Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration
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Alexander R. Pico | Mark Ellisman | L. Mucke | K. Hanspers | M. Arkin | J. Ryu | Victoria A. Rafalski | A. Meyer-Franke | R. Adams | S. Poda | Pamela E. Rios Coronado | L. Pedersen | Veena P Menon | K. M. Baeten | Shoana L. Sikorski | C. Bedard | Sophia Bardehle | A. S. Mendiola | D. Davalos | Michael R. Machado | Justin P Chan | I. Plastira | Mark A Petersen | S. Pfaff | K. Ang | K. Hallenbeck | Catriona A. Syme | H. Hakozaki | R. Swanson | S. Zamvil | S. Zorn | Stephen Freedman | J. Stavenhagen | R. Nelson | K. Akassoglou | A. Pico | A. Meyer‐Franke | A. Mendiola | R. A. Adams | Mark A. Petersen | Veena Menon | Justin P. Chan | Catriona Syme | Ryan A. Adams | Dimitrios Davalos | Pamela E. Rios Coronado | Andrew S. Mendiola
[1] R. Doolittle,et al. - cross-linking sites in human and bovine fibrin. , 1971, Biochemistry.
[2] S. DeKosky,et al. Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity , 1990, Annals of neurology.
[3] J. Volpe,et al. Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[4] J. Degen,et al. Resolution of spontaneous bleeding events but failure of pregnancy in fibrinogen-deficient mice. , 1995, Genes & development.
[5] S. Holland,et al. The p47phox mouse knock-out model of chronic granulomatous disease , 1995, The Journal of experimental medicine.
[6] T. Bugge,et al. Loss of Fibrinogen Rescues Mice from the Pleiotropic Effects of Plasminogen Deficiency , 1996, Cell.
[7] P. Mannucci,et al. Bleeding and thrombosis in 55 patients with inherited afibrinogenaemia , 1999, British journal of haematology.
[8] A. Sher,et al. Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion , 2000, Molecular and Cellular Biology.
[9] G. Feng,et al. Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP , 2000, Neuron.
[10] M. Smith,et al. Activation of NADPH oxidase in Alzheimer's disease brains. , 2000, Biochemical and biophysical research communications.
[11] B. Hyman,et al. Imaging Aβ Plaques in Living Transgenic Mice with Multiphoton Microscopy and Methoxy‐X04, a Systemically Administered Congo Red Derivative , 2002, Journal of neuropathology and experimental neurology.
[12] K. Akassoglou,et al. Fibrin Inhibits Peripheral Nerve Remyelination by Regulating Schwann Cell Differentiation , 2002, Neuron.
[13] P. Shannon,et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.
[14] Shiori Koseki-Kuno,et al. Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages. , 2003, Blood.
[15] S. Lord,et al. Sequence γ377−395(P2), but Not γ190−202(P1), Is the Binding Site for the αMI-Domain of Integrin αMβ2 in the γC-Domain of Fibrinogen† , 2003 .
[16] D. Witte,et al. Leukocyte engagement of fibrin(ogen) via the integrin receptor αMβ2/Mac-1 is critical for host inflammatory response in vivo , 2004 .
[17] Jean YH Yang,et al. Bioconductor: open software development for computational biology and bioinformatics , 2004, Genome Biology.
[18] A. Mócsai,et al. Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs , 2006, Nature Immunology.
[19] M. Ohno,et al. Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation , 2006, The Journal of Neuroscience.
[20] M. Colonna,et al. Activating and inhibitory functions of DAP12 , 2007, Nature reviews. Immunology.
[21] W. Aird,et al. NADPH Oxidase Activity Selectively Modulates Vascular Endothelial Growth Factor Signaling Pathways* , 2007, Journal of Biological Chemistry.
[22] H. Lassmann,et al. The fibrin-derived γ377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease , 2007, The Journal of experimental medicine.
[23] K. Krause,et al. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. , 2007, Physiological reviews.
[24] H. Lassmann,et al. Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity? , 2007, Brain : a journal of neurology.
[25] Sergio E. Baranzini,et al. Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets , 2008, Nature.
[26] S. Rivest. Regulation of innate immune responses in the brain , 2009, Nature Reviews Immunology.
[27] Hans Lassmann,et al. The relation between inflammation and neurodegeneration in multiple sclerosis brains , 2009, Brain : a journal of neurology.
[28] R. Ransohoff,et al. Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice , 2010, PloS one.
[29] Gary D. Bader,et al. The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function , 2010, Nucleic Acids Res..
