Tissue Engineering: The Therapeutic Strategy of the Twenty-First Century

[1]  Nicholas J. Mankovich,et al.  The display of three-dimensional anatomy with stereolithographic models , 1990, Journal of Digital Imaging.

[2]  Seeram Ramakrishna,et al.  Design strategies of tissue engineering scaffolds with controlled fiber orientation. , 2007, Tissue engineering.

[3]  Kwideok Park,et al.  Thermosensitive and Cell-Adhesive Pluronic Hydrogels for Human Adipose-Derived Stem Cells , 2007 .

[4]  S. Wilton,et al.  Antisense oligonucleotide-induced exon skipping across the human dystrophin gene transcript. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

[5]  Robert Langer,et al.  Rapid Optimization of Gene Delivery by Parallel End-modification of Poly(β-amino ester)s. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

[6]  Daniel G. Anderson,et al.  Nanoparticulate delivery of suicide DNA to murine prostate and prostate tumors , 2007, The Prostate.

[7]  R. Tuan,et al.  Comparison of Proliferative and Multilineage Differentiation Potential of Human Mesenchymal Stem Cells Derived from Umbilical Cord and Bone Marrow , 2007, Stem cells.

[8]  J. Tessmar,et al.  Matrices and scaffolds for protein delivery in tissue engineering. , 2007, Advanced drug delivery reviews.

[9]  K. Shakesheff,et al.  Polymer carriers for drug delivery in tissue engineering. , 2007, Advanced drug delivery reviews.

[10]  Fabrizio Gelain,et al.  Designer self-assembling peptide scaffolds for 3-d tissue cell cultures and regenerative medicine. , 2007, Macromolecular bioscience.

[11]  Daniel G. Anderson,et al.  Electrostatic ligand coatings of nanoparticles enable ligand-specific gene delivery to human primary cells. , 2007, Nano letters.

[12]  M. Yamazaki,et al.  Antisense oligonucleotide targeting fibroblast growth factor receptor (FGFR)‐1 stimulates cellular activity of hair follicles in an in vitro organ culture system , 2007, International journal of dermatology.

[13]  Michael J Yaszemski,et al.  Poly(propylene fumarate) bone tissue engineering scaffold fabrication using stereolithography: effects of resin formulations and laser parameters. , 2007, Biomacromolecules.

[14]  E. Jabbari,et al.  Material properties and cytocompatibility of injectable MMP degradable poly(lactide ethylene oxide fumarate) hydrogel as a carrier for marrow stromal cells. , 2007, Biomacromolecules.

[15]  Hyoun‐Ee Kim,et al.  Fabrication of hydroxyapatite-poly(ε-caprolactone) scaffolds by a combination of the extrusion and bi-axial lamination processes , 2007 .

[16]  Gabriele Grimm,et al.  Development of a new calcium phosphate powder-binder system for the 3D printing of patient specific implants , 2007, Journal of materials science. Materials in medicine.

[17]  J. Tessmar,et al.  Customized PEG-derived copolymers for tissue-engineering applications. , 2007, Macromolecular bioscience.

[18]  F. E. Wiria,et al.  Poly-ε-caprolactone/hydroxyapatite for tissue engineering scaffold fabrication via selective laser sintering , 2007 .

[19]  David J. Mooney,et al.  Spatio–temporal VEGF and PDGF Delivery Patterns Blood Vessel Formation and Maturation , 2007, Pharmaceutical Research.

[20]  David Butler,et al.  Tissue engineering and developmental biology: going biomimetic. , 2006, Tissue engineering.

[21]  David L Kaplan,et al.  Tissue engineering: the next generation. , 2006, Tissue engineering.

[22]  R. Izadpanah,et al.  Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue , 2006, Journal of cellular biochemistry.

[23]  G. Vunjak‐Novakovic,et al.  Engineering complex tissues. , 2006, Tissue engineering.

[24]  Daniel Howard,et al.  Zonal release of proteins within tissue engineering scaffolds , 2006, Journal of materials science. Materials in medicine.

[25]  Soong Ho Um,et al.  Enzyme-catalysed assembly of DNA hydrogel , 2006, Nature materials.

