Recent advances in nanoplasmonic biosensors: applications and lab-on-a-chip integration

Abstract Motivated by the recent progress in the nanofabrication field and the increasing demand for cost-effective, portable, and easy-to-use point-of-care platforms, localized surface plasmon resonance (LSPR) biosensors have been subjected to a great scientific interest in the last few years. The progress observed in the research of this nanoplasmonic technology is remarkable not only from a nanostructure fabrication point of view but also in the complete development and integration of operative devices and their application. The potential benefits that LSPR biosensors can offer, such as sensor miniaturization, multiplexing opportunities, and enhanced performances, have quickly positioned them as an interesting candidate in the design of lab-on-a-chip (LOC) optical biosensor platforms. This review covers specifically the most significant achievements that occurred in recent years towards the integration of this technology in compact devices, with views of obtaining LOC devices. We also discuss the most relevant examples of the use of the nanoplasmonic biosensors for real bioanalytical and clinical applications from assay development and validation to the identification of the implications, requirements, and challenges to be surpassed to achieve fully operative devices.

[1]  M. Lamy,et al.  Sepsis and serum cytokine concentrations. , 1997, Critical care medicine.

[2]  J. Foster,et al.  The functions of cytokines and their uses in toxicology , 2001, International journal of experimental pathology.

[3]  J. Foster.  The functions of cytokines and their uses in toxicology. , 2001, International journal of experimental pathology.

[4]  H. Fredriksson,et al.  Hole–Mask Colloidal Lithography , 2007 .

[5]  J. Homola.  Surface plasmon resonance sensors for detection of chemical and biological species. , 2008, Chemical reviews.

[6]  Julien Reboud,et al.  Palm-sized biodetection system based on localized surface plasmon resonance. , 2008, Analytical chemistry.

[7]  Mikael Käll,et al.  Refractometric sensing using propagating versus localized surface plasmons: a direct comparison. , 2009, Nano letters.

[8]  Laura M Lechuga,et al.  Identification of the optimal spectral region for plasmonic and nanoplasmonic sensing. , 2010, ACS nano.

[9]  Alp Artar,et al.  High-throughput nanofabrication of infrared plasmonic nanoantenna arrays for vibrational nanospectroscopy. , 2010, Nano letters.

[10]  Vamsy P. Chodavarapu,et al.  A Camera Phone Localised Surface Plasmon Biosensing Platform towards Low-Cost Label-Free Diagnostic Testing , 2011, J. Sensors.

[11]  K. Yong,et al.  A Review on Functionalized Gold Nanoparticles for Biosensing Applications , 2011 .

[12]  F. Theil,et al.  Surface-enhanced Raman spectroscopy (SERS): progress and trends , 2012, Analytical and Bioanalytical Chemistry.

[13]  J. Hafner,et al.  Localized surface plasmon resonance sensors. , 2011, Chemical reviews.

[14]  M. A. Otte,et al.  Guiding light in monolayers of sparse and random plasmonic meta-atoms. , 2011, ACS nano.

[15]  Marek Piliarik,et al.  High-resolution biosensor based on localized surface plasmons. , 2012, Optics express.

[16]  Ilker S. Bayer,et al.  Advances in top-down and bottom-up surface nanofabrication: techniques, applications & future prospects. , 2012, Advances in colloid and interface science.

[17]  J. Homola,et al.  Analytical value of detecting an individual molecular binding event: the case of the surface plasmon resonance biosensor. , 2012, Analytical chemistry.

[18]  Anke Suska,et al.  Embedded Adaptive Optics for Ubiquitous Lab-on-a-Chip Readout on Intact Cell Phones , 2012, Sensors.

[19]  M. A. Otte,et al.  Figures of Merit for Refractometric LSPR Biosensing , 2012 .

[20]  Fredrik Höök,et al.  Material-selective surface chemistry for nanoplasmonic sensors: optimizing sensitivity and controlling binding to local hot spots. , 2012, Nano letters.

[21]  D. Filippini,et al.  Surface plasmon resonance chemical sensing on cell phones. , 2012, Angewandte Chemie.

[22]  Richard P Van Duyne,et al.  A localized surface plasmon resonance imaging instrument for multiplexed biosensing. , 2013, Analytical chemistry.

