Accelerated HER-2 degradation enhanced ovarian tumor recognition by CTL. Implications for tumor immunogenicity
暂无分享,去创建一个
J. Murray | A. Kudelka | D. Gershenson | Eric A Swan | C. Ioannides | N. Ward | C. O'Brian | A. Castilleja | M. A. Gillogly | Bruce II Swearingen | C. O'brian
[1] J. Murray,et al. Peptide priming of cytolytic activity to HER-2 epitope 369-377 in healthy individuals. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[2] P Kronqvist,et al. Cysteine proteinase inhibitor cystatin A in breast cancer. , 1998, Cancer research.
[3] Pamela J. Fink,et al. Maximal Proliferation of Cytotoxic T Lymphocytes Requires Reverse Signaling through Fas Ligand , 1998, The Journal of experimental medicine.
[4] M. D. Val,et al. Selective involvement of proteasomes and cysteine proteases in MHC class I antigen presentation. , 1997, Journal of immunology.
[5] L. Hicke. Ubiquitin‐dependent internalization and down‐regulation of plasma membrane proteins , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[6] C. Pickart. Targeting of substrates to the 26S proteasome , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] A. Goldberg,et al. Two distinct proteolytic processes in the generation of a major histocompatibility complex class I-presented peptide. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[8] D. Hanahan,et al. Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy , 1997, The Journal of experimental medicine.
[9] J. Bluestone,et al. Antigenic Cancer Cells Grow Progressively in Immune Hosts without Evidence for T Cell Exhaustion or Systemic Anergy , 1997, The Journal of experimental medicine.
[10] J. Yewdell,et al. The generation of MHC class I-associated peptides is only partially inhibited by proteasome inhibitors: involvement of nonproteasomal cytosolic proteases in antigen processing? , 1997, Journal of immunology.
[11] R. Siliciano,et al. Targeting of HIV-1 Antigens for Rapid Intracellular Degradation Enhances Cytotoxic T Lymphocyte (CTL) Recognition and the Induction of De Novo CTL Responses In Vivo After Immunization , 1997, The Journal of experimental medicine.
[12] T. Waldmann,et al. Effects of the tyrosine‐kinase inhibitor geldanamycin on ligand‐induced HER‐2/NEU activation, receptor expression and proliferation of HER‐2‐positive malignant cell lines , 1997, International journal of cancer.
[13] E. Halapi,et al. Mechanisms of escape from CD8+ T‐cell clones specific for the HER‐2/NEU proto‐oncogene expressed in ovarian carcinomas: Related and unrelated to decreased MHC class 1 expression , 1997, International journal of cancer.
[14] J. Bryant,et al. Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen. , 1996, The Journal of clinical investigation.
[15] L. Neckers,et al. Polyubiquitination and Proteasomal Degradation of the p185c-erbB-2 Receptor Protein-tyrosine Kinase Induced by Geldanamycin* , 1996, The Journal of Biological Chemistry.
[16] G. Huang,et al. Human Cancer Cells Exhibit Protein Kinase C-dependent c-erbB-2 Transmodulation That Correlates with Phosphatase Sensitivity and Kinase Activity* , 1996, The Journal of Biological Chemistry.
[17] H. Pircher,et al. On the role of antigen in maintaining cytotoxic T-cell memory. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[18] N. Shastri,et al. Generation of naturally processed peptide/MHC class I complexes is independent of the stability of endogenously synthesized precursors. , 1996, Journal of immunology.
[19] J. Yewdell,et al. Defective ribosomal products (DRiPs): a major source of antigenic peptides for MHC class I molecules? , 1996, Journal of immunology.
[20] F. Shanahan,et al. The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand , 1996, The Journal of experimental medicine.
[21] J. Berzofsky,et al. Role of antigen, CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL , 1996, The Journal of experimental medicine.
[22] T. Mak,et al. Duration of TCR stimulation determines costimulatory requirement of T cells. , 1996, Immunity.
[23] J. Bluestone,et al. CD28/B7 system of T cell costimulation. , 1996, Annual review of immunology.
[24] J. Sprent,et al. Influence of antigen dose and costimulation on the primary response of CD8+ T cells in vitro , 1996, The Journal of experimental medicine.
[25] C. Hahn,et al. The requirement for proteasome activity class I major histocompatibility complex antigen presentation is dictated by the length of preprocessed antigen , 1996, The Journal of experimental medicine.
[26] A. Lanzavecchia,et al. Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy , 1996, The Journal of experimental medicine.
[27] L. Neckers,et al. p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2. , 1996, The Journal of biological chemistry.
[28] A. Goldberg,et al. Rate of antigen degradation by the ubiquitin-proteasome pathway influences MHC class I presentation. , 1995, Journal of immunology.
[29] H. Schreiber,et al. Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[30] J. Wharton,et al. Identification of an immunodominant peptide of HER-2/neu protooncogene recognized by ovarian tumor-specific cytotoxic T lymphocyte lines , 1995, The Journal of Experimental Medicine.
[31] N. Ward,et al. Irreversible Inactivation of Protein Kinase C by a Peptide-Substrate Analog (*) , 1995, The Journal of Biological Chemistry.
[32] J. Yewdell,et al. Presentation of endogenous and exogenous antigens is not affected by inactivation of E1 ubiquitin-activating enzyme in temperature-sensitive cell lines. , 1995, Journal of Immunology.
[33] D. Margulies,et al. Determinant selection of major histocompatibility complex class I- restricted antigenic peptides is explained by class I-peptide affinity and is strongly influenced by nondominant anchor residues , 1994, The Journal of experimental medicine.
[34] A. Goldberg,et al. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules , 1994, Cell.
[35] A. Houghton. Cancer antigens: immune recognition of self and altered self , 1994, The Journal of experimental medicine.
[36] J. Wharton,et al. Sequence motifs of human her-2 protooncogene important for Peptide binding to hla-A2. , 1994, International journal of oncology.
[37] J. Renauld,et al. A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas , 1994, The Journal of experimental medicine.
[38] M. Cheever,et al. In vitro generation of human cytolytic T-cells specific for peptides derived from the HER-2/neu protooncogene protein. , 1994, Cancer research.
[39] J. Wharton,et al. Cytotoxic T cells isolated from ovarian malignant ascites recognize a peptide derived from the HER-2/neu proto-oncogene. , 1993, Cellular immunology.
[40] A. Goldberg,et al. A role for the ubiquitin-dependent proteolytic pathway in MHC class l-restricted antigen presentation , 1993, Nature.
[41] M. Grooteclaes,et al. Expression of the c-erbB2 gene in the BT474 human mammary tumor cell line: measurement of c-erbB2 mRNA half-life. , 1993, Oncogene.
[42] Y. Yarden,et al. Cell‐type specific interaction of Neu differentiation factor (NDF/heregulin) with Neu/HER‐2 suggests complex ligand‐receptor relationships. , 1993, The EMBO journal.
[43] O. Larsson,et al. Carcinomas and Melanomas CTL Against Autologous and Allogeneic Peptide Epitopes That Can Elicit Specific Derived neu-Identification of New HER 2 / , 1999 .
[44] D. Hanahan,et al. Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice. , 1996, The Journal of clinical investigation.
[45] Gerold Schuler,et al. Dendritic Cells as Adjuvants for Immune-mediated Resistance to Tumors , 1997, The Journal of experimental medicine.