[26]  Eleftherios Sachlos,et al.  Collagen scaffolds reinforced with biomimetic composite nano-sized carbonate-substituted hydroxyapatite crystals and shaped by rapid prototyping to contain internal microchannels. , 2006, Tissue engineering.

[27]  R. Langer,et al.  In situ cross-linkable hyaluronic acid hydrogels prevent post-operative abdominal adhesions in a rabbit model. , 2006, Biomaterials.

[28]  Daniel G. Anderson,et al.  Biodegradable polymeric vectors for gene delivery to human endothelial cells. , 2006, Bioconjugate chemistry.

[29]  Ryan B. Wicker,et al.  Stereolithography of Three-Dimensional Bioactive Poly(Ethylene Glycol) Constructs with Encapsulated Cells , 2006, Annals of Biomedical Engineering.

[30]  J. Elisseeff,et al.  The role of biomaterials in stem cell differentiation: applications in the musculoskeletal system. , 2006, Stem cells and development.

[31]  L. Benowitz,et al.  Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells , 2006, Nature Neuroscience.

[32]  K. Maruyama,et al.  A Comparison of Neural Differentiation and Retinal Transplantation with Bone Marrow‐Derived Cells and Retinal Progenitor Cells , 2006, Stem cells.

[33]  Robert L Sah,et al.  Probing the role of multicellular organization in three-dimensional microenvironments , 2006, Nature Methods.

[34]  Seeram Ramakrishna,et al.  Nano-featured scaffolds for tissue engineering: a review of spinning methodologies. , 2006, Tissue engineering.

[35]  M. Shoichet,et al.  Immobilized concentration gradients of neurotrophic factors guide neurite outgrowth of primary neurons in macroporous scaffolds. , 2006, Tissue engineering.

[36]  N. Cabrol,et al.  Dual release of proteins from porous polymeric scaffolds. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[37]  M. Bissell,et al.  Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. , 2006, Annual review of cell and developmental biology.

[38]  D. Mooney,et al.  Regulating activation of transplanted cells controls tissue regeneration. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[39]  Somponnat Sampattavanich,et al.  Effects of Three‐Dimensional Culture and Growth Factors on the Chondrogenic Differentiation of Murine Embryonic Stem Cells , 2006, Stem cells.

[40]  Kristi S Anseth,et al.  Dexamethasone-functionalized gels induce osteogenic differentiation of encapsulated hMSCs. , 2006, Journal of biomedical materials research. Part A.

[41]  D. Kaplan,et al.  Biopolymer-based biomaterials as scaffolds for tissue engineering. , 2006, Advances in biochemical engineering/biotechnology.

[42]  C. Cetrulo.  Cord-blood mesenchymal stem cells and tissue engineering , 2006, Stem cell reviews.

[43]  Cato T Laurencin,et al.  Polymers as biomaterials for tissue engineering and controlled drug delivery. , 2006, Advances in biochemical engineering/biotechnology.

[44]  Paul Roschger,et al.  Biomimetic mineral-organic composite scaffolds with controlled internal architecture , 2005, Journal of materials science. Materials in medicine.

[45]  Robert Langer,et al.  A family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gene delivery. , 2005, Angewandte Chemie.

[46]  Y. Nahmias,et al.  Laser-guided direct writing for three-dimensional tissue engineering. , 2005, Biotechnology and bioengineering.

[47]  Shuguang Zhang,et al.  Designer self-assembling peptide nanofiber scaffolds for 3D tissue cell cultures. , 2005, Seminars in cancer biology.

[48]  M. A. Wettergreen,et al.  Computer-Aided Tissue Engineering of a Human Vertebral Body , 2005, Annals of Biomedical Engineering.

[49]  P. Manson,et al.  The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells. , 2005, Biomaterials.

[50]  Jong-sang Park,et al.  Synthesis of biodegradable cross-linked poly(beta-amino ester) for gene delivery and its modification, inducing enhanced transfection efficiency and stepwise degradation. , 2005, Bioconjugate chemistry.

