Frailty: Diagnosis and management

[1]  W. Langholff,et al.  An open-label, randomized, multicenter, controlled study of epoetin alfa for the treatment of anemia of chronic kidney disease in the long term care setting. , 2012, Journal of the American Medical Directors Association.

[2]  Luigi Ferrucci,et al.  Sarcopenia with limited mobility: an international consensus. , 2011, Journal of the American Medical Directors Association.

[3]  L. Ferrucci,et al.  International working group on Sarcopenia , 2011 .

[4]  T. Travison,et al.  Changes in reproductive hormone concentrations predict the prevalence and progression of the frailty syndrome in older men: the concord health and ageing in men project. , 2011, The Journal of clinical endocrinology and metabolism.

[5]  Sandrine Andrieu,et al.  Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. , 2011, Journal of the American Medical Directors Association.

[6]  A. Silman,et al.  Frailty in Relation to Variations in Hormone Levels of the Hypothalamic–Pituitary–Testicular Axis in Older Men: Results From the European Male Aging Study , 2011, Journal of the American Geriatrics Society.

[7]  D. Muzio,et al.  Effect of vitamin D nutritional status on muscle function and strength in healthy women aged over sixty-five years , 2011, The journal of nutrition, health & aging.

[8]  Anthony A. Vandervoort,et al.  The Effectiveness of Exercise Interventions for the Management of Frailty: A Systematic Review , 2011, Journal of aging research.

[9]  Rose Anne Kenny,et al.  Continuous Noninvasive Orthostatic Blood Pressure Measurements and Their Relationship with Orthostatic Intolerance, Falls, and Frailty in Older People , 2011, Journal of the American Geriatrics Society.

[10]  G. Abellán van Kan,et al.  Is the mini nutritional assessment an appropriate tool to assess frailty in older adults? , 2011, The journal of nutrition, health & aging.

[11]  M. Mirarefin,et al.  Predicting the value of the mini nutritional assessment (MNA) as an indicator of functional ability in older Iranian adults (Kahrizak elderly study) , 2011, The journal of nutrition, health & aging.

[12]  M. Herrmann,et al.  Supplementation with vitamin D and calcium in long-term care residents. , 2011, Journal of the American Medical Directors Association.

[13]  L. Ferrucci,et al.  Validation of a modified-multidimensional prognostic index (m-MPI) including the mini nutritional assessment short-form (MNA-SF) for the prediction of one-year mortality in hospitalized elderly patients , 2011, The journal of nutrition, health & aging.

[14]  J. Morley,et al.  Assessment of malnutrition in older persons: A focus on the mini nutritional assessment , 2011, The journal of nutrition, health & aging.

[15]  Thuy-Tien L. Dam,et al.  Circulating 25‐Hydroxyvitamin D Levels and Frailty in Older Men: The Osteoporotic Fractures in Men Study , 2011, Journal of the American Geriatrics Society.

[16]  L. Quach,et al.  Dietary protein intake and subsequent falls in older men and women: The Framingham study , 2010, The journal of nutrition, health & aging.

[17]  K. Yoshizaki,et al.  Down-regulation of hepcidin resulting from long-term treatment with an anti-IL-6 receptor antibody (tocilizumab) improves anemia of inflammation in multicentric Castleman disease. , 2010, Blood.

[18]  C. Vergani,et al.  Social vulnerability, mental health and correlates of frailty in older outpatients living alone in the community in Italy , 2010, Aging & mental health.

[19]  G. Ostir,et al.  Cognitive status and future risk of frailty in older Mexican Americans. , 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.

[20]  F. Iellamo,et al.  Testosterone therapy in women with chronic heart failure: a pilot double-blind, randomized, placebo-controlled study. , 2010, Journal of the American College of Cardiology.

[21]  J. Morley Anabolic steroids and frailty. , 2010, Journal of the American Medical Directors Association.

[22]  R. Feinn,et al.  Dehydroepiandrosterone Combined with Exercise Improves Muscle Strength and Physical Function in Frail Older Women , 2010, Journal of the American Geriatrics Society.

