Initial management of upper extremity war injuries

Upper extremity war injuries are complex wounds that include a combination of bone, soft-tissue, and vascular injury, and nerve loss. Treatment begins in theater with initial wound care and provisional skeletal stabilization. Once in the continental United States at a tertiary-care facility, the wounds are further debrided, and definitive treatment is initiated. Definitive treatment involves a multidisciplinary approach to treat all associated injuries. After serial debridement and irrigation to remove all devitalized tissue and contamination, a coordinated plan is made for skeletal stabilization and definitive closure or soft-tissue coverage. Options for skeletal fixation include open reduction internal fixation, external fixation, intramedullary nailing, and cement spacer placement with delayed bone grafting for segmental bone loss. Soft-tissue coverage options include delayed primary closure, dermal substitutes, skin grafting, rotational flaps, pedicled flaps, and free flaps. Treatment decisions are dictated by injury location, size of wounds, and donor site availability. Associated nerve injuries often present with large segmental defects and cannot be repaired acutely. Treatment requires delayed autograft reconstruction, with or without nerve conduits.

[1]  R. Tuan,et al.  Mesenchymal progenitor cells derived from traumatized muscle enhance neurite growth , 2013, Journal of tissue engineering and regenerative medicine.

[2]  W. Ricci,et al.  What's new in orthopaedic trauma. , 2011, The Journal of bone and joint surgery. American volume.

[3]  P. Pasquina,et al.  Dismounted complex blast injury report of the army dismounted complex blast injury task force , 2012 .

[4]  Gabriel F. Santiago,et al.  Soft Tissue Injury Management With a Continuous External Tissue Expander , 2012, Annals of plastic surgery.

[5]  J. Goubier,et al.  Adult post-traumatic radioulnar synostosis. , 2012, Orthopaedics & traumatology, surgery & research : OTSR.

[6]  W. Obremskey,et al.  Use of Negative‐pressure Wound Therapy in Orthopaedic Trauma , 2012, The Journal of the American Academy of Orthopaedic Surgeons.

[7]  M. K. Mukherjee,et al.  Reconstructive challenges in war wounds , 2012, Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India.

[8]  Robert J. Gaines,et al.  Evolution of Orthopaedic Reconstructive Care , 2012, The Journal of the American Academy of Orthopaedic Surgeons.

[9]  M. T. Charlton,et al.  Dismounted Complex Blast Injury. , 2012, Journal of surgical orthopaedic advances.

[10]  R. Andersen,et al.  Dismounted complex blast injuries: patterns of injuries and resource utilization associated with the multiple extremity amputee. , 2012, Journal of surgical orthopaedic advances.

[11]  John F Kragh,et al.  Battle casualty survival with emergency tourniquet use to stop limb bleeding. , 2011, The Journal of emergency medicine.

[12]  S. Mackinnon,et al.  Nerve reconstruction in the hand and upper extremity. , 2011, Clinics in plastic surgery.

[13]  J. Forsberg,et al.  Traumatic and trauma-related amputations: Part II: Upper extremity and future directions. , 2010, The Journal of bone and joint surgery. American volume.

[14]  R. Andersen,et al.  Simultaneous pedicled flaps for coverage of complex blast injuries to the forearm and hand (with supplemental external fixation to the iliac crest for immobilization) , 2010, The Journal of hand surgery, European volume.

[15]  J. Bradley,et al.  Lessons from the modern battlefield: successful upper extremity injury reconstruction in the subacute period. , 2009, The Journal of trauma.

[16]  R. Tuan,et al.  Differentiation potential of multipotent progenitor cells derived from war-traumatized muscle tissue. , 2008, The Journal of bone and joint surgery. American volume.

[17]  G. Baek,et al.  Interlocking contoured intramedullary nail fixation for selected diaphyseal fractures of the forearm in adults. , 2008, The Journal of bone and joint surgery. American volume.

[18]  J. Kalvach,et al.  Interlocking Nailing of Forearm Fractures , 2008, Acta chirurgica Belgica.

[19]  L. Stansbury,et al.  Amputation in military trauma surgery. , 2007, The Journal of trauma.

[20]  M. Mazurek,et al.  Injuries sustained to the upper extremity due to modern warfare and the evolution of care. , 2007, The Journal of hand surgery.

[21]  M. Helgeson,et al.  Bioartificial Dermal Substitute: A Preliminary Report on Its Use for the Management of Complex Combat-Related Soft Tissue Wounds , 2007, Journal of orthopaedic trauma.

[22]  R. Lyons,et al.  Operation Iraqi Freedom: A Report on a Series of Soldiers Treated With Free Tissue Transfer by a Plastic Surgery Service , 2007, Annals of plastic surgery.

[23]  M. Bumbasirevic,et al.  Treatment of Blast Injuries of the Extremity , 2006, The Journal of the American Academy of Orthopaedic Surgeons.

[24]  D. Covey Combat Orthopaedics: A View From the Trenches , 2006, The Journal of the American Academy of Orthopaedic Surgeons.

[25]  L. Iacovitti,et al.  Adult human bone marrow stromal spheres express neuronal traits in vitro and in a rat model of Parkinson's disease , 2006, Brain Research.

[26]  P. Hashmi Free scapular flap for reconstruction of upper extremity defects. , 2004, Journal of the College of Physicians and Surgeons--Pakistan : JCPSP.

[27]  A C Masquelet,et al.  Induced membranes secrete growth factors including vascular and osteoinductive factors and could stimulate bone regeneration , 2004, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[28]  W. Lineaweaver,et al.  Fracture fixation in the mutilated hand. , 2003, Hand clinics.

[29]  D. Erdmann,et al.  Soft tissue coverage in devastating hand injuries. , 2003, Hand clinics.

[30]  M. Neumeister,et al.  Mutilating hand injuries: principles and management. , 2003, Hand clinics.

[31]  S. Lepreux,et al.  Behaviour of cancellous bone graft placed in induced membranes. , 2002, British journal of plastic surgery.

[32]  E. Caterson,et al.  Human marrow-derived mesenchymal progenitor cells , 2002, Molecular biotechnology.

[33]  V. Mićović,et al.  The role of interfascicular nerve grafting after gunshot wounds , 1996, International Orthopaedics.

[34]  P. Manson,et al.  Microvascular Soft‐Tissue Transplantation for Reconstruction of Acute Open Tibial Fractures: Timing of Coverage and Long‐Term Functional Results , 1992, Plastic and reconstructive surgery.

[35]  Masquelet Ac,et al.  Vascularized periosteum associated with cancellous bone graft : an experimental study , 1990 .

[36]  A. Masquelet,et al.  Vascularized Periosteum Associated with Cancellous Bone Graft: An Experimental Study , 1990, Plastic and reconstructive surgery.