[51]  D. Kaplan,et al.  Porosity of 3D biomaterial scaffolds and osteogenesis. , 2005, Biomaterials.

[52]  Colleen L Flanagan,et al.  Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering. , 2005, Biomaterials.

[53]  Samuel I Stupp,et al.  Self-assembling peptide amphiphile nanofiber matrices for cell entrapment. , 2005, Acta biomaterialia.

[54]  Daniel W. Pack,et al.  Design and development of polymers for gene delivery , 2005, Nature Reviews Drug Discovery.

[55]  S. Hollister.  Porous scaffold design for tissue engineering , 2005, Nature materials.

[56]  W. Bickmore,et al.  Bone marrow-derived SP cells can contribute to the respiratory tract of mice in vivo , 2005, Journal of Cell Science.

[57]  Jennifer L West,et al.  Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration. , 2005, Biomaterials.

[58]  D. Mooney,et al.  Long-term in vivo gene expression via delivery of PEI-DNA condensates from porous polymer scaffolds. , 2005, Human gene therapy.

[59]  T. Segura,et al.  DNA delivery from hyaluronic acid-collagen hydrogels via a substrate-mediated approach. , 2005, Biomaterials.

[60]  S. Ramakrishna,et al.  Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibers and their potential in neural tissue engineering. , 2005, Biomaterials.

[61]  M. Akashi,et al.  Tough, Thin Hydrogel Membranes with Giant Crystalline Domains Composed of Precisely Synthesized Macromolecules , 2005 .

[62]  Daniel G. Anderson,et al.  Structure/property studies of polymeric gene delivery using a library of poly(β-amino esters). , 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

[63]  D. Mooney,et al.  Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4) , 2005, Gene Therapy.

[64]  M. Pittenger,et al.  Human mesenchymal stem cells modulate allogeneic immune cell responses. , 2005, Blood.

[65]  Antonios G Mikos,et al.  Dual growth factor delivery from degradable oligo(poly(ethylene glycol) fumarate) hydrogel scaffolds for cartilage tissue engineering. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[66]  Yangzhi Guping,et al.  A New Biodegradable Poly-Amino Acid: α,β-Poly[(N-Hydroxypropyl/Aminoethyl)-DL-Aspartamide-co-L-Lysine], A Potential Nonviral Vector for Gene Delivery , 2005 .

[67]  J. Elisseeff,et al.  Musculoskeletal Differentiation of Cells Derived from Human Embryonic Germ Cells , 2005, Stem cells.

[68]  D W Hutmacher,et al.  Fabrication using a rapid prototyping system and in vitro characterization of PEG-PCL-PLA scaffolds for tissue engineering , 2005, Journal of biomaterials science. Polymer edition.

[69]  J. Hubbell,et al.  Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering , 2005, Nature Biotechnology.

[70]  Thomas Boland,et al.  Rapid prototyping of tissue-engineering constructs, using photopolymerizable hydrogels and stereolithography. , 2004, Tissue engineering.

[71]  Robert Langer,et al.  A polymer library approach to suicide gene therapy for cancer. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[72]  C K Chua,et al.  Development of tissue scaffolds using selective laser sintering of polyvinyl alcohol/hydroxyapatite biocomposite for craniofacial and joint defects , 2004, Journal of materials science. Materials in medicine.

[73]  J. Karp,et al.  Fibrin-filled scaffolds for bone-tissue engineering: An in vivo study. , 2004, Journal of biomedical materials research. Part A.

[74]  R. Oreffo,et al.  Gene delivery in bone tissue engineering: progress and prospects using viral and nonviral strategies. , 2004, Tissue engineering.

[75]  Christine E Schmidt,et al.  Development of photocrosslinkable hyaluronic acid-polyethylene glycol-peptide composite hydrogels for soft tissue engineering. , 2004, Journal of biomedical materials research. Part A.

[76]  M. Filbin,et al.  cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury , 2004, Nature Medicine.

[77]  Christopher H Contag,et al.  Adipose-derived adult stromal cells heal critical-size mouse calvarial defects , 2004, Nature Biotechnology.