[23]  Byung-Chan Kim,et al.  Highly sensitive localized surface plasmon resonance immunosensor for label-free detection of HIV-1. , 2013, Nanomedicine : nanotechnology, biology, and medicine.

[24]  Zhenyu Lin,et al.  Discrimination of enantiomers based on LSPR biosensors fabricated with weak enantioselective and nonselective receptors. , 2013, Biosensors & bioelectronics.

[25]  Kenji Yokoyama,et al.  Localized surface plasmon resonance detection of biological toxins using cell surface oligosaccharides on glyco chips. , 2013, ACS applied materials & interfaces.

[26]  Rudi Cloots,et al.  Nanosphere lithography: a powerful method for the controlled manufacturing of nanomaterials , 2013 .

[27]  Guohui Xiao,et al.  Plasmonic gold mushroom arrays with refractive index sensing figures of merit approaching the theoretical limit , 2013, Nature Communications.

[28]  S. Kosa,et al.  Extraction of nanosized cobalt sulfide from spent hydrocracking catalyst , 2013 .

[29]  Andreas B. Dahlin,et al.  Promises and challenges of nanoplasmonic devices for refractometric biosensing , 2013, Nanophotonics.

[30]  Gennady Shvets,et al.  Fano-resonant metamaterials and their applications , 2013 .

[31]  B. Lippitz,et al.  Cytokine patterns in patients with cancer: a systematic review. , 2013, The Lancet. Oncology.

[32]  F. Fang,et al.  Focused Ion Beam Nanofabrication Technology , 2013 .

[33]  M. Gartia,et al.  Colorimetric Plasmon Resonance Imaging Using Nano Lycurgus Cup Arrays , 2013 .

[34]  Muthukumaran Packirisamy,et al.  Integration of gold nanoparticles in PDMS microfluidics for lab-on-a-chip plasmonic biosensing of growth hormones. , 2013, Biosensors & bioelectronics.

[35]  Yongkang Gao,et al.  Breakthroughs in Photonics 2013: Research Highlights on Biosensors Based on Plasmonic Nanostructures , 2014, IEEE Photonics Journal.

[36]  Jung Ho Park,et al.  Nanopatterning by laser interference lithography: applications to optical devices. , 2014, Journal of nanoscience and nanotechnology.

[37]  M. A. Otte,et al.  Trends and challenges of refractometric nanoplasmonic biosensors: a review. , 2014, Analytica chimica acta.

[38]  Amarjyoti Choudhury,et al.  Evanescent Wave Coupled Spectroscopic Sensing Using Smartphone , 2014, IEEE Photonics Technology Letters.

[39]  P Neužil,et al.  From chip-in-a-lab to lab-on-a-chip: towards a single handheld electronic system for multiple application-specific lab-on-a-chip (ASLOC). , 2014, Lab on a chip.

[40]  Laura M. Lechuga,et al.  Direct Detection of Protein Biomarkers in Human Fluids Using Site-Specific Antibody Immobilization Strategies , 2014, Sensors.

[41]  Khairudin Mohamed,et al.  A review of roll-to-roll nanoimprint lithography , 2014, Nanoscale Research Letters.

[42]  Hakho Lee,et al.  Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor , 2014, Nature Biotechnology.

[43]  Daniel Filippini,et al.  Biosensing with cell phones. , 2014, Trends in biotechnology.

[44]  Aydogan Ozcan,et al.  Handheld high-throughput plasmonic biosensor using computational on-chip imaging , 2014, Light: Science & Applications.

[45]  S. Maerkl,et al.  LSPR chip for parallel, rapid, and sensitive detection of cancer markers in serum. , 2014, Nano letters.

[46]  Katsuo Kurabayashi,et al.  Integrated Nanoplasmonic Sensing for Cellular Functional Immunoanalysis Using Human Blood , 2014, ACS nano.

[47]  Murray Korc,et al.  Highly Specific Plasmonic Biosensors for Ultrasensitive MicroRNA Detection in Plasma from Pancreatic Cancer Patients , 2014, Nano letters.

[48]  S. Ng,et al.  Development of Localized Surface Plasmon Resonance-Based Point-of-Care System , 2014, Plasmonics.

[49]  A. E. Cetin,et al.  Lensfree optofluidic plasmonic sensor for real-time and label-free monitoring of molecular binding events over a wide field-of-view , 2014, Scientific Reports.