[30] H. Lassmann,et al. Oxidative damage in multiple sclerosis lesions , 2011, Brain : a journal of neurology.
[31] Mary T. Brinkoetter,et al. A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis , 2011, Nature Medicine.
[32] D. Davalos,et al. Fibrinogen as a key regulator of inflammation in disease , 2011, Seminars in Immunopathology.
[33] H. Lassmann. Mechanisms of neurodegeneration shared between multiple sclerosis and Alzheimer’s disease , 2011, Journal of Neural Transmission.
[34] C. Iadecola,et al. Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-β , 2011, Proceedings of the National Academy of Sciences.
[35] T. Deerinck,et al. Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation , 2012, Nature Communications.
[36] R. Ransohoff,et al. Innate immunity in the central nervous system. , 2012, The Journal of clinical investigation.
[37] H. Lassmann,et al. Explorer NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury , 2012 .
[38] Hans Lassmann,et al. Progressive multiple sclerosis: pathology and pathogenesis , 2012, Nature Reviews Neurology.
[39] Tracy J. Yuen,et al. M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination , 2013, Nature Neuroscience.
[40] C. Nathan,et al. Beyond oxidative stress: an immunologist's guide to reactive oxygen species , 2013, Nature Reviews Immunology.
[41] L. Tran,et al. Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease , 2013, Cell.
[42] M. Fang,et al. Assessing bleeding risk in patients taking anticoagulants , 2013, Journal of Thrombosis and Thrombolysis.
[43] W. Lam,et al. Factor XIII activity mediates red blood cell retention in venous thrombi. , 2014, Journal of Clinical Investigation.
[44] S. Gygi,et al. Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia , 2013, Nature Neuroscience.
[45] R. Tsien,et al. Early detection of thrombin activity in neuroinflammatory disease , 2014, Annals of neurology.
[46] H. Lassmann,et al. Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models , 2014, Acta Neuropathologica.
[47] Zhen Zhao,et al. Establishment and Dysfunction of the Blood-Brain Barrier , 2015, Cell.
[48] Sara G. Murray,et al. Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation , 2015, Nature Communications.
[49] Sidney Strickland,et al. Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration , 2015, Neurobiology of Aging.
[50] C. Jack,et al. Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly , 2015, Brain : a journal of neurology.
[51] Burkhard Becher,et al. Immune attack: the role of inflammation in Alzheimer disease , 2015, Nature Reviews Neuroscience.
[52] B. Schiøtt,et al. Structural Basis for Simvastatin Competitive Antagonism of Complement Receptor 3* , 2016, The Journal of Biological Chemistry.
[53] Ryan Miller,et al. WikiPathways: capturing the full diversity of pathway knowledge , 2015, Nucleic Acids Res..
[54] Mark Ellisman,et al. Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage , 2017, Neuron.
[55] I. Amit,et al. A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease , 2017, Cell.
[56] R. Vadlamudi,et al. NADPH oxidase in brain injury and neurodegenerative disorders , 2017, Molecular Neurodegeneration.
[57] R. Perera,et al. Fibrin(ogen) and neurodegeneration in the progressive multiple sclerosis cortex , 2017, Annals of neurology.
[58] H. Weiner,et al. CNS inflammation and neurodegeneration. , 2017, The Journal of clinical investigation.
[59] F. Vilhardt,et al. NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease , 2017, British journal of pharmacology.
[60] J. Cummings,et al. Lessons Learned from Alzheimer Disease: Clinical Trials with Negative Outcomes , 2017, Clinical and translational science.
[61] Keith A. Johnson,et al. Interactive Associations of Vascular Risk and &bgr;-Amyloid Burden With Cognitive Decline in Clinically Normal Elderly Individuals: Findings From the Harvard Aging Brain Study , 2018, JAMA Neurology.
[62] S. Strickland. Blood will out: vascular contributions to Alzheimer’s disease , 2018, The Journal of clinical investigation.
[63] J. Ryu,et al. Fibrinogen in neurological diseases: mechanisms, imaging and therapeutics , 2018, Nature Reviews Neuroscience.
[64] B. Becher,et al. High‐Dimensional Single‐Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease , 2018, Immunity.
[65] G. Nolan,et al. Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models , 2018, Nature Neuroscience.
[66] Pascal Sati,et al. Spatiotemporal distribution of fibrinogen in marmoset and human inflammatory demyelination , 2018, Brain : a journal of neurology.
[67] Brenda J Butka. Imaging , 2003, JAMA.