[78]  E. Wagner,et al.  Targeted nucleic acid delivery into tumors: new avenues for cancer therapy. , 2004, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[79]  R. Langer,et al.  Designing materials for biology and medicine , 2004, Nature.

[80]  Sung Keun Kang,et al.  Evidence of a Pluripotent Human Embryonic Stem Cell Line Derived from a Cloned Blastocyst , 2004, Science.

[81]  Tejal A Desai,et al.  Layer-by-layer microfluidics for biomimetic three-dimensional structures. , 2004, Biomaterials.

[82]  S. Haynesworth,et al.  Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation , 2004, Bone Marrow Transplantation.

[83]  D. Wendt,et al.  The role of bioreactors in tissue engineering. , 2004, Trends in biotechnology.

[84]  Glenn D Prestwich,et al.  Attachment and spreading of fibroblasts on an RGD peptide-modified injectable hyaluronan hydrogel. , 2004, Journal of biomedical materials research. Part A.

[85]  Wenlei Jiang,et al.  Stabilization and Controlled Release of Bovine Serum Albumin Encapsulated in Poly(D, L-lactide) and Poly(ethylene glycol) Microsphere Blends , 2001, Pharmaceutical Research.

[86]  J. Cleland,et al.  A Large-Scale Process to Produce Microencapsulated Proteins , 1998, Pharmaceutical Research.

[87]  E. D. Rekow,et al.  Performance of hydroxyapatite bone repair scaffolds created via three-dimensional fabrication techniques. , 2003, Journal of biomedical materials research. Part A.

[88]  David J Mooney,et al.  Fabrication and in vitro testing of polymeric delivery system for condensed DNA. , 2003, Journal of biomedical materials research. Part A.

[89]  D. Wendt,et al.  Oscillating perfusion of cell suspensions through three‐dimensional scaffolds enhances cell seeding efficiency and uniformity , 2003, Biotechnology and bioengineering.

[90]  David J Mooney,et al.  Protein-based signaling systems in tissue engineering. , 2003, Current opinion in biotechnology.

[91]  M. Rots,et al.  Protein transduction domains and their utility in gene therapy. , 2003, Current gene therapy.

[92]  Akin Akinc,et al.  Synthesis of poly (β-amino ester)s optimized for highly effective gene delivery , 2003 .

[93]  J. Davies,et al.  Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion. , 2003, Experimental hematology.

[94]  Daniel G. Anderson,et al.  Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery. , 2003, Angewandte Chemie.

[95]  Christine E Schmidt,et al.  Photocrosslinked hyaluronic acid hydrogels: natural, biodegradable tissue engineering scaffolds. , 2003, Biotechnology and bioengineering.

[96]  K. Leong,et al.  Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs. , 2003, Biomaterials.

[97]  T. Boland,et al.  Cell and organ printing 2: fusion of cell aggregates in three-dimensional gels. , 2003, The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology.

[98]  Robert Langer,et al.  Parallel synthesis and biophysical characterization of a degradable polymer library for gene delivery. , 2003, Journal of the American Chemical Society.

[99]  S. Waldman,et al.  Effect of Biomechanical Conditioning on Cartilaginous Tissue Formation in Vitro , 2003, The Journal of bone and joint surgery. American volume.

[100]  A J Verbout,et al.  Viable osteogenic cells are obligatory for tissue-engineered ectopic bone formation in goats. , 2003, Tissue engineering.

[101]  B Derby,et al.  Novel collagen scaffolds with predefined internal morphology made by solid freeform fabrication. , 2003, Biomaterials.

[102]  Malcolm N. Cooke,et al.  Use of stereolithography to manufacture critical-sized 3D biodegradable scaffolds for bone ingrowth. , 2003, Journal of biomedical materials research. Part B, Applied biomaterials.

[103]  Larry V McIntire.  WTEC panel report on tissue engineering. , 2003, Tissue engineering.

[104]  O. Ringdén,et al.  Mesenchymal Stem Cells Inhibit and Stimulate Mixed Lymphocyte Cultures and Mitogenic Responses Independently of the Major Histocompatibility Complex , 2003, Scandinavian journal of immunology.