[50]  Ivan B. Djordjevic,et al.  Coherent Multimode OAM Superpositions for Multidimensional Modulation , 2014, IEEE Photonics Journal.

[51]  J. Byun,et al.  A regeneratable, label-free, localized surface plasmon resonance (LSPR) aptasensor for the detection of ochratoxin A. , 2014, Biosensors & bioelectronics.

[52]  Utkan Demirci,et al.  Advances in Plasmonic Technologies for Point of Care Applications , 2014, Chemical reviews.

[53]  Emily B Hanhauser,et al.  Multitarget, quantitative nanoplasmonic electrical field-enhanced resonating device (NE2RD) for diagnostics , 2015, Proceedings of the National Academy of Sciences.

[54]  Laura M Lechuga,et al.  Highly sensitive dendrimer-based nanoplasmonic biosensor for drug allergy diagnosis. , 2015, Biosensors & bioelectronics.

[55]  Hongzong Yin,et al.  Detection of Bacillus thuringiensis Cry1Ab protein based on surface plasmon resonance immunosensor. , 2015, Analytical biochemistry.

[56]  Masato Saito,et al.  Parallelized label-free detection of protein interactions using a hyper-spectral imaging system , 2015 .

[57]  Yifang Chen,et al.  Nanofabrication by electron beam lithography and its applications , 2015 .

[58]  Sang Jun Sim,et al.  Single gold nanoplasmonic sensor for clinical cancer diagnosis based on specific interaction between nucleic acids and protein. , 2015, Biosensors & bioelectronics.

[59]  Qihua Xiong,et al.  Engineering plasmonic nanorod arrays for colon cancer marker detection. , 2015, Biosensors & bioelectronics.

[60]  Pei-Kuen Wei,et al.  Ultrasensitive Biosensors Using Enhanced Fano Resonances in Capped Gold Nanoslit Arrays , 2015, Scientific Reports.

[61]  Plasmonic sensors for the competitive detection of testosterone. , 2015, The Analyst.

[62]  Mohd Hafizi Ahmad,et al.  Temperature effect on electrical treeing and partial discharge characteristics of silicone rubber-based nanocomposites , 2015 .

[63]  Sang Jun Sim,et al.  Nanoplasmonic biosensor: detection and amplification of dual bio-signatures of circulating tumor DNA. , 2015, Biosensors & bioelectronics.

[64]  Banafsheh Abasahl,et al.  Cavity-Coupled Plasmonic Device with Enhanced Sensitivity and Figure-of-Merit. , 2015, ACS nano.

[65]  M. Korc,et al.  Label-Free Nanoplasmonic-Based Short Noncoding RNA Sensing at Attomolar Concentrations Allows for Quantitative and Highly Specific Assay of MicroRNA-10b in Biological Fluids and Circulating Exosomes , 2015, ACS nano.

[66]  W. Peng,et al.  Surface Plasmon Resonance Biosensor Based on Smart Phone Platforms , 2015, Scientific Reports.

[67]  Jianping Fu,et al.  Supplementary Information for Multiplex Serum Cytokine Immunoassay Using Nanoplasmonic Biosensor Microarrays , 2015 .

[68]  Carlotta Guiducci,et al.  Label-free detection of tobramycin in serum by transmission-localized surface plasmon resonance. , 2015, Analytical chemistry.

[69]  E. Li,et al.  Focused ion beam assisted interface detection for fabricating functional plasmonic nanostructures , 2015 .

[70]  Jiří Homola,et al.  Functionalizable low-fouling coatings for label-free biosensing in complex biological media: advances and applications , 2015, Analytical and Bioanalytical Chemistry.

[71]  Ian Bruzas,et al.  Patterned Plasmonic Nanoparticle Arrays for Microfluidic and Multiplexed Biological Assays. , 2015, Analytical chemistry.

[72]  Fredrik Höök,et al.  Influence of the Evanescent Field Decay Length on the Sensitivity of Plasmonic Nanodisks and Nanoholes , 2015 .

[73]  P. Wei,et al.  Nanoplasmonic biochips for rapid label-free detection of imidacloprid pesticides with a smartphone. , 2016, Biosensors & bioelectronics.