The CASBAH: a searchable database of caspase substrates
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[1] J Downward,et al. Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain , 2002, Cell Death and Differentiation.
[2] Xiaodong Wang,et al. DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis , 1997, Cell.
[3] Colin Adrain,et al. Executioner Caspase-3, -6, and -7 Perform Distinct, Non-redundant Roles during the Demolition Phase of Apoptosis* , 2001, The Journal of Biological Chemistry.
[4] Jason C. Mills,et al. Apoptotic Membrane Blebbing Is Regulated by Myosin Light Chain Phosphorylation , 1998, The Journal of cell biology.
[5] M. Leist,et al. Triggering of apoptosis by cathepsins , 2001, Cell Death and Differentiation.
[6] Y. Lazebnik,et al. Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[7] Seamus J. Martin,et al. Apoptosomes: protease activation platforms to die from. , 2006, Trends in biochemical sciences.
[8] J. Bertoglio,et al. Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing , 2001, Nature Cell Biology.
[9] N. Thornberry,et al. A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B , 1997, The Journal of Biological Chemistry.
[10] D. Green,et al. Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis. , 1992, Cancer research.
[11] Markus Rehm,et al. Single-cell Fluorescence Resonance Energy Transfer Analysis Demonstrates That Caspase Activation during Apoptosis Is a Rapid Process , 2002, The Journal of Biological Chemistry.
[12] Alan G. Porter,et al. Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis* , 1998, The Journal of Biological Chemistry.
[13] D. Green,et al. The role of ARK in stress-induced apoptosis in Drosophila cells , 2002, The Journal of cell biology.
[14] Xiaodong Wang,et al. Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors , 1998, Cell.
[15] Guido Kroemer,et al. Caspase-independent cell death , 2005, Nature Medicine.
[16] H. Horvitz,et al. Genetic control of programmed cell death in the nematode C. elegans , 1986, Cell.
[17] R. Flavell,et al. Caspase knockouts: matters of life and death , 1999, Cell Death and Differentiation.
[18] John Savill,et al. A blast from the past: clearance of apoptotic cells regulates immune responses , 2002, Nature Reviews Immunology.
[19] S. Lowe,et al. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. , 1998, Genes & development.
[20] M. Arcaro,et al. The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila , 2005, Development.
[21] Richard A Flavell,et al. Role of the Executioner Caspases during Lens Development* , 2004, Journal of Biological Chemistry.
[22] J Fernando Bazan,et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. , 2005, Immunity.
[23] S. Baksh,et al. Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal , 2003, Cell.
[24] Eugene M. Johnson,et al. Caspase Inhibition Extends the Commitment to Neuronal Death Beyond Cytochrome c Release to the Point of Mitochondrial Depolarization , 2000, The Journal of cell biology.
[25] Emad S. Alnemri,et al. Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner , 1999, The Journal of cell biology.
[26] Holly McDonough,et al. Reduced Apaf-1 levels in cardiomyocytes engage strict regulation of apoptosis by endogenous XIAP , 2005, The Journal of cell biology.
[27] D. Green,et al. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl , 1995, The Journal of experimental medicine.
[28] Keisuke Kuida,et al. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice , 1996, Nature.
[29] I. Hariharan,et al. The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death , 2006, The Journal of cell biology.
[30] E. Sahai,et al. Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I , 2001, Nature Cell Biology.
[31] C. Stewart,et al. Actin-myosin–based contraction is responsible for apoptotic nuclear disintegration , 2005, The Journal of cell biology.
[32] G. Evan,et al. Inhibition of Ced-3/ICE-related Proteases Does Not Prevent Cell Death Induced by Oncogenes, DNA Damage, or the Bcl-2 Homologue Bak , 1997, The Journal of cell biology.
[33] S. Martin,et al. The mitochondrial apoptosome: a killer unleashed by the cytochrome seas. , 2001, Trends in biochemical sciences.
[34] A. Wyllie,et al. Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics , 1972, British Journal of Cancer.
[35] Francesco Cecconi,et al. Apaf1 (CED-4 Homolog) Regulates Programmed Cell Death in Mammalian Development , 1998, Cell.
[36] Patrick Ng,et al. Caspase-3 Is Required for α-Fodrin Cleavage but Dispensable for Cleavage of Other Death Substrates in Apoptosis* , 1998, The Journal of Biological Chemistry.
[37] F. Martinon,et al. Activation of a pro‐apoptotic amplification loop through inhibition of NF‐κB‐dependent survival signals by caspase‐mediated inactivation of RIP , 2000, FEBS letters.
[38] Tak W. Mak,et al. Two Distinct Pathways Leading to Nuclear Apoptosis , 2000, The Journal of experimental medicine.
[39] Y. Lazebnik,et al. Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[40] H. Horvitz,et al. Mutational analysis of the Caenorhabditis elegans cell-death gene ced-3. , 1999, Genetics.
[41] G. Salvesen,et al. Biochemical Characteristics of Caspases-3, -6, -7, and -8* , 1997, The Journal of Biological Chemistry.
[42] Y. Lin,et al. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. , 1999, Genes & development.
[43] Seamus J. Martin,et al. The Apoptosome Pathway to Caspase Activation in Primary Human Neutrophils Exhibits Dramatically Reduced Requirements for Cytochrome c , 2003, The Journal of experimental medicine.
[44] Seamus J. Martin,et al. Phosphatidylserine Externalization during CD95-induced Apoptosis of Cells and Cytoplasts Requires ICE/CED-3 Protease Activity* , 1996, The Journal of Biological Chemistry.
[45] Junying Yuan,et al. Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis , 1998, Cell.
[46] Seamus J. Martin. Destabilizing Influences in Apoptosis Sowing the Seeds of IAP Destruction , 2002, Cell.
[47] A. Wyllie. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation , 1980, Nature.
[48] S. Goff. Genetic Control of Programmed Cell Death in the Nematode Caenorhabditis elegans 1 , 2007 .
[49] G. Salvesen,et al. The protein structures that shape caspase activity, specificity, activation and inhibition. , 2004, The Biochemical journal.
[50] Sharad Kumar,et al. Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis. , 2004, Developmental cell.
[51] D. Green,et al. Do inducers of apoptosis trigger caspase-independent cell death? , 2005, Nature Reviews Molecular Cell Biology.
[52] K. Schulze-Osthoff,et al. The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice. , 1999, Immunity.
[53] C. Borner,et al. Serine proteases mediate apoptosis-like cell death and phagocytosis under caspase-inhibiting conditions , 2003, Cell Death and Differentiation.
[54] Keisuke Kuida,et al. Caspases 3 and 7: Key Mediators of Mitochondrial Events of Apoptosis , 2006, Science.
[55] E. White,et al. Lamin proteolysis facilitates nuclear events during apoptosis , 1996, The Journal of cell biology.
[56] Antony Rodriguez,et al. The apical caspase dronc governs programmed and unprogrammed cell death in Drosophila. , 2004, Developmental cell.
[57] M MacFarlane,et al. Distinct Caspase Cascades Are Initiated in Receptor-mediated and Chemical-induced Apoptosis* , 1999, The Journal of Biological Chemistry.
[58] E. Simpson,et al. Caspase-7 Expanded Function and Intrinsic Expression Level Underlies Strain-Specific Brain Phenotype of Caspase-3-Null Mice , 2004, The Journal of Neuroscience.