[105]  Ernst Wagner,et al.  Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer. , 2003, Bioconjugate chemistry.

[106]  Yasuhiko Tabata,et al.  Tissue regeneration based on growth factor release. , 2003, Tissue engineering.

[107]  Virginie Sottile,et al.  In vitro osteogenic differentiation of human ES cells. , 2003, Cloning and stem cells.

[108]  A J Verbout,et al.  Evaluating 3D bone tissue engineered constructs with different seeding densities using the alamarBlue™ assay and the effect on in vivo bone formation , 2002, Journal of materials science. Materials in medicine.

[109]  S. Bhatia,et al.  Three-Dimensional Photopatterning of Hydrogels Containing Living Cells , 2002 .

[110]  B. Schumacher,et al.  Images in cardiovascular medicine. Fistulous communication between coronary sinus and left atrium. , 2002, Circulation.

[111]  Jindrich Kopecek,et al.  Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. , 2002, Advanced drug delivery reviews.

[112]  F. Szoka,et al.  Robust and prolonged gene expression from injectable polymeric implants , 2002, Gene Therapy.

[113]  Y. Lim,et al.  Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and nontoxic gene delivery carrier. , 2002, Bioconjugate chemistry.

[114]  J. Sanders,et al.  Prevascularization of a biomaterial using a chorioallontoic membrane. , 2002, Microvascular research.

[115]  Samuel I Stupp,et al.  Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[116]  D. Jans,et al.  Using nuclear targeting signals to enhance non‐viral gene transfer , 2002, Immunology and cell biology.

[117]  W. Mark Saltzman,et al.  Building drug delivery into tissue engineering design , 2002, Nature Reviews Drug Discovery.

[118]  L. Griffith,et al.  Tissue Engineering--Current Challenges and Expanding Opportunities , 2002, Science.

[119]  R. Cartier,et al.  Utilization of synthetic peptides containing nuclear localization signals for nonviral gene transfer systems , 2002, Gene Therapy.

[120]  David G Simpson,et al.  Electrospinning of collagen nanofibers. , 2002, Biomacromolecules.

[121]  V Vécsei,et al.  Dedifferentiation-associated changes in morphology and gene expression in primary human articular chondrocytes in cell culture. , 2002, Osteoarthritis and cartilage.

[122]  Steven P Schwendeman,et al.  Recent advances in the stabilization of proteins encapsulated in injectable PLGA delivery systems. , 2002, Critical reviews in therapeutic drug carrier systems.

[123]  K. Leong,et al.  The design of scaffolds for use in tissue engineering. Part I. Traditional factors. , 2001, Tissue engineering.

[124]  M. Wiberg,et al.  A novel use of alginate hydrogel as Schwann cell matrix. , 2001, Tissue engineering.

[125]  M J Lysaght,et al.  The growth of tissue engineering. , 2001, Tissue engineering.

[126]  H. Merkle,et al.  Hydrophilic poly(DL-lactide-co-glycolide) microspheres for the delivery of DNA to human-derived macrophages and dendritic cells. , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[127]  A. Fire,et al.  Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[128]  R. Langer,et al.  Accelerated discovery of synthetic transfection vectors: parallel synthesis and screening of a degradable polymer library. , 2001, Journal of the American Chemical Society.

[129]  S. Bruder,et al.  Mesenchymal stem cells: building blocks for molecular medicine in the 21st century. , 2001, Trends in molecular medicine.

[130]  T. Tuschl,et al.  Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.

[131]  R. Green,et al.  The Ethical Reasons for Stem Cell Research , 2001, Science.

[132]  I Zein,et al.  Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling. , 2001, Journal of biomedical materials research.

[133]  L. Barrett,et al.  Sustained Effects of Gene-Activated Matrices after CNS Injury , 2001, Molecular and Cellular Neuroscience.

[134]  H. Lorenz,et al.  Multilineage cells from human adipose tissue: implications for cell-based therapies. , 2001, Tissue engineering.

[135]  K. Hasegawa,et al.  Cross-linked hyaluronate hydrogel prevents adhesion formation and reformation in mouse uterine horn model. , 2001, Human reproduction.

