Calcium hydroxide induced apexification with apical root development: a clinical case report.

AIM To report the induction of apical root development by calcium hydroxide in teeth with pulp necrosis and periapical radiolucency. SUMMARY A 10-year-old male patient was admitted to the clinic complaining of an intense pain and oedema on the anterior facial region, compatible with an acute dentoalveolar abscess. There was a previous history of dental trauma; only tooth 11 was negative to pulp sensitivity tests. Radiographically, tooth 11 exhibited incomplete root formation, characterized by a wide root canal, thin and fragile dentinal walls, and an extensive, divergent foraminal opening associated with an apical radiolucency. The first appointment focused on urgent local and systemic treatment. Apexification treatment commenced at the second session after 7 days, by means of chemo-mechanical debridement throughout the entire root canal, using K-files and irrigation with a 2.5% sodium hypochlorite solution. Subsequently, a calcium hydroxide paste was applied and changed four times over 8 months, when radiographic examination revealed complete closure of the foraminal opening, resulting in resolution of the periapical radiolucency and associated with 5 mm of additional root development. The root canal was filled by thermomechanical compaction of gutta-percha and sealer. A 3-year follow-up revealed normal periapical tissues and the absence of symptoms. KEY LEARNING POINTS * In young patients, dental trauma may cause pulp necrosis and arrest of root formation. * Under certain circumstances, chemo-mechanical debridement, including the use of a calcium hydroxide paste, is a valid alternative to mineral trioxide aggregate and or surgery for root-end closure. * In teeth with incompletely formed roots associated with periapical lesions, calcium hydroxide can induce periapical repair through the closure of the foramen and apical root development.

[1]  M. Tanomaru-Filho,et al.  Fracture strength of bovine incisors after intra-radicular treatment with MTA in an experimental immature tooth model. , 2007, International endodontic journal.

[2]  G. De-Deus,et al.  The use of white Portland cement as an apical plug in a tooth with a necrotic pulp and wide-open apex: a case report. , 2007, International endodontic journal.

[3]  J. Camilleri Hydration mechanisms of mineral trioxide aggregate. , 2007, International endodontic journal.

[4]  T. Baccetti,et al.  Apical plug technique using mineral trioxide aggregate: results from a case series. , 2007, International endodontic journal.

[5]  P. Machtou,et al.  The use of mineral trioxide aggregate in one-visit apexification treatment: a prospective study. , 2007, International endodontic journal.

[6]  J. Ling,et al.  [Clinical management of open apices teeth with mineral trioxide aggregate (MTA) as apical barrier in adults]. , 2006, Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology.

[7]  E. Nunes,et al.  Nonsurgical treatment of extensive cyst-like periapical lesion of endodontic origin. , 2006, International endodontic journal.

[8]  F. Huang,et al.  [Treatment of teeth with open apices using mineral trioxide aggregate as apical barrier]. , 2006, Shanghai kou qiang yi xue = Shanghai journal of stomatology.

[9]  M. J. Rocha,et al.  The effect of mineral trioxide aggregate on the apexification and periapical healing of teeth with incomplete root formation. , 2006, International endodontic journal.

[10]  E. Araújo,et al.  Physico-chemical properties of MTA and a novel experimental cement. , 2005, International endodontic journal.

[11]  A. Reyes,et al.  Study of calcium hydroxide apexification in 26 young permanent incisors , 2005 .

[12]  M. Rafter Apexification: a review. , 2005, Dental traumatology : official publication of International Association for Dental Traumatology.

[13]  M. Torabinejad Clinical applications of mineral trioxide aggregate. , 1999, The Alpha omegan.

[14]  C. Estrela,et al.  Calcium hydroxide: study based on scientific evidences. , 2003, Journal of applied oral science : revista FOB.

[15]  M. Kuga,et al.  pH and calcium ion release of 2 root-end filling materials. , 2003, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[16]  J. Andreasen,et al.  Long-term calcium hydroxide as a root canal dressing may increase risk of root fracture. , 2002, Dental traumatology : official publication of International Association for Dental Traumatology.

[17]  F. Silveira,et al.  Calcium hydroxide root canal dressing. Histopathological evaluation of periapical repair at different time periods. , 2002, Brazilian dental journal.

[18]  M. Rossi,et al.  Effect of calcium hydroxide on bacterial endotoxin in vivo. , 2002, Journal of endodontics.

[19]  M. Torabinejad,et al.  Treatment of teeth with open apices using mineral trioxide aggregate. , 2000, Practical periodontics and aesthetic dentistry : PPAD.

[20]  J. Siqueira,et al.  Mechanisms of antimicrobial activity of calcium hydroxide: a critical review. , 1999, International endodontic journal.

[21]  R. Holland,et al.  Reaction of rat connective tissue to implanted dentin tubes filled with mineral trioxide aggregate or calcium hydroxide. , 1999, Journal of endodontics.

[22]  P. Cleaton-jones,et al.  A histological and quantitative histomorphometric study of apexification of nonvital permanent incisors of vervet monkeys after repeated root filling with a calcium hydroxide paste. , 1997, Endodontics & dental traumatology.

[23]  R. Leonardo,et al.  Histological evaluation of therapy using a calcium hydroxide dressing for teeth with incompletely formed apices and periapical lesions. , 1993, Journal of endodontics.

[24]  H. Messer,et al.  pH changes in root dentin over a 4-week period following root canal dressing with calcium hydroxide. , 1993, Journal of endodontics.

[25]  A. Consolaro,et al.  Effect of intracanal dressings on repair and apical bridging of teeth with incomplete root formation. , 1993, Endodontics & dental traumatology.

[26]  D. Hartmann,et al.  Odontoblast-like cytodifferentiation of human dental pulp cells in vitro in the presence of a calcium hydroxide-containing cement. , 1991, Archives of oral biology.

[27]  Richard E. Walton,et al.  Principles and Practice of Endodontics , 1989 .

[28]  J. Andreasen,et al.  pH changes in dental tissues after root canal filling with calcium hydroxide. , 1981, Journal of endodontics.

[29]  R. Holland,et al.  A histological study of the effect of calcium hydroxide in the treatment of pulpless teeth of dogs. , 1979 .

[30]  G. Heithersay,et al.  Calcium hydroxide in the treatment of pulpless teeth with associated pathology. , 1975, Journal of the British Endodontic Society.

[31]  R. Holland,et al.  Healing process of teeth with open apices: histological study. , 1971, The Bulletin of Tokyo Dental College.

[32]  S. Seltzer Endodontology; biologic considerations in endodontic procedures , 1971 .

[33]  G. Heithersay Stimulation of root formation in incompletely developed pulpless teeth. , 1970, Oral surgery, oral medicine, and oral pathology.

[34]  C. M. Nolla The development of the permanent teeth , 1960 .