[23]  N. Bean,et al.  An analysis of the interactions between individual comorbidities and their treatments--implications for guidelines and polypharmacy. , 2010, Journal of the American Medical Directors Association.

[24]  Rose Anne Kenny,et al.  A Frailty Instrument for primary care: findings from the Survey of Health, Ageing and Retirement in Europe (SHARE) , 2010, BMC geriatrics.

[25]  C. Annweiler,et al.  Falls’ and fallers’ profiles , 2010, The journal of nutrition, health & aging.

[26]  A. Jette,et al.  Adverse events associated with testosterone administration. , 2010, The New England journal of medicine.

[27]  L. Ferrucci,et al.  Nutritional recommendations for the management of sarcopenia. , 2010, Journal of the American Medical Directors Association.

[28]  G. Hankey,et al.  Low free testosterone predicts frailty in older men: the health in men study. , 2010, The Journal of clinical endocrinology and metabolism.

[29]  R. Gobbens,et al.  In search of an integral conceptual definition of frailty: opinions of experts. , 2010, Journal of the American Medical Directors Association.

[30]  T. Travison,et al.  Frailty, serum androgens, and the CAG repeat polymorphism: results from the Massachusetts Male Aging Study. , 2010, The Journal of clinical endocrinology and metabolism.

[31]  J. Judge,et al.  Effects of Transdermal Testosterone on Bone and Muscle in Older Men with Low Bioavailable Testosterone Levels, Low Bone Mass, and Physical Frailty , 2010, Journal of the American Geriatrics Society.

[32]  R. Gobbens,et al.  Determinants of frailty. , 2010, Journal of the American Medical Directors Association.

[33]  R. Écochard,et al.  Effects of branched amino acids supplementation in malnourished elderly with catabolic status , 2010, The journal of nutrition, health & aging.

[34]  J. Morley Clinical practice in nursing homes as a key for progress , 2010, The journal of nutrition, health & aging.

[35]  E. Norkus,et al.  High prevalence of chronic kidney disease, anemia, and falls in an urban long-term care facility: relationship or coincidence? , 2010, Journal of the American Medical Directors Association.

[36]  S. Anker,et al.  Consensus on cachexia definitions. , 2010, Journal of the American Medical Directors Association.

[37]  J. Morley Anorexia, weight loss, and frailty. , 2010, Journal of the American Medical Directors Association.

[38]  J. Gau Prevalence of vitamin D deficiency/insufficiency practice patterns in nursing homes. , 2010, Journal of the American Medical Directors Association.

[39]  J. Morley Hypertension: is it overtreated in the elderly? , 2010, Journal of the American Medical Directors Association.

[40]  W. Banks,et al.  Higher C-reactive protein and soluble tumor necrosis factor receptor levels are associated with poor physical function and disability: a cross-sectional analysis of a cohort of late middle-aged African Americans. , 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.

[41]  David A Bennett,et al.  Physical Frailty Is Associated with Incident Mild Cognitive Impairment in Community‐Based Older Persons , 2010, Journal of the American Geriatrics Society.

[42]  Shwu-chong Wu,et al.  The effectiveness of a comprehensive geriatric assessment intervention program for frailty in community-dwelling older people: a randomized, controlled trial. , 2010, Archives of gerontology and geriatrics.

[43]  S. Roberts,et al.  Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study. , 2010, The Journal of clinical endocrinology and metabolism.

[44]  A. Mitnitski,et al.  Comparison of two frailty measures in the Conselice Study of Brain Ageing , 2010 .

[45]  Dorothee Volkert,et al.  Undiagnosed malnutrition and nutrition-related problems in geriatric patients , 2010, The journal of nutrition, health & aging.

[46]  A. Chakravarti,et al.  Transcobalamin-II variants, decreased vitamin B12 availability and increased risk of frailty , 2009, The journal of nutrition, health & aging.

[47]  A. LaCroix,et al.  Protein Intake and Incident Frailty in the Women's Health Initiative Observational Study , 2010, Journal of the American Geriatrics Society.

[48]  M. Inzitari,et al.  Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force , 2009, The journal of nutrition, health & aging.

