000191 RADICAL PARAMETRECTOMY IN THE TREATMENT OF INVASIVE CERVICAL CANCER AFTER SIMPLE HYSTERECTOMY

To assess the morbidity and efficacy of radical parametrectomy (RP) following simple hysterectomy in patients with invasive cervical carcinoma. Seven year retrospective chart review identified 5 patients that underwent RP with pelvic and paraaortic lymphadenectomy and upper vaginectomy. Data were collected on demographics, tumor stage, histology and survival. One patient had stage IA lesion, one stage IB1, 2patients had stage IIA, and one with unknown stage. One of these patients had adenocarcinoma. Median age was 41.6 years. The most indication for hysterectomy was abnormal vaginal bleeding (3 out of 5, 60%). Two patients had pelvic node metastases. Surgical margins in all 5 patients were tumor free at the time of RP. Two patients with positive pelvic nodes received adjuvant radiotherapy. Mean follow up time was 48.8 months. Four patients are alive without disease, and one patient who had been node positive, died 12 months after receiving radiation. RP is an acceptable option for patients diagnosed with incidental finding of invasive cervical cancer at the time of simple hysterectomy. Careful selection of RP for patients not having residual tumor, will obviate adjuvant radiotherapy in most cases.

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