , 1980, Bulletin on narcotics.