[49]  C. Peng,et al.  Frailty and the degradation of complex balance dynamics during a dual-task protocol. , 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

[50]  J. E. Morley Vitamin d redux. , 2009, Journal of the American Medical Directors Association.

[51]  T. Dharmarajan,et al.  Erythropoiesis-stimulating agents in anemia: use and misuse. , 2009, Journal of the American Medical Directors Association.

[52]  B. Vellas,et al.  Validation of the Mini Nutritional Assessment short-form (MNA®-SF): A practical tool for identification of nutritional status , 2009, The journal of nutrition, health & aging.

[53]  G. A. Kan Epidemiology and consequences of sarcopenia. , 2009 .

[54]  H. Bischoff-Ferrari,et al.  Validated treatments and therapeutic perspectives regarding nutritherapy , 2009 .

[55]  M. Pahor,et al.  Carla Task Force on Sarcopenia: Propositions for clinical trials , 2009, The journal of nutrition, health & aging.

[56]  J. Morley,et al.  Developing novel therapeutic approaches to frailty. , 2009, Current pharmaceutical design.

[57]  T. Baydar,et al.  Polypharmacy in the elderly: a multicenter study. , 2009, Journal of the American Medical Directors Association.

[58]  F. Iellamo,et al.  Effect of long-acting testosterone treatment on functional exercise capacity, skeletal muscle performance, insulin resistance, and baroreflex sensitivity in elderly patients with chronic heart failure a double-blind, placebo-controlled, randomized study. , 2009, Journal of the American College of Cardiology.

[59]  L. Wahren,et al.  Importance of dietary advice, nutritional supplements and compliance for maintaining body weight and body fat after hip fracture , 2009, The journal of nutrition, health & aging.

[60]  R. Gobbens,et al.  Towards an integral conceptual model of frailty , 2009 .

[61]  C. Annweiler,et al.  Vitamin D-related changes in physical performance: A systematic review , 2009, The journal of nutrition, health & aging.

[62]  B. Sidenvall,et al.  Who will become malnourished? A prospective study of factors associated with malnutrition in older persons living at home , 2009, The journal of nutrition, health & aging.

[63]  G. Chertow,et al.  Frailty and chronic kidney disease: the Third National Health and Nutrition Evaluation Survey. , 2009, The American journal of medicine.

[64]  R. Varadhan,et al.  Frailty and impaired cardiac autonomic control: new insights from principal components aggregation of traditional heart rate variability indices. , 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

[65]  M. Schuster,et al.  USAGE of megestrol acetate in the treatment of anorexia-cachexia syndrome in the elderly , 2009, The journal of nutrition, health & aging.

[66]  M. Schuurmans,et al.  Frailty: Defining and measuring of a concept , 2009, The journal of nutrition, health & aging.

[67]  S. Conroy,et al.  Defining frailty — the holy grail of geriatric medicine , 2009, The journal of nutrition, health & aging.

[68]  C. Blaum,et al.  Comparing Models of Frailty: The Health and Retirement Study , 2009, Journal of the American Geriatrics Society.

[69]  L. Dubé,et al.  The evolution of nutritional status of geriatric patients without cachexia is associated with food intake in sub-acute care , 2009, The journal of nutrition, health & aging.

[70]  C. Annweiler,et al.  Is there an association between serum 25-hydroxyvitamin D concentration and muscle strength among older women? Results from baseline assessment of the EPIDOS study , 2009, The journal of nutrition, health & aging.

[71]  S. Anker,et al.  Cachexia and aging: An update based on the fourth international cachexia meeting , 2009, The journal of nutrition, health & aging.

[72]  L. Fredman,et al.  Positive Affect and Incidence of Frailty in Elderly Women Caregivers and Noncaregivers: Results of Caregiver–Study of Osteoporotic Fractures , 2009, Journal of the American Geriatrics Society.

[73]  Jean-François Dartigues,et al.  Cognitive Impairment Improves the Predictive Validity of the Phenotype of Frailty for Adverse Health Outcomes: The Three‐City Study , 2009, Journal of the American Geriatrics Society.

