A Novel Review on Natural Polymers Used In Formulation of Pharmaceutical Dosage Forms

All pharmaceutical dosage forms contain many additives besides the active ingredients to assist manufacturing and to obtain the desired effect to t he pharmaceutical active ingredients. The advances in drug delivery have simultaneously urged the discove ry of novel excipients which are safe and fulfill specific functions and directly or indirectly influ ence the rate and extent of release and or absorpti on. Earlier used natural excipients are carrageenan, th aumatin, lard, shilajit, aerosil, myrobalan, and st orax. Use of these natural excipients to deliver the bioa ctive agents has been hampered by the synthetic materials. Excipients are any component other than the active substances intentionally added to formulation of a dosage form. Novel drug delivery s ystems are developed to address the challenges of drug development such as bioavailability, permeabil ity, and poor solubility. This review discusses abo ut the majority of these plant-derived polymeric compo unds, their sources extraction procedure, chemical constituents, uses and so delivery system recent in vestigations as excipients in novel drug.

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