[136]  J. Nickerson,et al.  Experimental observations of a nuclear matrix. , 2001, Journal of cell science.

[137]  H. Aro,et al.  Pore diameter of more than 100 μm is not requisite for bone ingrowth in rabbits , 2001 .

[138]  David J. Mooney,et al.  Controlled growth factor release from synthetic extracellular matrices , 2000, Nature.

[139]  R. Levy,et al.  Sustained delivery and expression of DNA encapsulated in polymeric nanoparticles , 2000, Gene Therapy.

[140]  Robert Langer,et al.  Degradable Poly(β-amino esters): Synthesis, Characterization, and Self-Assembly with Plasmid DNA , 2000 .

[141]  Rolf Mülhaupt,et al.  Desktop manufacturing of complex objects, prototypes and biomedical scaffolds by means of computer‐assisted design combined with computer‐guided 3D plotting of polymers and reactive oligomers , 2000 .

[142]  G F Pierce,et al.  Collagen-embedded platelet-derived growth factor DNA plasmid promotes wound healing in a dermal ulcer model. , 2000, The Journal of surgical research.

[143]  H. Redmond,et al.  Is human fracture hematoma inherently angiogenic , 2000 .

[144]  A. Meunier,et al.  Tissue-engineered bone regeneration , 2000, Nature Biotechnology.

[145]  R. Biran,et al.  Cellular transplants as sources for therapeutic agents. , 2000, Advanced drug delivery reviews.

[146]  B L Currier,et al.  Biological activity of rhBMP-2 released from PLGA microspheres. , 2000, Journal of biomechanical engineering.

[147]  M. Brittberg,et al.  Two- to 9-Year Outcome After Autologous Chondrocyte Transplantation of the Knee , 2000, Clinical orthopaedics and related research.

[148]  D. Odde,et al.  Laser-guided direct writing of living cells. , 2000, Biotechnology and bioengineering.

[149]  Stephen E. Feinberg,et al.  An image-based approach for designing and manufacturing craniofacial scaffolds. , 2000, International journal of oral and maxillofacial surgery.

[150]  A. Simpson,et al.  TISSUES FORMED DURING DISTRACTION OSTEOGENESIS IN THE RABBIT ARE DETERMINED BY THE DISTRACTION RATE: LOCALIZATION OF THE CELLS THAT EXPRESS THE mRNAs AND THE DISTRIBUTION OF TYPES I AND II COLLAGENS , 2000, Cell biology international.

[151]  S. Schwendeman,et al.  Stabilization of proteins encapsulated in injectable poly (lactide-co-glycolide) , 2000, Nature Biotechnology.

[152]  A. Klibanov,et al.  Protein stability in controlled-release systems , 2000, Nature Biotechnology.

[153]  M. West,et al.  Prospects for the use of nuclear transfer in human transplantation , 1999, Nature Biotechnology.

[154]  F J Schoen,et al.  Cardiac tissue engineering: cell seeding, cultivation parameters, and tissue construct characterization. , 1999, Biotechnology and bioengineering.

[155]  R J Cohen,et al.  Cardiac muscle tissue engineering: toward an in vitro model for electrophysiological studies. , 1999, American journal of physiology. Heart and circulatory physiology.

[156]  K E Healy,et al.  Designing Biomaterials to Direct Biological Responses , 1999, Annals of the New York Academy of Sciences.

[157]  David J. Mooney,et al.  DNA delivery from polymer matrices for tissue engineering , 1999, Nature Biotechnology.

[158]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[159]  L. Barrett,et al.  Factors affecting blood clearance and in vivo distribution of polyelectrolyte complexes for gene delivery , 1999, Gene Therapy.

[160]  T. Stockley,et al.  The in vivo delivery of heterologous proteins by microencapsulated recombinant cells. , 1999, Trends in biotechnology.

[161]  B. Obradovic,et al.  Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue‐engineered cartilage , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[162]  D J Mooney,et al.  Alginate hydrogels as synthetic extracellular matrix materials. , 1999, Biomaterials.

