Quantum information theory is applied to practical interferometer-based phase measurements to deduce the optimal phase measurement scheme with two optical modes. Optimal phase measurements, given ideal input states, reveal an asymptotic 1/n decrease in phase uncertainty Delta theta for n the mean photon number of the input state. In contradistinction to previous schemes for realizing the number-phase uncertainty limit, the 1/n limit achieved here is independent of the interferometer phase shift; prior information about the expected phase shift is not necessary to attain this limit. These results apply more generally to su(2) and so(3) phase parameter estimation.