The Influence Of Plasticizers On Determination of Cationic Surfactants In Pharmaceutical Disinfectants By Direct Potentiometric Surfactant Sensor

Ion selective liquid membrane type membranes are usually made of a PVC, ionophore and a plasticizer. Plasticizers soften the PVC but due to their lipophilicity they influence the ionophore, the ion exchange across the membrane, membrane resistance and consequently the analytical signal. The aim of the research was to investigate the influence of four different plasticizers, in formulation with the same ionophore, on the analytical properties of the sensor membrane towards two often used cationic surfactants, then select the best membrane formulation and test it on real samples of six pharmaceutical disinfectants containing cationic surfactants.