[163]  Peter J. Donovan,et al.  Derivation of pluripotent stem cells from cultured human primordial germ cells , 1998 .

[164]  J. Thomson,et al.  Embryonic stem cell lines derived from human blastocysts. , 1998, Science.

[165]  C. Plank,et al.  Application of membrane-active peptides for drug and gene delivery across cellular membranes. , 1998, Advanced drug delivery reviews.

[166]  A. Fire,et al.  Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans , 1998, Nature.

[167]  J. Hubbell,et al.  Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing. , 1998, Journal of biomedical materials research.

[168]  J. Aubin,et al.  Bone stem cells , 1998, Journal of cellular biochemistry.

[169]  R Langer,et al.  Dynamic Cell Seeding of Polymer Scaffolds for Cartilage Tissue Engineering , 1998, Biotechnology progress.

[170]  R. Langer,et al.  Evaluation of solute permeation through the stratum corneum: lateral bilayer diffusion as the primary transport mechanism. , 1997, Journal of pharmaceutical sciences.

[171]  During,et al.  Adeno-associated virus as a gene delivery system. , 1997, Advanced drug delivery reviews.

[172]  Rakesh K. Jain,et al.  Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation , 1997, Nature Medicine.

[173]  K. Mislick,et al.  Evidence for the role of proteoglycans in cation-mediated gene transfer. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[174]  Hiromitsu Nakauchi,et al.  Long-Term Lymphohematopoietic Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem Cell , 1996, Science.

[175]  R Langer,et al.  Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents. , 1996, Biomaterials.

[176]  R. Vile,et al.  Retroviral vectors , 1996 .

[177]  W. Saltzman,et al.  Stabilization of nerve growth factor in controlled release polymers and in tissue. , 1996, Journal of biomaterials science. Polymer edition.

[178]  M. Cima,et al.  Mechanical properties of dense polylactic acid structures fabricated by three dimensional printing. , 1996, Journal of biomaterials science. Polymer edition.

[179]  D. Scherman,et al.  A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[180]  Jeffrey A. Hubbell,et al.  Biomaterials in Tissue Engineering , 1995, Bio/Technology.

[181]  K. Leong,et al.  Fabrication of controlled release biodegradable foams by phase separation. , 1995, Tissue engineering.

[182]  S. Bruder,et al.  Mesenchymal stem cells in bone development, bone repair, and skeletal regenaration therapy , 1994 .

[183]  C. Ohlsson,et al.  Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. , 1994, The New England journal of medicine.

[184]  N A Peppas,et al.  New challenges in biomaterials. , 1994, Science.

[185]  R Langer,et al.  Design and Fabrication of Biodegradable Polymer Devices to Engineer Tubular Tissues , 1994, Cell transplantation.

[186]  F. Szoka,et al.  Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. , 1993, Bioconjugate chemistry.

[187]  T. Arakawa,et al.  Dehydration-induced conformational transitions in proteins and their inhibition by stabilizers. , 1993, Biophysical journal.

[188]  R Langer,et al.  Cell seeding in porous transplantation devices. , 1993, Biomaterials.

[189]  R Langer,et al.  Controlled and modulated release of basic fibroblast growth factor. , 1991, Biomaterials.

[190]  R Langer,et al.  Selective cell transplantation using bioabsorbable artificial polymers as matrices. , 1988, Journal of pediatric surgery.

[191]  M J Bissell,et al.  How does the extracellular matrix direct gene expression? , 1982, Journal of theoretical biology.

[192]  N. Dagalakis,et al.  Design of an artificial skin. Part III. Control of pore structure. , 1980, Journal of biomedical materials research.

[193]  R. Langer,et al.  Polymers for the sustained release of proteins and other macromolecules , 1976, Nature.

[194]  J. Folkman.  Tumor angiogenesis: therapeutic implications. , 1971, The New England journal of medicine.

[195]  J Folkman,et al.  Transplacental carcinogenesis by stilbestrol. , 1971, The New England journal of medicine.

[196]  S F Hulbert,et al.  Potential of ceramic materials as permanently implantable skeletal prostheses. , 1970, Journal of biomedical materials research.