Establishment of a production process for a novel vaccine candidate against Lawsonia intracellularis

[1]  F. Conceição,et al.  Inactivated recombinant Escherichia coli as a candidate vaccine against Clostridium perfringens alpha toxin in sheep. , 2019, Anaerobe.

[2]  Germán L. Rosano,et al.  New tools for recombinant protein production in Escherichia coli: A 5‐year update , 2019, Protein science : a publication of the Protein Society.

[3]  Y. Ahn,et al.  Enhanced Production of Recombinant Alcohol Dehydrogenase Using the Genetically Engineered Escherichia coli Strain that Heterologously Expresses Carrot Heat Shock Protein 70 , 2019, Current Microbiology.

[4]  Danilo Correddu,et al.  An improved method for the heterologous production of soluble human ribosomal proteins in Escherichia coli , 2019, Scientific Reports.

[5]  S. Taguchi,et al.  High-cell density culture of poly(lactate-co-3-hydroxybutyrate)-producing Escherichia coli by using glucose/xylose-switching fed-batch jar fermentation. , 2019, Journal of bioscience and bioengineering.

[6]  M. Hoeijmakers,et al.  Efficacy of a novel inactivated Lawsonia intracellularis vaccine in pigs against experimental infection and under field conditions. , 2019, Vaccine.

[7]  R. Montesino,et al.  Multi-antigenic recombinant subunit vaccine against Lawsonia intracellularis: The etiological agent of porcine proliferative enteropathy. , 2019, Vaccine.

[8]  Babbal,et al.  Bioprocess optimization for the overproduction of catalytic domain of ubiquitin-like protease 1 (Ulp1) from S. cerevisiae in E. coli fed-batch culture. , 2019, Enzyme and microbial technology.

[9]  M. Wu,et al.  Optimized production of insulin variant, a recombinant platelet aggregation inhibitor, by high cell-density fermentation of recombinant Escherichia coli. , 2018, Protein expression and purification.

[10]  Victória Furtado Migliavacca,et al.  Production of recombinant β-galactosidase in bioreactors by fed-batch culture using DO-stat and linear control , 2018, Biocatalysis and Biotransformation.

[11]  Keun Kim,et al.  Statistical optimization of culture medium to produce recombinant viral protein by Escherichia coli host for diagnostic kit to detect human immunodeficiency virus (HIV) infection. , 2018, Biochemical and biophysical research communications.

[12]  M. Vitolo,et al.  Microbial cell disruption methods for efficient release of enzyme L-asparaginase , 2018, Preparative biochemistry & biotechnology.

[13]  Oliver Spadiut,et al.  Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3) , 2017, Bioengineering.

[14]  Y. Chisti,et al.  Production of carotenoids and lipids by Rhodococcus opacus PD630 in batch and fed-batch culture , 2016, Bioprocess and Biosystems Engineering.

[15]  S. Finkel,et al.  Rich Medium Composition Affects Escherichia coli Survival, Glycation, and Mutation Frequency during Long-Term Batch Culture , 2015, Applied and Environmental Microbiology.

[16]  P. Heegaard,et al.  Vaccination of pigs with attenuated Lawsonia intracellularis induced acute phase protein responses and primed cell-mediated immunity without reduction in bacterial shedding after challenge. , 2015, Vaccine.

[17]  I. Barchia,et al.  The critical threshold of Lawsonia intracellularis in pig faeces that causes reduced average daily weight gains in experimentally challenged pigs. , 2014, Veterinary microbiology.

[18]  W. H. Kampen.  Chapter 4 – Nutritional Requirements in Fermentation Processes , 2014 .

[19]  D. Emery,et al.  Immunological responses to vaccination following experimental Lawsonia intracellularis virulent challenge in pigs. , 2013, Veterinary microbiology.

[20]  Špela Peternel.  Bacterial cell disruption: a crucial step in protein production. , 2013, New biotechnology.

[21]  C. S. Kristensen,et al.  Investigation of the association of growth rate in grower-finishing pigs with the quantification of Lawsonia intracellularis and porcine circovirus type 2. , 2013, Preventive veterinary medicine.

[22]  J. Lessard.  Growth media for E. coli. , 2013, Methods in enzymology.

[23]  Wei Shen,et al.  Genetically switched D-lactate production in Escherichia coli. , 2012, Metabolic engineering.

[24]  C. Emrich,et al.  SHuffle, a novel Escherichia coli protein expression strain capable of correctly folding disulfide bonded proteins in its cytoplasm , 2012, Microbial Cell Factories.

[25]  Filomena Silva,et al.  Evaluating metabolic stress and plasmid stability in plasmid DNA production by Escherichia coli. , 2012, Biotechnology advances.

[26]  Esther Vázquez,et al.  Bacterial inclusion bodies: making gold from waste. , 2012, Trends in biotechnology.

[27]  S. Wattanaphansak,et al.  An Alternative Method for Cultivation of Lawsonia intracellularis , 2012, Journal of Clinical Microbiology.

[28]  J. Queiroz,et al.  Plasmid DNA fermentation strategies: influence on plasmid stability and cell physiology , 2011, Applied Microbiology and Biotechnology.

[29]  S. Lee,et al.  Fed‐batch culture of Escherichia coli for L‐valine production based on in silico flux response analysis , 2011, Biotechnology and bioengineering.

[30]  R. Komel,et al.  Isolation of biologically active nanomaterial (inclusion bodies) from bacterial cells , 2010, Microbial cell factories.

[31]  P. Neubauer,et al.  A novel fed-batch based cultivation method provides high cell-density and improves yield of soluble recombinant proteins in shaken cultures , 2010, Microbial cell factories.

[32]  O. Tolmachov.  Designing plasmid vectors. , 2009, Methods in molecular biology.

[33]  Jianguo Zhang,et al.  Optimization of culture conditions to enhance cis-epoxysuccinate hydrolase production in Escherichia coli by response surface methodology , 2008 .

[34]  Grzegorz Węgrzyn,et al.  Effects of the presence of ColE1 plasmid DNA in Escherichia coli on the host cell metabolism , 2006, Microbial Cell Factories.

[35]  Choong-Kyung Kang,et al.  Sequential and simultaneous statistical optimization by dynamic design of experiment for peptide overexpression in recombinant Escherichia coli , 2006, Applied biochemistry and biotechnology.

[36]  D. Prazeres,et al.  Optimization of the primary recovery of human interferon alpha2b from Escherichia coli inclusion bodies. , 2006, Protein expression and purification.

[37]  B. Szewczyk,et al.  Inclusion bodies from recombinant bacteria as a novel system for delivery of vaccine antigen by the oral route. , 2004, Immunology letters.

[38]  A. Bernard,et al.  Fermentation and Growth of Escherichia coli for Optimal Protein Production , 1995, Current protocols in protein science.

[39]  W. H. Kampen.  Nutritional Requirements in Fermentation Processes , 1996 .

[40]  C. Curless,et al.  Design and evaluation of a two‐stage, cyclic, recombinant fermentation process , 1991, Biotechnology and bioengineering.