[74]  D. Globe,et al.  Chronic kidney disease, anemia, and the association between chronic kidney disease-related anemia and activities of daily living in older nursing home residents. , 2009, Journal of the American Medical Directors Association.

[75]  Kelly R Evenson,et al.  Physical activity as a preventative factor for frailty: the health, aging, and body composition study. , 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

[76]  S. Bandinelli,et al.  Association of low vitamin D levels with the frailty syndrome in men and women. , 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

[77]  J. Morais,et al.  The physical functional capacity of frail elderly persons undergoing ambulatory rehabilitation is related to their nutritional status , 2008, The journal of nutrition, health & aging.

[78]  I. Thompson,et al.  Investigation, treatment and monitoring of late-onset hypogonadism in males , 2008, European journal of endocrinology.

[79]  A. Artz Anemia and the frail elderly. , 2008, Seminars in hematology.

[80]  J. Bauer,et al.  Sarcopenia in nursing home residents. , 2008, Journal of the American Medical Directors Association.

[81]  J. E. Morley,et al.  Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives , 2008, The journal of nutrition, health & aging.

[82]  Y. Rolland,et al.  Physical activity and Alzheimer's disease: from prevention to therapeutic perspectives. , 2008, Journal of the American Medical Directors Association.

[83]  R. Melis,et al.  A randomized study of a multidisciplinary program to intervene on geriatric syndromes in vulnerable older people who live at home (Dutch EASYcare Study). , 2008, The journals of gerontology. Series A, Biological sciences and medical sciences.

[84]  Y. Rolland,et al.  Frailty: toward a clinical definition. , 2008, Journal of the American Medical Directors Association.

[85]  J. E. Morley,et al.  The I.A.N.A. task force on frailty assessment of older people in clinical practice , 2008, The journal of nutrition, health & aging.

[86]  J. Morley Weight loss in older persons: new therapeutic approaches. , 2007, Current pharmaceutical design.

[87]  A. Mitnitski,et al.  How should we grade frailty in nursing home patients? , 2007, Journal of the American Medical Directors Association.

[88]  Matthew T. Haren,et al.  Lower serum DHEAS levels are associated with a higher degree of physical disability and depressive symptoms in middle-aged to older African American women. , 2007, Maturitas.

[89]  J. Cauley,et al.  Frailty and risk of falls, fracture, and mortality in older women: the study of osteoporotic fractures. , 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.

[90]  A. Mitnitski,et al.  A comparison of two approaches to measuring frailty in elderly people. , 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.

[91]  L. Fried,et al.  Denture use, malnutrition, frailty, and mortality among older women living in the community. , 2006, The journal of nutrition, health & aging.

[92]  E. V. van Beek,et al.  Testosterone therapy in men with moderate severity heart failure: a double-blind randomized placebo controlled trial. , 2006, European heart journal.

[93]  Kenneth Rockwood,et al.  What would make a definition of frailty successful? , 2005, Age and ageing.

[94]  L. Ferrucci,et al.  Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. , 2004, The journals of gerontology. Series A, Biological sciences and medical sciences.

[95]  Douglas K. Miller,et al.  Editorial: Something about frailty. , 2002, The journals of gerontology. Series A, Biological sciences and medical sciences.

[96]  J. Morley,et al.  Effect of liquid dietary supplements on energy intake in the elderly. , 2002, The American journal of clinical nutrition.

[97]  Suzanne G. Leveille,et al.  Preventing Disability and Managing Chronic Illness in Frail Older Adults: A Randomized Trial of a Community‐Based Partnership with Primary Care , 1998, Journal of the American Geriatrics Society.

[98]  W. Strawbridge,et al.  Antecedents of frailty over three decades in an older cohort. , 1998, The journals of gerontology. Series B, Psychological sciences and social sciences.

[99]  S B Roberts,et al.  Exercise training and nutritional supplementation for physical frailty in very elderly people. , 1994, The New England journal of medicine.

[100]  L. Rubenstein,et al.  An In‐Home Preventive Assessment Program for Independent Older Adults: A Randomized Controlled Trial , 1994, Journal of the American Geriatrics Society.