CEMIP-mediated hyaluronan metabolism facilitates SCLC metastasis by activating TLR2/c-Src/ERK1/2 axis.

[1]  Pu Zhang,et al.  ATF4/CEMIP/PKCα promotes anoikis resistance by enhancing protective autophagy in prostate cancer cells , 2022 .

[2]  Yuan Tian,et al.  The role of CEMIP in tumors: An update based on cellular and molecular insights. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[3]  P. Iyengar,et al.  Small Cell Lung Cancer, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology. , 2021, Journal of the National Comprehensive Cancer Network : JNCCN.

[4]  S. Tariq,et al.  Update 2021: Management of Small Cell Lung Cancer , 2021, Lung.

[5]  Q. Hua,et al.  CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin , 2021, Oncogene.

[6]  A. Pandit,et al.  Recent advances and prospects of hyaluronan as a multifunctional therapeutic system. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[7]  D. Tian,et al.  The emerging role of KIAA1199 in cancer development and therapy. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[8]  R. Diaz,et al.  The remodelling of actin composition as a hallmark of cancer , 2021, Translational oncology.

[9]  G. Sethi,et al.  A Novel Role of Bergamottin in Attenuating Cancer Associated Cachexia by Diverse Molecular Mechanisms , 2021, Cancers.

[10]  J. Sage,et al.  Mechanisms of small cell lung cancer metastasis , 2020, EMBO molecular medicine.

[11]  E. Feuer,et al.  The Effect of Advances in Lung-Cancer Treatment on Population Mortality. , 2020, The New England journal of medicine.

[12]  N. Mao,et al.  A novel metastatic promoter CEMIP and its downstream molecular targets and signaling pathway of cellular migration and invasion in SCLC cells based on proteome analysis , 2020, Journal of Cancer Research and Clinical Oncology.

[13]  Y. Okada,et al.  Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection , 2020, Cell reports.

[14]  O. Shalem,et al.  The Hyaluronidase, TMEM2, Promotes ER Homeostasis and Longevity Independent of the UPRER , 2019, Cell.

[15]  David R. Jones,et al.  Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis , 2019, Nature Cell Biology.

[16]  Yan Du,et al.  Colorectal cancer‐associated ~ 6 kDa hyaluronan serves as a novel biomarker for cancer progression and metastasis , 2019, The FEBS journal.

[17]  M. Franchi,et al.  Hyaluronan: molecular size‐dependent signaling and biological functions in inflammation and cancer , 2019, The FEBS journal.

[18]  Matthew P. Neilson,et al.  Migration through physical constraints is enabled by MAPK-induced cell softening via actin cytoskeleton re-organization , 2019, Journal of Cell Science.

[19]  E. Turley,et al.  Dissecting the Dual Nature of Hyaluronan in the Tumor Microenvironment , 2019, Front. Immunol..

[20]  R. Savani,et al.  Hyaluronan biology: A complex balancing act of structure, function, location and context. , 2019, Matrix biology : journal of the International Society for Matrix Biology.

[21]  T. L. Andersen,et al.  KIAA1199 is a secreted molecule that enhances osteoblastic stem cell migration and recruitment , 2019, Cell Death & Disease.

[22]  B. Loo,et al.  NCCN Guidelines Insights: Small Cell Lung Cancer, Version 2.2018. , 2018, Journal of the National Comprehensive Cancer Network : JNCCN.

[23]  Qiong Shen,et al.  KIAA1199 promotes metastasis of colorectal cancer cells via microtubule destabilization regulated by a PP2A/stathmin pathway , 2018, Oncogene.

[24]  Roy S. Herbst,et al.  The biology and management of non-small cell lung cancer , 2018, Nature.

[25]  G. Shivashankar,et al.  DNA damage causes rapid accumulation of phosphoinositides for ATR signaling , 2017, Nature Communications.

[26]  Y. Li,et al.  Central Role of CEMIP in Tumorigenesis and Its Potential as Therapeutic Target , 2017, Journal of Cancer.

[27]  N. Sato,et al.  KIAA1199 is induced by inflammation and enhances malignant phenotype in pancreatic cancer , 2017, Oncotarget.

[28]  C. Taniguchi,et al.  Identification of KIAA1199 as a Biomarker for Pancreatic Intraepithelial Neoplasia , 2016, Scientific Reports.

[29]  N. Itano,et al.  Hyaluronan: A modulator of the tumor microenvironment. , 2016, Cancer letters.

[30]  Jill S Barnholtz-Sloan,et al.  Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival , 2015, Oncotarget.

[31]  A. Berns,et al.  Origins, genetic landscape, and emerging therapies of small cell lung cancer , 2015, Genes & development.

[32]  R. Markwald,et al.  Interactions between Hyaluronan and Its Receptors (CD44, RHAMM) Regulate the Activities of Inflammation and Cancer , 2015, Front. Immunol..

[33]  Michelle H. W. Laird,et al.  Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain , 2015, Proceedings of the National Academy of Sciences.

[34]  Yan Du,et al.  A novel role of low molecular weight hyaluronan in breast cancer metastasis , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[35]  Yoshinori Sugiyama,et al.  KIAA1199, a deafness gene of unknown function, is a new hyaluronan binding protein involved in hyaluronan depolymerization , 2013, Proceedings of the National Academy of Sciences.

[36]  Chunyi Zhang,et al.  Trihydrophobin 1 Phosphorylation by c-Src Regulates MAPK/ERK Signaling and Cell Migration , 2012, PloS one.

[37]  A. Prince,et al.  Ca 2 signaling in airway epithelial cells facilitates leukocyte recruitment and transepithelial migration , 2009 .

[38]  P. Sham,et al.  High-throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers. , 2006, Cancer Research.

[39]  G. Prestwich,et al.  Regulation of lung injury and repair by Toll-like receptors and hyaluronan , 2005, Nature Medicine.

[40]  B. Toole,et al.  Hyaluronan: from extracellular glue to pericellular cue , 2004, Nature Reviews Cancer.

[41]  G. Borisy,et al.  Cell Migration: Integrating Signals from Front to Back , 2003, Science.

[42]  Yusuke Nakamura,et al.  Mutations in the gene encoding KIAA1199 protein, an inner-ear protein expressed in Deiters' cells and the fibrocytes, as the cause of nonsyndromic hearing loss , 2003, Journal of Human Genetics.

[43]  Paul J. McLaughlin,et al.  Latrunculin alters the actin-monomer subunit interface to prevent polymerization , 2000, Nature Cell Biology.

[44]  S. Scherer,et al.  The hyaluronidase gene HYAL1 maps to chromosome 3p21.2-p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locus. , 1998, Genomics.

[45]  S. Brenner,et al.  Inhibition of actin polymerization by latrunculin A , 1987, FEBS letters.

[46]  M. Cowman Methods for Hyaluronan Molecular Mass Determination by Agarose Gel Electrophoresis. , 2019, Methods in molecular biology.

[47]  X. Fang,et al.  Silencing of CEMIP suppresses Wnt/β-catenin/Snail signaling transduction and inhibits EMT program of colorectal cancer cells. , 2018, Acta histochemica.

[48]  Erh-Min Lai,et al.  Protein-Protein Interactions: Co-Immunoprecipitation. , 2017, Methods in molecular biology.